Insights in column packing processes of narrow bore and capillary-scale columns: Methodologies, driving forces, and separation performance – A tutorial review

Submicron Nonporous Silica Particles for Enhanced Separation Performance in pCEC

“…We investigated several packing methods, including the pressure filling, electric filling, and gravity filling methods (Figure 3). Pressure filling is typically conducted for the packing of stainless-steel columns and capillary columns [21]. A temporary inlet frit was made at the end of the capillary by packing same-sized silica particles into a capillary with a 1 mm length, followed by sintering with a thermal stripper (Unimicro Technologies, Pleasanton, CA, USA).…”

Precise stepwise recovery of platinum group metals from high-level liquid wastes based on SDB polymer-modified SiO2

“…2(a, f ) and Table 2) are favorable to increase the solution diffusion pathway and have low mass transfer resistance for ions within the pores. 28,29 In addition, the smaller separation column inner diameter and the synthesis of homogeneous spherical dNbpy/SiO 2 -P are crucial for column experiments to control the solution flow rate, 30 which is essential for the subsequent stepwise separation of PGMs.…”

Automated Regularized Deconvolution for Eliminating Extra-Column Effects in Fast High-Efficiency Separations

“…With the availability of bonded sub-2 μm fully porous or superficially porous particles in short columns, plate heights, H , on the order of 2× particle diameter, have been routinely observed in both chiral and achiral chromatography. , Particle technology continues to challenge the engineering aspects of designing chromatographic instruments with low extra-column volumes and advanced digital filters . Reducing the physical dimensions of chromatographic systems by minimizing injector volumes, narrowing connection tubing, and optimizing flow cell geometry comes at a cost.…”