Insight in Schizophrenia: A Review

Baier, Marjorie

doi:10.1007/s11920-010-0125-7

Cited by 50 publications

(35 citation statements)

References 30 publications

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“…This result was inconsistent with Amador [20], who reported that, nearly two thirds of the patients with schizophrenia and nearly half of the subjects with manic depression (with psychosis) were unaware of being ill. Similarly, Baier [21] supported the same findings, as they found that, about third to half of schizophrenic patients had poor insight, meaning they may not acknowledge their illness or the need for treatment. Moreover, David, Buchanan, Reed, Almeida [22] found correlation between insight and severity of illness in schizophrenics in a subsequent study.…”

Section: Discussionmentioning

confidence: 58%

Patients' insight and felt stigma among psychiatric patients

Mahmoud¹,

Berma²

2016

IOSR

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Section: Discussionmentioning

confidence: 58%

Patients' insight and felt stigma among psychiatric patients

Mahmoud¹,

Berma²

2016

IOSR

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“…However, due to lack of insight associated with schizophrenia (32), some patients may not report distress. Furthermore, distress is de facto subjective and difficult to operationalize.…”

Section: Resultsmentioning

confidence: 99%

Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group Consensus Guidelines on Diagnosis and Terminology

Howes

McCutcheon

Agid

et al. 2017

AJP

800

702

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Objective Treatment resistance complicates the management of schizophrenia. Research and clinical translation is limited by inconsistent definitions. To address this we evaluated current approaches and then developed consensus criteria and guidelines. Method A systematic review of randomized antipsychotic clinical trials in treatment resistant schizophrenia was performed. Definitions of treatment resistance were extracted. Subsequently, consensus operationalized criteria were developed by a working group of researchers and clinicians through i) a multi-phase, mixed methods approach; ii) identifying key criteria via an online survey; and iii) meetings to achieve consensus. Results 42 studies met inclusion criteria. Of these, 21 (50%) studies did not provide operationalized criteria, whilst in others, criteria varied considerably, particularly regarding symptom severity, prior treatment duration and antipsychotic dose thresholds. Important for the inability to compare results, only two (5%) studies utilized the same criteria. The consensus group identified minimum and optimal criteria, employing the following principles: 1) current symptoms of a minimum duration and severity determined by a standardized rating scale; 2) ≥moderate functional impairment; 3) prior treatment consisting of ≥2 different antipsychotic trials, each for a minimum duration and dose; 4) adherence systematically assessed and meeting minimum criteria; 5) ideally at least one prospective treatment trial; 6) criteria that clearly separated responsive from treatment resistant patients. Conclusions There is considerable variation in current approaches to defining treatment resistance in schizophrenia. We present consensus guidelines that operationalize criteria for determining and reporting treatment resistance, adequate treatment and treatment response in schizophrenia, providing a benchmark for research and clinical translation.

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“…A second approach involves cognitive measures of self-disturbances such as deficits in self-agency (Frith, Blakemore, & Wolpert, 2000), awareness of action (Haggard, Martin, Taylor-Clarke, Jeannerod, & Franck, 2003), or source monitoring (Brébion, Gorman, Amador, Malaspina, & Sharif, 2002). These basic deficits may manifest themselves as a lack of insight into illness (e.g., Baier, 2010)or a lack of coherence or in personal narratives (Lysaker, Clements, Plascak-Hallberg, Knipscheer, & Wright, 2002; Lysaker et al, 2003). Moreover, these deficits may also manifest as low self-concept clarity.…”

Section: Discussionmentioning

confidence: 99%

Decreased Self-Concept Clarity in People with Schizophrenia

Cicero

Martin

Becker

et al. 2016

Journal of Nervous &Amp; Mental Disease

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Disturbances in the perception of self are thought to be central to the development of psychosis. Self-concept clarity (SCC) is the extent to which one’s beliefs about oneself are internally consistent, stable, and clear. Participants with schizophrenia (N = 54) and healthy controls (N = 32) completed the Me Not-Me Decision Task (MNMDT), in which they decided whether 60 adjectives (30 pairs of antonyms), did or did not describe themselves. SCC is conceptualized as the number of consistent responses. Participants also completed the Self-Concept Clarity Scale (SCCS). Compared to healthy controls, participants with schizophrenia scored lower on the MNMDT and SCCS, and scores were negatively correlated with positive and negative symptoms. In a simultaneous regression, SCCS scores were uniquely associated with positive symptoms, while MNMDT scores were uniquely associated with negative symptoms. This suggests that people with schizophrenia have decreased self-concept claritythat is related to positive and negative symptoms.

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Insight in Schizophrenia: A Review

Cited by 50 publications

References 30 publications

Patients' insight and felt stigma among psychiatric patients

Patients' insight and felt stigma among psychiatric patients

Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group Consensus Guidelines on Diagnosis and Terminology

Decreased Self-Concept Clarity in People with Schizophrenia

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