Insecticide resistance in vector Chagas disease: Evolution, mechanisms and management

Mougabure‐Cueto, Gastón; Picollo, María Inés

doi:10.1016/j.actatropica.2015.05.014

Cited by 125 publications

(117 citation statements)

References 91 publications

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“…In the past two decades, several studies have been published describing the different degrees of resistance of triatomine populations to insecticides (88) . However, the actual factors behind the emergence of these phenotypes are unknown and the impact of this on the development of standardized strategies for vector control are unclear (89) (90) .…”

Section: Vector Transmissionmentioning

confidence: 99%

2 nd Brazilian Consensus on Chagas Disease, 2015

Dias

Ramos

Gontijo

et al. 2016

Rev. Soc. Bras. Med. Trop.

280

449

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Section: Vector Transmissionmentioning

confidence: 99%

2 nd Brazilian Consensus on Chagas Disease, 2015

Dias

Ramos

Gontijo

et al. 2016

Rev. Soc. Bras. Med. Trop.

280

449

View full text Add to dashboard Cite

“…Population genetics analyses suggest that both phenomena are at work [41 ]. Even in extreme cases, such as independent evolution of pyrethroid resistance in the Chagas' disease vector, Triatoma infestans, at a micro-scale -for example, between neighboring dwellings -local spread from a focal point also seems to occur [42].…”

Section: Spread Of Resistance During Species Invasion or Range Expansionmentioning

confidence: 99%

Role of dispersal in resistance evolution and spread

Miller

Sappington

2017

Current Opinion in Insect Science

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Gene flow via immigration affects rate of evolution of resistance to a pest management tactic, while emigration from a resistant population can spread resistance alleles spatially. Whether resistance detected across the landscape reflects ongoing de novo evolution in different hotspots or spread from a single focal population can determine the most effective mitigation strategy. Pest dispersal dynamics determine the spatio-temporal scale at which mitigation tactics must be applied to contain or reverse resistance in an area. Independent evolution of resistance in different populations appears common but not universal. Conversely, spatial spread appears to be almost inevitable. However, rate and scale of spread depends largely on dispersal dynamics and interplay with factors such as fitness costs, spatially variable selection pressure and whether resistance alleles are spreading through an established population or being carried by populations colonizing new territory. Disciplines Ecology and Evolutionary Biology | Entomology | Genetics CommentsThis article is published as Miller, Nicholas J. and Thomas W. Sappington. "Role of dispersal in resistance evolution and spread." Current opinion in insect science 21 (2017): 68-74.

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“…2 The traditional chemical control of insect vectors faces insecticide resistance and high adaptability of the vectors to different climatic and environmental conditions. 3,4 The recent worldwide dispersion of Zika 5 and Chikungunya 6 highlight the inefficiency of current control strategies. New molecular control strategies aimed at blocking pathogen transmission have been proposed, but a better understanding of pathogen-vector interactions is required.…”

Section: No 1 Enero-febrero De 2018mentioning

confidence: 99%

Pathogen-insect interaction candidate molecules for transmission-blocking control strategies of vector borne diseases

Zumaya-Estrada¹,

Rodríguez²,

Rodrı́guez³

2017

Salud Publica Mex

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Zumaya ResumenObjetivo. Analizar el conocimiento actual de las interacciones patógeno-insecto susceptibles a incluirse en el diseño de estrategias moleculares para el control de enfermedades transmitidas por vectores. Material y métodos. Se examinaron los agentes causales de la malaria, el dengue y la enfermedad de Chagas, y las moléculas de insectos que participan en interacciones durante la infección de sus vectores. Resultados. Se presentan moléculas de patógenos que participan en la invasión del intestino del insecto y moléculas inmunes inducidas en los vectores. Se discute su inclusión en vacunas bloqueadoras de transmisión (VBT) y en la modificación genética de vectores (MGI) o de sus bacterias simbióticas. Conclusión. La interrupción de procesos mediante el bloqueo de las interacciones patógeno-vector proporciona varios candidatos para las estrategias de control molecular, pero la eficacia de VBT y MGI es aún limitada y los efectos secundarios de MGI (aumento de la transmisión de otros patógenos y afectación de otros organismos) deben descartase.

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Insecticide resistance in vector Chagas disease: Evolution, mechanisms and management

Cited by 125 publications

References 91 publications

2 nd Brazilian Consensus on Chagas Disease, 2015

2 nd Brazilian Consensus on Chagas Disease, 2015

Role of dispersal in resistance evolution and spread

Pathogen-insect interaction candidate molecules for transmission-blocking control strategies of vector borne diseases

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