Insecticidal and antifungal activities of Rheum palmatum L. anthraquinones and structurally related compounds

Shang, Xiaofei; Zhao, Zhuanjun; Li, Juncai; Yang, Guan‐Zhou; Liu, Ying‐Qian; Dai, Liyun; Zhang, Zhijun; Yang, Zhigang; Miao, Xiangshui; Yang, Cheng‐Jie; Zhang, Jiyu

doi:10.1016/j.indcrop.2019.05.055

Cited by 70 publications

(53 citation statements)

References 32 publications

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“…Methods applied for extracting quinones include maceration [116], reflux [117], Soxhlet [118,119], microwave assisted [118,120,121], ultrasonic assisted [118,122], ultrasonic-microwave assisted [123], enzyme assisted [37,124], supercritical fluid [125], sublimation assisted [38], and pressurised liquid [121,126] extractions. The applicability, requirements and results vary considerably among these methods.…”

Section: Extraction Methodsmentioning

confidence: 99%

Natural Quinone Dyes: A Review on Structure, Extraction Techniques, Analysis and Application Potential

Dulo

Phan

Githaiga

et al. 2021

Waste Biomass Valor

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Synthetic dyes are by far the most widely applied colourants in industry. However, environmental and sustainability considerations have led to an increasing efforts to substitute them with safer and more sustainable equivalents. One promising class of alternatives is the natural quinones; these are class of cyclic organic compounds characterized by a saturated (C6) ring that contains two oxygen atoms that are bonded to carbonyls and have sufficient conjugation to show color. Therefore, this study looks at the potential of isolating and applying quinone dye molecules from a sustainable source as a possible replacement for synthetic dyes. It presents an in-depth description of the three main classes of quinoid compounds in terms of their structure, occurrence biogenesis and toxicology. Extraction and purification strategies, as well as analytical methods, are then discussed. Finally, current dyeing applications are summarised. The literature review shows that natural quinone dye compounds are ubiquitous, albeit in moderate quantities, but all have a possibility of enhanced production. They also display better dyeability, stability, brightness and fastness compared to other alternative natural dyes, such as anthocyanins and carotenoids. Furthermore, they are safer for the environment than are many synthetic counterparts. Their extraction, purification and analysis are simple and fast, making them potential substitutes for their synthetic equivalents. Graphic Abstract

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Section: Extraction Methodsmentioning

confidence: 99%

Natural Quinone Dyes: A Review on Structure, Extraction Techniques, Analysis and Application Potential

Dulo

Phan

Githaiga

et al. 2021

Waste Biomass Valor

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“…The plant pathogenic fungi Botrytis cinerea, Magnaporthe oryzae , Penicillium cyclopium, Rhizopus stolonifer , Rhizoctonia solani and Sclerotinia sclerotiorum were obtained from the Agricultural Culture Collection of China. According to a previously described method ( Shang et al, 2019 ), the anti-fungal activities of the two extracts at 5 mg/ml and 2 mg/ml were determined. Briefly, Petri plates (90 mm), containing potato dextrose agar (PDA, Solarbio, China) were inoculated with 5 mm plugs of mycelia.…”

Section: Methodsmentioning

confidence: 99%

Multiple Biological Activities of Rhododendron przewalskii Maxim. Extracts and UPLC-ESI-Q-TOF/MS Characterization of Their Phytochemical Composition

Dai

Miao

et al. 2021

Front. Pharmacol.

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Backgroud:Rhododendron przewalskii Maxim. is an evergreen shrub that is used as a traditional medicine in China. However, the modern pharmacology and the chemical components of this plant has not been studied. In this paper, we aimed to investigate the antifungal, anti-inflammatory and antioxidant activities and underlying mechanism of its aqueous and ethanol extracts, and analyze their chemical composition and active compounds of R. przewalskii.Methods: The antifungal activity was determined in vitro, and anti-inflammatory and antioxidant activities and underlying mechanism of its aqueous and ethanol extracts were evaluated in vitro and in RAW 264.7 cells. The chemical composition were analyzed using UPLC-ESI-Q-TOF/MS, and the contents of six compounds were determined via HPLC.Results: Both extracts of R. przewalskii showed promising anti-inflammatory activity in vitro; decreased the production of four inflammatory cytokines, namely, nitric oxide, IL-1β, IL-6 and TNF-ɑ, in RAW 264.7 cells induced by lipopolysaccharide; and exhibited weak cytotoxicity. The extracts significantly scavenged DPPH radicals, superoxide radicals and hydroxyl radicals to exert antioxidant effects in vitro. The two extracts also exhibited cellular antioxidant activity by increasing superoxide dismutase and CAT activities and decreasing malondialdehyde content in RAW 264.7 cells induced by LPS. However, the antifungal activity of the two extracts was weak. Nine flavonoids were identified by UPLC-ESI-Q-TOF/MS. Of these, six compounds were analyzed quantitatively, including avicularin, quercetin, azaleatin, astragalin and kaempferol, and five compounds (myricetin 3-O-galactoside, paeoniflorin, astragalin, azaleatin and kaempferol) were found in this species for the first time. These compounds demonstrated antioxidant activities that were similar to those of the R. przewalskii extracts and were thought to be the active compounds in the extracts.Conclusion:R. przewalskii extracts presented promising anti-inflammatory and antioxidant activities. The extracts contained amounts of valuable flavonoids (8.98 mg/g fresh material) that were likely the active compounds in the extract contributing to the potential antioxidant activity. These results highlight the potential of R. przewalskii as a source of natural antioxidant and anti-inflammatory agents for the pharmaceutical industry.

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“…In fact, many fungal phytotoxins have other biological activities in addition to their phytotoxic activity. For example, emodin ( 86 ) exhibits antioxidant [ 342 ], antitumor [ 343 ], phytotoxic [ 86 ], insecticidal [ 344 ], antimicrobial [ 344 ], and acetylcholinesterase (AChE) and glutathione S -transferase (GST) inhibitory [ 344 ] activities. In addition, many other isolated fungal metabolites have not been evaluated for their phytotoxic activities due to either the lack of phytotoxic assays or not enough of the compounds could be isolated to perform toxicity assays.…”

Section: Conclusion and Future Perspectivesmentioning

confidence: 99%

Phytotoxic Secondary Metabolites from Fungi

Xue

Shen

et al. 2021

Toxins

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Fungal phytotoxic secondary metabolites are poisonous substances to plants produced by fungi through naturally occurring biochemical reactions. These metabolites exhibit a high level of diversity in their properties, such as structures, phytotoxic activities, and modes of toxicity. They are mainly isolated from phytopathogenic fungal species in the genera of Alternaria, Botrytis, Colletotrichum, Fusarium, Helminthosporium, and Phoma. Phytotoxins are either host specific or non-host specific phytotoxins. Up to now, at least 545 fungal phytotoxic secondary metabolites, including 207 polyketides, 46 phenols and phenolic acids, 135 terpenoids, 146 nitrogen-containing metabolites, and 11 others, have been reported. Among them, aromatic polyketides and sesquiterpenoids are the main phytotoxic compounds. This review summarizes their chemical structures, sources, and phytotoxic activities. We also discuss their phytotoxic mechanisms and structure–activity relationships to lay the foundation for the future development and application of these promising metabolites as herbicides.

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Insecticidal and antifungal activities of Rheum palmatum L. anthraquinones and structurally related compounds

Cited by 70 publications

References 32 publications

Natural Quinone Dyes: A Review on Structure, Extraction Techniques, Analysis and Application Potential

Natural Quinone Dyes: A Review on Structure, Extraction Techniques, Analysis and Application Potential

Multiple Biological Activities of Rhododendron przewalskii Maxim. Extracts and UPLC-ESI-Q-TOF/MS Characterization of Their Phytochemical Composition

Phytotoxic Secondary Metabolites from Fungi

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