Insect bites as a trigger factor of eosinophilic cellulitis

Abstract

Introduction. The study presents the case report of a Wells Syndrome in a 18-year-ld female. Wells Syndrome is a rare inflammatory skin disorder which seems to present an abnormal eosinophilic response to a number of triggers. Objective. The aim of the study is to discuss several problems related to the diagnosis and treatment of Wells Syndrome. Materials and method. Medical examination, blood tests, abdominal ultrasound and skin biopsy were performed. Results. Medical examination revealed plaques with tense blisters on feet and erythematous lesions on trunk. Blood tests showed raised anti-streptolysin O level. Skin biopsy revealed features of eosinophilic cellulitis. Oral administration of 0.5 mg per day prednisolone and antihistaminics with local therapy resulted in good clinical response. Conclusions. Sometimes several biopsy are required to establish diagnosis. In some cases lower doses of corticosteroids with antihistaminics and local anti-inflammatory treatment can by sufficient in treatment.

Cellulite non infectieuse à connaître: le syndrome de Wells

“…De nombreux facteurs déclenchants ont été décrits : piqûres d'insectes,6 cryothérapie, prise médicamenteuse (antibiotiques (pénicillines), aspirine, anti-inflammatoires non stéroïdiens, diurétiques thiazidiques, antihypertenseurs, hormones thyroïdiennes, agents biologiques (adalimumab, infliximab et ustékinumab), vaccins contenant du thiomersal, 7 etc. ), infections bactérienne (Mycoplasma pneumoniae… 8 ), fongique (Trichophyton rubrum…9 ), virale (Coxsackievirus A6, 10 herpès et varicella zoster, oreillons, parvovirus B19 chez les enfants, etc.)…”