Insect appendages and comparative ontogenetics

Angelini, David R.; Kaufman, Thomas C.

doi:10.1016/j.ydbio.2005.07.006

Cited by 172 publications

(170 citation statements)

References 114 publications

Supporting

Mentioning

161

Contrasting

Order By: Relevance

“…Most of the recent expression and functional analyses on Dll's role in mandible development collectively suggest that Dll does not play a significant role in the mandibular development of insects (Panganiban et al 1994, Popadic et al 1998, Beermann et al 2001, Angelini & Kaufman 2004, Angelini & Kaufman 2005, Simonnet & Moczek 2011, Coulcher & Telford 2013, and our a priori assumption was that Dll would not be not expressed in stag beetle mandibles. However, it is known that Dll has been independently co-opted during the development of novel traits, especially epidermal outgrowths in insects (Panganiban et al 1994, Moczek & Nagy 2005, Moczek & Rose 2009, Toga et al 2012, raising the possibility that distal patterning, including Dll expression, might have been restored in the evolution of extreme mandible size in these beetles.…”

Section: Distal-less (Dll)mentioning

confidence: 86%

Section: Organization Of the Insect Appendagementioning

confidence: 99%

“…Analysis of imaginal disc patterning in Drosophila has led to the identification of three main regions of the limb disc, with corresponding suites of genes that regulate each region: proximal (closest to the body wall), medial (the middle of the appendage), and distal (the farthest from the body wall; Kojima 2004, Angelini & Kaufman 2005. The developmental patterning of this proximal-distal axis in insect appendages is highly conserved and regulated by many genes (Kojima 2004, Angelini & Kaufman 2005. Based on previous studies of appendage morphogenesis in Drosophila and Tribolium (Lecuit & Cohen 1997, Kojima 2004, Angelini et al 2009, Angelini et al 2012, we focused on seven of these appendage-patterning genes, Distal-less (Dll), aristaless (al), Epidermal growth factor receptor (Egfr), Keren (Krn), dachshund (dac), homothorax (hth) and escargot (esg), as likely candidates for the regulation of mandible growth.…”

Section: Organization Of the Insect Appendagementioning

confidence: 99%

See 2 more Smart Citations

The function of appendage patterning genes in mandible development of the sexually dimorphic stag beetle

Gotoh

Zinna

Ishikawa

et al. 2017

Developmental Biology

View full text Add to dashboard Cite

One of the defining features of the evolutionary success of insects is the morphological diversification of their appendages, especially mouthparts. Although most insects share a common mouthpart ground plan, there is remarkable diversity in the relative size and shapes of these appendages among different insect lineages. One of the most prominent examples of mouthpart modification can be found in the enlargement of mandibles in stag beetles (Coleoptera, Insecta). In order to understand the proximate mechanisms of mouthpart modification, we investigated the function of appendage-patterning genes in mandibular enlargement during extreme growth of the sexually dimorphic mandibles of the stag beetle Cyclommatus metallifer. Based on knowledge from Drosophila and Tribolium studies, we focused on seven appendage patterning genes (Distal-less (Dll), aristaless (al), dachshund (dac), homothorax (hth), Epidermal growth factor receptor (Egfr), escargot (esg), and Keren (Krn). In order to characterize the developmental function of these genes, we performed functional analyses by using RNA interference (RNAi).Importantly, we found that RNAi knockdown of dac resulted in a significant mandible size reduction in males but not in female mandibles. In addition to reducing the size of mandibles, dac knockdown also resulted in a loss of the serrate teeth structures on the mandibles of males and females. We found that al and hth play a significant role during morphogenesis of the large male-specific inner mandibular tooth.On the other hand, knockdown of the distal selector gene Dll did not affect mandible development, supporting the hypothesis that mandibles likely do not contain the distal-most region of the ancestral appendage and therefore co-option of Dll expression is unlikely to be involved in mandible enlargement in stag beetles. In addition to mandible development, we explored possible roles of these genes in controlling the divergent antennal morphology of Coleoptera.

show abstract

Section: Distal-less (Dll)mentioning

confidence: 86%

Section: Organization Of the Insect Appendagementioning

confidence: 99%

Section: Organization Of the Insect Appendagementioning

confidence: 99%

See 1 more Smart Citation

The function of appendage patterning genes in mandible development of the sexually dimorphic stag beetle

Gotoh

Zinna

Ishikawa

et al. 2017

Developmental Biology

View full text Add to dashboard Cite

show abstract

“…It has been suggested that patterns of Hox gene expression are correlated with the evolution of novel mouthpart morphologies [37][38][39]. In Protura, Collembola and Diplura, Hox gene expression in developing mouthparts has not been studied yet; therefore, the influence of these regulatory mechanisms on the general principle is unclear.…”

Section: (C) the Evolution Of Structural Mouthpart Interactions In Inmentioning

confidence: 99%

Structural mouthpart interaction evolved already in the earliest lineages of insects

et al. 2015

View full text Add to dashboard Cite

In butterflies, bees, flies and true bugs specific mouthparts are in close contact or even fused to enable piercing, sucking or sponging of particular food sources. The common phenomenon behind these mouthpart types is a complex composed of several consecutive mouthparts which structurally interact during food uptake. The single mouthparts are thus only functional in conjunction with other adjacent mouthparts, which is fundamentally different to biting-chewing. It is, however, unclear when structural mouthpart interaction (SMI) evolved since this principle obviously occurred multiple times independently in several extant and extinct winged insect groups. Here, we report a new type of SMI in two of the earliest wingless hexapod lineagesDiplura and Collembola. We found that the mandible and maxilla interact with each other via an articulatory stud at the dorsal side of the maxillary stipes, and they are furthermore supported by structures of the hypopharynx and head capsule. These interactions are crucial stabilizing elements during food uptake. The presence of SMI in these ancestrally wingless insects, and its absence in those crustacean groups probably ancestral to insects, indicates that SMI is a groundplan apomorphy of insects. Our results thus contradict the currently established view of insect mouthpart evolution that biting-chewing mouthparts without any form of SMI are the ancestral configuration. Furthermore, SMIs occur in the earliest insects in a high anatomical variety. SMIs in stemgroup representatives of insects may have triggered efficient exploitation and fast adaptation to new terrestrial food sources much earlier than previously supposed.

show abstract

“…As such, developmental and genetic data from T. castaneum are often used in macroevolutionary comparisons to other common model insect species, especially Drosophila melanogaster (e.g. Jockusch et al, 2004;Angelini and Kaufman, 2005). For example, the larvae of T. castaneum and other coleopterans possess robust ventral appendages, and adult appendages develop from epidermal precursor cells in the larval limbs.…”

Section: Tribolium As An Experimental Organismmentioning

confidence: 99%

Relationships among pest flour beetles of the genus Tribolium (Tenebrionidae) inferred from multiple molecular markers

Angelini

Jockusch

2008

Molecular Phylogenetics and Evolution

Self Cite

View full text Add to dashboard Cite

Model species often provide initial hypotheses and tools for studies of development, genetics, and molecular evolution in closely related species. Flour beetles of the genus Tribolium MacLeay (1825) are one group with potential for such comparative studies. Tribolium castaneum (Herbst 1797) is an increasingly useful developmental genetic system. The convenience with which congeneric and other species of tenebrionid flour beetles can be reared in the laboratory makes this group attractive for comparative studies on a small phylogenetic scale. Here we present the results of phylogenetic analyses of relationships among the major pest species of Tribolium based on two mitochondrial and three nuclear markers (cytochrome oxidase 1, 16S ribosomal DNA, wingless, 28S ribosomal DNA, histone H3). The utility of partitioning the dataset in a manner informed by biological structure and function is demonstrated by comparing various partitioning strategies. In parsimony and partitioned Bayesian analyses of the combined dataset, the castaneum and confusum species groups are supported as monophyletic and as each other's closest relatives. However, a sister group relationship between this clade and Tribolium brevicornis (Leconte 1859) is not supported. Therefore, we suggest transferring brevicornis group species to the genus Aphanotus Leconte (1862). The inferred phylogeny provides an evolutionary framework for comparative studies using flour beetles.

show abstract

Insect appendages and comparative ontogenetics

Cited by 172 publications

References 114 publications

The function of appendage patterning genes in mandible development of the sexually dimorphic stag beetle

The function of appendage patterning genes in mandible development of the sexually dimorphic stag beetle

Structural mouthpart interaction evolved already in the earliest lineages of insects

Relationships among pest flour beetles of the genus Tribolium (Tenebrionidae) inferred from multiple molecular markers

Contact Info

Product

Resources

About