1990
DOI: 10.1016/0924-4247(90)87028-h
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Input and output grating couplers as integrated optical biosensors

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Cited by 17 publications
(8 citation statements)
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“…Using other optical techniques such as grating coupled optical devices (Lukosz et al, 1991) to measure the physisorption of avidin a thickness of 4.2-5.8 nm was measured. More recently, DPI measurements established the thickness of a similar protein, streptavidin, on a biotinylated surface to be 6.1 nm (Cross et al, 2003) and 5.9 nm .…”
Section: Prehybridised Duplex Dnamentioning
confidence: 99%
“…Using other optical techniques such as grating coupled optical devices (Lukosz et al, 1991) to measure the physisorption of avidin a thickness of 4.2-5.8 nm was measured. More recently, DPI measurements established the thickness of a similar protein, streptavidin, on a biotinylated surface to be 6.1 nm (Cross et al, 2003) and 5.9 nm .…”
Section: Prehybridised Duplex Dnamentioning
confidence: 99%
“…The surface plasmon resonance (SPR), created by SPs, can strengthen the localized electromagnetic field tremendously [ 25 , 26 ]. Additionally, SPR is very sensitive to the refractive index attached to the surface of the metal film [ 27 , 28 , 29 ]. The resonance spectral response of the SPR will change when the conditions of the medium are changed, which can reflect certain properties of the system.…”
Section: Principle Of Spr Sensorsmentioning
confidence: 99%
“…Applications of grating couplers in biological and chemical sensing are well known Lukosz et al, 1991;Nellen and Lukosz, 1993;Brandenberg and Gombert, 1993;Clerc and Lukosz, 1997. High sensitivity and real time data analysis Brecht and Gauglitz, 1998 provide the great interest in this type of sensors nowadays.…”
Section: Introductionmentioning
confidence: 99%