Inpatient Costs Associated with Ischemic Heart Disease Among Adults Aged 18-64 Years in the United States

Background Estimates for the average cost of stroke have varied 20-fold in the United States. To provide a robust cost estimate, we conducted a comprehensive analysis of the hospitalization costs for stroke patients by diagnosis status and event type. Methods Using the 2006-2008 MarketScan inpatient database, we identified 97,374 hospitalizations with a primary or secondary diagnosis of stroke. We analyzed the costs after stratifying the hospitalizations by stroke type (hemorrhagic, ischemic, and other strokes) and diagnosis status (primary and secondary). We employed regressions to estimate the impact of event type and diagnosis status on costs while controlling for major potential confounders. Results Among the 97,374 hospitalizations (average cost: $20,396 ± $23,256), the number with ischemic, hemorrhagic, or other strokes was 62,637, 16,331, and 48,208, respectively, with these types having average costs, in turn, of $18,963 ± $21,454, $32,035 ± $32,046, and $19,248 ± $21,703. A majority (62%) of the hospitalizations had stroke listed as a secondary diagnosis only. Regression analysis found that, overall, hemorrhagic stroke cost $14,499 more than ischemic stroke (P <.001). For hospitalizations with a primary diagnosis of ischemic stroke, those with a secondary diagnosis of ischemic heart disease (IHD) had costs that were $9836 higher (P < .001) than those without IHD. Conclusions The costs of hospitalizations involving stroke are high and vary greatly by type of stroke, diagnosis status, and comorbidities. These findings should be incorporated into cost-effective strategies to reduce the impact of stroke.

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“…26 The CCAE data have been used by many researchers to estimate the medical costs of cardiovascular diseases. 27-31 …”

Section: Methodsmentioning

confidence: 99%

Costs of Hospitalization for Stroke Patients Aged 18-64 Years in the United States

Wang

Zhang

Ayala

et al. 2014

Journal of Stroke and Cerebrovascular Diseases

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131

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“…The advantages of using the MarketScan database for economic studies include the large sample, detailed diagnosis codes for medical services, and hospitalization costs that are based on payment to providers [19]. Many researchers have used the MarketScan database to investigate medical costs associated with cardiovascular disease [9,20,21] Using the International Classification of Diseases, 9 th revision (ICD-9) codes, we identified hospitalizations with a primary diagnosis of AMI among patients aged 18-64 years who were enrolled in non-capitated health insurance plans. We further separated the hospitalizations into ST-elevated myocardial infarction (STEMI) and non-ST-elevated myocardial infarction (NSTEMI) cases.…”

Section: Data Sourcementioning

confidence: 99%

“…Surprisingly, however, these cost estimates have not been comprehensively examined in the U.S. Many studies have investigated the economic burden of AMI, but all had some limitations [6][7][8][9][10][11][12][13][14][15][16][17]. Furthermore, in part because of limitations in available studies, the costs of coronary heart disease (CHD) were used in one study to represent the costs for AMI [6], albeit this is inappropriate.…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, in part because of limitations in available studies, the costs of coronary heart disease (CHD) were used in one study to represent the costs for AMI [6], albeit this is inappropriate. For example, a previous study of insured adults aged 18-64 years found that only about 30% of CHD cases represented AMI [9]. Moreover, the American Heart Association recently estimated that the total prevalence of CHD among persons aged ≥20 years was 7% but the AMI prevalence of AMI in this group was 3.1% [2].…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, the American Heart Association recently estimated that the total prevalence of CHD among persons aged ≥20 years was 7% but the AMI prevalence of AMI in this group was 3.1% [2]. In addition, in 2005, hospitalization costs for AMI admissions among adults aged 18-64 years were about $5000 more than those for CHD admissions of non-AMI [9]. Clearly, information on costs that does not clearly distinguish between AMI and non-AMI admissions is of little use in evaluating the cost-effectiveness of interventions to treat AMI [18].…”

Section: Introductionmentioning

confidence: 99%

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Inpatient Costs Associated with Ischemic Heart Disease Among Adults Aged 18-64 Years in the United States

Cited by 3 publications

References 22 publications

Costs of Hospitalization for Stroke Patients Aged 18-64 Years in the United States

Costs of Hospitalization for Stroke Patients Aged 18-64 Years in the United States

Costs of Hospitalizations with a Primary Diagnosis of Acute Myocardial Infarction Among Patients Aged 18-64 Years in the United States

Reducing Smoking in the US Federal Workforce: 5-Year Health and Economic Impacts From Improved Cardiovascular Disease Outcomes

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