Innovative Treatment of Carcinoma ofthe Male Urethra

Ramamurthi, Ravi; Sastry, D.V.L.N.

doi:10.1159/000282794

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…total urethrectomy, penectomy with or without cystoprostatectomy, en‐bloc pubic bone resection and major reconstructive surgery [2–4]. However, the necessity of mutilating radical surgery has been questioned recently for bulbomembranous squamous cell and TCC [14–16]. It has been shown that patients with advanced disease die from metastatic disease and rarely have a local recurrence after surgery [10,15].…”

Section: Discussionmentioning

confidence: 99%

Single‐institution experience with primary tumours of the male urethra

et al. 2008

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OBJECTIVE To assess primary tumours of the urethra in males. PATIENTS AND METHODS We retrospectively reviewed our database from 1986 to 2006 for primary tumours of the male urethra; nine patients with primary tumours of the urethra were analysed and follow‐up information was obtained. RESULTS Three patients had tumours of the prostatic urethra, two of which had proliferating focal inflammation and one a low‐grade, superficial urothelial cancer. All patients were treated successfully with transurethral resection. Six patients had carcinoma of the bulbar or penile urethra, including two with previous local percutaneous radiotherapy for prostate cancer. All had primary surgical excision that was adapted to tumour location and extension. One patient had adjuvant chemotherapy after surgery. All but one patient remain recurrence‐free after a median follow‐up of 20 months. CONCLUSION Primary carcinoma of the male urethra is a rare entity. Previous radiotherapy might be a predisposing factor. Local surgical tumour control is essential for long‐term survival, but the extent of surgery depends on tumour location and stage. Multimodal therapy might be required to obtain an optimum oncological outcome.

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Section: Discussionmentioning

confidence: 99%