Innovative biofilm inhibition and anti-microbial behavior of molybdenum sulfide nanostructures generated by microwave-assisted solvothermal route

Qureshi, Nilam; Patil, Rajendra; Shinde, Manish; Umarji, Govind; Causin, Valerio; Gade, W. N.; Mulik, Uttam; Bhalerao, Anand; Amalnerkar, Dinesh

doi:10.1007/s13204-014-0322-5

Cited by 32 publications

(18 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…36 Other metals that demonstrated some activity in our study have also been previously shown to demonstrate antimicrobial activity. Vanadium based compounds have previously displayed antimicrobial properties in vanadium peroxidase reactions with Streptococcus mutans in planktonic and biolm form.…”

supporting

confidence: 58%

Antimicrobial synergy of cationic grafted poly(para-phenylene ethynylene) and poly(para-phenylene vinylene) compounds with UV or metal ions against Enterococcus faecium

et al. 2018

View full text Add to dashboard Cite

The rise in multidrug resistant bacteria is an area of growing concern and it is essential to identify new biocidal agents. Cationic grafted compounds were investigated for their antimicrobial properties using minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) tests. Synergy testing was carried out using the compounds in the presence of ultraviolet (UV). Fractional inhibitory concentration (FIC) and fractional bactericidal concentration (FBC) tests were carried out using the cationic molecules in conjunction with metal ion solutions of gold, silver, palladium, platinum, rhodium, titanium, tin, vanadium and molybdenum. Individually, the cationic compounds containing quaternary amines, polyphenylene vinylene (PPV) with long polyacrylate grafts (PPV-g-PMETAC (HMw)), polyphenylene ethylene (PPE) with long polyacrylate grafts (PPE-g-PMETAC (HMw)), polyphenylene vinylene (PPV) with short polyacrylate grafts (PPV-g-PMETAC (LMw)) and polyphenylene ethylene (PPE) with short polyacrylate grafts (PPE-g-PMETAC (LMw)) were effective against Enterococcus faecium. The most successful compound under UV was PPV-g-PMETAC (HMw). Following the FICs, palladium and rhodium ion solutions caused a synergistic reaction with all four tested compounds. The presence of conjugated bonds in the cationic molecules increased its antimicrobial activity. These results suggest that the chemical backbone of the compounds, alongside the chain lengths and chain attachment affect the antimicrobial efficacy of a compound. These factors should be taken into consideration when formulating new biocidal combinations.

show abstract

supporting

confidence: 58%

Antimicrobial synergy of cationic grafted poly(para-phenylene ethynylene) and poly(para-phenylene vinylene) compounds with UV or metal ions against Enterococcus faecium

et al. 2018

View full text Add to dashboard Cite

show abstract

“…This principle was adopted for the design and synthesis of molybdenum disulfide (a transition metal dichalcogenide) nanostructures with antimicrobial behavior. [ 129 ] The shape and size of nanomaterials also influence their internalization into bacteria cells. For example, flower‐shaped ZnO nanomaterials that contain more sharp edges and thus more contacting area exhibit more pronounced antimicrobial ability against E. coli and S. aureus than the relatively smoother rod‐ and sphere‐shaped ZnO nanoparticles.…”

Section: Antimicrobial Mechanisms Of Nanometalsmentioning

confidence: 99%

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Makvandi

Wang

Zare

et al. 2020

Adv Funct Materials

442

368

View full text Add to dashboard Cite

Microbial colonization on material surfaces is ubiquitous. Biofilms derived from surface-colonized microbes pose serious problems to the society from both an economical perspective and a health concern. Incorporation of antimicrobial nanocompounds within or on the surface of materials, or by coatings, to prevent microbial adhesion or kill the microorganisms after their attachment to biofilms, represents an important strategy in an increasingly challenging field. Over the last decade, many studies have been devoted to preparing meta-based nanomaterials that possess antibacterial, antiviral, and antifungal activities to combat pathogen-related diseases. Herein, an overview on the state-of-the-art antimicrobial nanosized metal-based compounds is provided, including metal and metal oxide nanoparticles as well as transition metal nanosheets. The antimicrobial mechanism of these nanostructures and their biomedical applications such as catheters, implants, medical delivery systems, tissue engineering, and dentistry are discussed. Their properties as well as potential caveats such as cytotoxicity, diminishing efficacy, and induction of antimicrobial resistance of materials incorporating these nanostructures are reviewed to provide a backdrop for future research.

show abstract

“…An innovative method reported by Yin et al [33] combines photo-and chemotherapy of cancer, using polyethylene glycol (PEG)coated MoS 2 nanosheets as both photothermal agents and drug carriers [33]. Few reports have revealed certain antibacterial capabilities of different MoS 2 nanoforms, affecting pathogen-specific metabolic pathways, causing oxidative and membrane stress [34][35][36].…”

Section: Biological Effects Of Nanoparticles Of Mo Compounds Basic Cymentioning

confidence: 99%

Biological effects of molybdenum compounds in nanosized forms under <i>in vitro</i> and <i>in vivo</i> conditions

Sobańska¹,

Zapór²,

Szparaga³

et al. 2020

Int J Occup Med Environ Health

View full text Add to dashboard Cite

Nanoparticles of transition metal dichalcogenides, particularly of molybdenum (Mo), have gained a lot of focus due to their exceptional physicochemical properties and the growing number of technological applications. These nanoparticles are also considered as potential therapeutic tools, biosensors or drug carriers. It is crucial to thoroughly examine their biocompatibility and ensure safe usage. The aim of this review is to analyze the available data on the biological effects of different nanoforms of elemental Mo and its compounds. In the reviewed publications, different conditions were described, including different experimental models, examined nanoforms, and their used concentrations. Due to these differences, the results are rather difficult to compare. Various studies classify Mo related nanomaterials as very toxic, mildly toxic or non-toxic. Similarly, the mechanisms of toxicity proposed in some studies are different, including oxidative stress induction, physical membrane disruption or DNA damage. Quite promising, however, are the potential medical applications of MoS 2 nanoparticles in therapy of cancer and Alzheimer's disease. Further studies on biocompatibility of nanomaterials based on Mo compounds are warranted.

show abstract

Innovative biofilm inhibition and anti-microbial behavior of molybdenum sulfide nanostructures generated by microwave-assisted solvothermal route

Cited by 32 publications

References 47 publications

Antimicrobial synergy of cationic grafted poly(para-phenylene ethynylene) and poly(para-phenylene vinylene) compounds with UV or metal ions against Enterococcus faecium

Antimicrobial synergy of cationic grafted poly(para-phenylene ethynylene) and poly(para-phenylene vinylene) compounds with UV or metal ions against Enterococcus faecium

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Biological effects of molybdenum compounds in nanosized forms under <i>in vitro</i> and <i>in vivo</i> conditions

Contact Info

Product

Resources

About