Innovative approach for the electrochemical detection of non-electroactive organophosphorus pesticides using oxime as electroactive probe

Dong, Jing; Hou, Juying; Jiang, Junxiang; Ai, Shiyun

doi:10.1016/j.aca.2015.05.033

Cited by 61 publications

(18 citation statements)

References 18 publications

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“…The introduction of GQDs highly improved the electrode surface, and then extend the immobilization value of PAM. Therefore, the oxidation current of PAM clearly raised and the oxidation current of PAM was decreased in the existence of fenthion [45] …”

Section: Electrochemical Carbon Nanodot‐based Sensors and Biosensorsmentioning

confidence: 98%

“…B) The illustrative fabrication process of the pralidoxime (PAM)/GQDs/GCE for organophosphorus pesticides sensing. Adapted from Ref [45] . with permission; Copyright (2015) Elsevier.…”

Section: Electrochemical Carbon Nanodot‐based Sensors and Biosensorsmentioning

confidence: 99%

“…Therefore, the oxidation current of PAM clearly raised and the oxidation current of PAM was decreased in the existence of fenthion. [45]…”

Section: Immobilization Of Various Molecules On the Surface Of Electrmentioning

confidence: 99%

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Carbon Nanodots in Electrochemical Sensors and Biosensors: A Review

et al. 2020

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This Review presents the latest advances in designing electrochemical sensors by using carbon nanodots (CNDs), carbon dots (CDs), and graphene quantum dots (GQDs), as a new class of photoluminescent nanomaterials, which can be employed in a vast number applications, such as biomedicine, biosensing, optical sensing, catalysis, solar cells, imaging, and electrochemical sensing. Recently, the application of CDs and GQDs in electrochemical sensing has increased significantly because of their unique features such as quantum size, excellent biocompatibility, enzyme‐like activity, high active area, and abundance of hydrophilic groups, such as hydroxyl, carboxyl, or amine functionalities. The applications of CDs and GQDs for the electrochemical sensing of hydrogen peroxide, glucose, other organic molecules, as well as metal ions are presented. The utilization of CDs and GQDs for immunosensing and aptasensing is also reported.

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Section: Electrochemical Carbon Nanodot‐based Sensors and Biosensorsmentioning

confidence: 98%

“…B) The illustrative fabrication process of the pralidoxime (PAM)/GQDs/GCE for organophosphorus pesticides sensing. Adapted from Ref [45] . with permission; Copyright (2015) Elsevier.…”

Section: Electrochemical Carbon Nanodot‐based Sensors and Biosensorsmentioning

confidence: 99%

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Carbon Nanodots in Electrochemical Sensors and Biosensors: A Review

et al. 2020

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“…Taking advantage of the good reactivity between oximes and OP compounds, Dong et al. 99 immobilized PAM on graphene quantum dot (GQDs). The introduction of GQDs significantly increased the effective electrode area which leads to increased immobilization of PAM.…”

Section: Electrochemical Detection Of Nerve Agentmentioning

confidence: 99%

Recent Advances in Electrochemical Sensors for Detecting Weapons of Mass Destruction. A Review

Singh

2016

Electroanalysis

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1IntroductionChemical warfare agents (CWA) are toxic chemicals which have been deliberately used since World WarI [1]. Along with biological and nuclear threats;t hese weapons have become some of the most feared and least predictable mass destruction agentso nt he battlefield and in the hands of terrorists.A mong CWA, nerve agents,o ften organophosphates (OP), are ac lass of lethal weapons of mass destruction (WMD) that kill mankind by disrupting the nerve transfer mechanism [2][3].T he extreme toxicity of OP compounds is attributed to the inhibitiono ft he enzyme acetylcholinesterase (AChE)b yc ovalently blocking the active site of the enzyme which leadstoaccumulation of acetylcholine causing cholinergic over stimulation, culminating in death causedb yr espiratory failure [4].A n example of their potency, sarin was released by terrorists in aT okyo subways tation in 1995, resulting in more than 5000 humancasualties [5].Unfortunately,these highly adhesive and volatile nerve agents are colorless,o dorless and tasteless,m aking detection very difficult. Thed etermination of OP or nervea gents has become increasingly important for soldiers in war fielda sw ell as civilians due to the upsurge in terrorist activity [6].E arly detection of these noxiousO Pn eurotoxins is imperative for protecting water resources and food supplies,i nt he defense against terrorist activity,a nd for monitoring detoxification processes [6].C urrently,t here are many laboratory-based conventional analytical detection techniques for detecting OP compounds such as gas chromatography,h igh performance liquid chromatography,l iquidc hromatograph with mass spectrometer (LC-MS), and nuclear magnetic resonance (NMR) spectrometer [7][8][9][10].H owever, these techniques are time-consuming and expensive, non-portable and require aq ualified and experienced staff,a nd cannot be used for continuous monitoring [11][12][13][14].C onsidering the urgency of the situationt he CWAm ay cause,c ombatant therefore needs portable,e asiness of operation and ability to precisely detect thesea gents in real war field conditions.T he rapidd etection of WMD is also of pivotal importancet oh omelands ecurityi nt erms of responding to or recovering from the worst possible terrorist attack. Recent insights into the development of smart sensors and resultant analytical systems that are portable,l ightweight, accuratea nd low cost able to augmentt he use of these sensors onsite,t herebyp roviding added dimensions of rich,a nalyticali nformation to the combatant in at imely manner.T herefore,asimple and rapid yet reliable nerve agent detection warning system is critically desirable in the current climate of terrorism awareness.This review describes documented currentand developing technologies for electrochemical detection and identificationo fCWA and addresses the challenges associated with CWAd etection in complex sample matrices.H erein, we address sed about the electrochemical methodologies based on enzymatic and non-enzymatic principals for detection of nerve agents...

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“…Ai et al. described an oxime‐based electrochemical sensor for non‐electroactive OPs determination by using pralidoxime (PAM) as the electroactive probe and for fenthion with a detection limit of 6.8×10 −12 M . In recent years, due to superior properties of electrochemical methods such as low cost, simple preparation and high sensitivity take attention as alternative technique for detection of OPs.…”

Section: Introductionmentioning

confidence: 99%

Metallophthalocyanines Bearing Polymerizable {[5‐({(1E)‐[4‐(Diethylamino)phenyl]methylene}amino)‐ 1‐naphthy1]oxy} Groups as Electrochemical Pesticide Sensor

2017

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The synthesis and characterization of novel metallophthalocyanines (MPcs(ea)) carrying {[5‐({(1E)‐[4‐(diethylamino)phenyl]methylene}amino)‐1‐naphthyl]oxy} groups on four peripheral positions have been reported. These complexes have been characterized by a combination of FT‐IR, 1H and 13C NMR, mass and UV‐Vis spectroscopy techniques. Redox active metal centers in the core of the Pc rings (Co (II) [CoPc(ea)], Mn(III) [Cl–MnPc(ea)], and Ti(IV)O [TiOPc(ea)]) and electropolymerizable substituents on the peripheral positions of Pc rings were used to increase redox activity and electrochemically polymerization ability of the complexes. The redox properties of MPcs(ea) were determined with voltammetry and in situ spectroelectrochemistry techniques. Then, GCE/MPc(ea) electrodes were constructed with the electropolymerization of MPcs and these electrodes were tested as the pesticide sensors. Sensing studies indicated that type of the metal center of the complexes effectively influenced the sensing activities. While all complexes showed interaction abilities for the fenitrothion, parathion and eserine, GCE/CoPc(ea) electrode detected the parathion selectively with LOD value of 4.52×10−7 mol dm−3 among studied three pesticides. Moreover, GCE/MnClPc(ea) electrode selectively detected eserine with LOD value of 6.43×10−7 mol dm−3 and GCE/TiOPc(ea) electrode detected parathion with LOD value of 8.64×10−7 mol dm−3. All GCE/MPcs(ea) electrodes showed high sensitivity and wide linear ranges for those pesticides. These sensing data illustrated the usability of these modified electrodes in real samples such as seawater with good selectivity and sensitivity.

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Innovative approach for the electrochemical detection of non-electroactive organophosphorus pesticides using oxime as electroactive probe

Cited by 61 publications

References 18 publications

Carbon Nanodots in Electrochemical Sensors and Biosensors: A Review

Carbon Nanodots in Electrochemical Sensors and Biosensors: A Review

Recent Advances in Electrochemical Sensors for Detecting Weapons of Mass Destruction. A Review

Metallophthalocyanines Bearing Polymerizable {[5‐({(1E)‐[4‐(Diethylamino)phenyl]methylene}amino)‐ 1‐naphthy1]oxy} Groups as Electrochemical Pesticide Sensor

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