The international flow of highly skilled workers has a large effect on any country. Simultaneously, innovation and its constituent elements allow increasing growth in a sustainable way. This paper analyses the impact of the most important constituent elements of innovation found in literature on immigration of highly skilled workers. In order to do that, we performed a cluster analysis of 182 countries (OECD and non-OECD members), which are net exporters of highly skilled immigrants, and 25 receiving countries members of the OECD. It includes a detailed discussion of results by world regions including examples of specific programmes and policies for each variable of the study. Overall, our results confirm that the attraction of international talent is related to both the constituent elements of innovation and the level of economic growth. In this regard, countries like the U.S., Australia, Canada and the United Kingdom are among the main destinations of highly skilled immigrants of any region of origin due to the implementation of policies that favor the development of innovation.However, access restrictions for highly skilled workers would limit the effects of those policies. Therefore, in the design of strategies for attracting talent, the qualification of such workers should take precedence over their country of origin, thus encouraging greater innovation activities among those highly skilled immigrants.