Initial investigations of scatter cross-talk in simultaneous biplane high-speed 1000 frames per second neuro-angiography using Monte Carlo simulations

Troville, Jonathan; Dhonde, Rushikesh S.; Shields, Allison; Rudin, Stephen; Bednarek, Daniel R.

doi:10.1117/12.2612951

Cited by 2 publications

(3 citation statements)

References 11 publications

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“…Additionally, the high frame-rate potential of PCDs (up to 1000 fps) was not investigated for dynamic imaging sequences such as fluoroscopy and DSA, rather, static images were acquired to demonstrate the advantages of the PCD over the EID. Other works have demonstrated the potential of high-frame-rate PCD for angiographic imaging (Krebs et al 2019 , Nagesh et al 2022a , 2022b , Troville et al 2022 , Williams et al 2022 , Wu et al 2022 ), and our future work will follow in these footsteps to further characterize the benefits of PCDs for interventional imaging applications. Furthermore, the proof-of-concept image quality matching between the PCD and EID in this work was only done with static post-log images rather than pre-log images or dynamic image sequences such as those that would be acquired during conventional fluoroscopy, and the weighting factors for the LE and HE images to match the EID signal and contrast were empirically determined.…”

Section: Discussionmentioning

confidence: 90%

“…Prior works have investigated the use of PCDs to improve the imaging utility of C-arms for interventional imaging tasks: A PCD capable of a high frame rate of 1000 Hz has been investigated for high-speed angiography applications including quantification of blood velocity (Krebs et al 2019 , Nagesh et al 2022a , 2022b , Troville et al 2022 , Williams et al 2022 , Wu et al 2022 ). Other works have directly implemented a PCD with a clinical C-arm gantry: One approach was to piggyback mount a PCD in front to the existing FPD (Ahmad et al 2016 , Müller et al 2016 , Ahmad et al 2017 ) for dual-energy 2D and 3D imaging with a full-width beam collimation.…”

Section: Introductionmentioning

confidence: 99%

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Photon counting-energy integrating hybrid flat panel detector systems for image-guided interventions: an experimental proof-of-concept

Treb

Haemisch²,

Ullberg

et al. 2023

Phys. Med. Biol.

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Objective: Current C-arm x-ray systems equipped with scintillator-based flat panel detectors (FPDs) lack sufficient low-contrast detectability and spectral, high-resolution capabilities much desired for certain interventional procedures. Semiconductor-based direct-conversion photon counting detectors (PCDs) offer these imaging capabilities, although the cost of full field-of-view (FOV) PCD is still too high at the moment. The purpose of this work was to present a hybrid photon counting-energy integrating flat panel detector design as a cost-effective solution to high-quality interventional imaging. Approach: In the proposed hybrid detector design, the central scintillator and thin-film transistor elements in the FPD are replaced with a semiconductor PCD module to upgrade the imaging capabilities of the C-arm system while preserving the full FOV coverage. The central PCD module can be used for high-quality 2D and 3D region-of-interest imaging with improved spatial- and temporal-resolution as well as spectral resolving capability. An experimental proof-of-concept was conducted using a 30x2.5 cm^2 CdTe PCD and a 40x30 cm^2 CsI(Tl)-aSi(H) FPD. Main Results: Phantom and in vivo animal studies show 1) improved visualization of small stent wires in both 2D and 3D images due to the better spatial resolution of the PCD; 2) dual-energy angiography imaging capability by using the spectral PCD; 3) better conspicuity of small peripheral iodinated vessels (contrast-to-noise ratio improvement range: [29%, 151%]); 4) the central PCD outputs can be fused seamlessly with the surrounding scintillator detector outputs to provide full field imaging: a post-processing chain was developed by leveraging the PCD's spectral information to match the image contrast of PCD images to the surrounding scintillator detector, followed by spatial filtering of the PCD image to match noise texture and spatial resolution. Significance: The hybrid FPD design provides a cost-effective option to upgrade C-arm systems with spectral and ultra-high resolution capabilities without interfering with the clinical need for full FOV imaging.

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Section: Discussionmentioning

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Photon counting-energy integrating hybrid flat panel detector systems for image-guided interventions: an experimental proof-of-concept

Treb

Haemisch²,

Ullberg

et al. 2023

Phys. Med. Biol.

View full text Add to dashboard Cite

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“…Even though the biplane acquisitions were simultaneous, cross scatter was not an issue with this setup but could be a consideration if a full head phantom were used. 4 The benchtop detector setup is shown in Figure 8.…”

Section: High-speed Detectormentioning

confidence: 99%

Multi-angled simultaneous biplane High-Speed Angiography (HSA) of patient-specific 3D-printed aneurysm phantoms using 1000 fps CdTe Photon-Counting Detectors (PCD’s )

Vanderbilt

Shields

et al. 2023

Medical Imaging 2023: Biomedical Applications in Molecular, Structural, and Functional Imaging

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1000 fps HSA enables visualization of flow details, which may be important in accurately guiding interventional procedures; however, single-plane imaging may lack clear visualization of vessel geometry and flow detail. The previously presented high-speed orthogonal biplane imaging may overcome these limitations but may still result in foreshortening of vessel morphology. In certain morphologies, acquiring two non-orthogonal biplane projections at multiple angles can provide better flow detail rather than a standard orthogonal biplane acquisition. Flow studies of aneurysm models were performed, where simultaneous biplane acquisitions at various angles separating the two detector views allowed for better evaluation of morphology and flow. 3D-printed, patient-specific internal carotid artery aneurysm models were imaged with various non-orthogonal angles between the two high-speed photon-counting detectors (7.5 cm x 5 cm FOV) to provide frame-correlated simultaneous 1000-fps image sequences. Fluid dynamics were visualized in multi-angled planes of each model using automated injections of iodine contrast media. The resulting dual simultaneous frame-correlated 1000-fps acquisitions from multiple planes of each aneurysm model provided improved visualization of complex aneurysm geometries and flow streamlines. Multi-angled biplane acquisitions with frame correlation allows for further understanding of aneurysm morphology and flow details: additionally, the ability to recover fluid dynamics at depth enables accurate analysis of 3D flow streamlines, and it is expected that multiple-planar views will enable better volumetric flow visualization and quantification. Such better visualization has the potential to improve interventional procedures.

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Initial investigations of scatter cross-talk in simultaneous biplane high-speed 1000 frames per second neuro-angiography using Monte Carlo simulations

Cited by 2 publications

References 11 publications

Photon counting-energy integrating hybrid flat panel detector systems for image-guided interventions: an experimental proof-of-concept

Photon counting-energy integrating hybrid flat panel detector systems for image-guided interventions: an experimental proof-of-concept

Multi-angled simultaneous biplane High-Speed Angiography (HSA) of patient-specific 3D-printed aneurysm phantoms using 1000 fps CdTe Photon-Counting Detectors (PCD’s )

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