Initial Clinical Experience: Symmetric-Tip Dialysis Catheter with Helical Flow Characteristics Improves Patient Outcomes

Clark, Timothy W.I.; Redmond, John; Mantell, Mark P.; Nadolski, Gregory J.; Mondschein, Jeffrey I.; Dowd, Michael F.; Dagli, Mandeep; Sudheendra, Deepak; Shlansky-Goldberg, Richard D.; Cohen, Raphael M.

doi:10.1016/j.jvir.2015.06.033

Cited by 13 publications

(20 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The structure of the tip of the catheter can damage the wall of blood vessels resulting in platelet aggregation and thrombosis formation 13 . In another study 10 , after 4 months of follow-up of two groups of hemodialysis patients who received VectorFlow or Ash Split Cath, it was found that significantly higher percentage of CevtorFlow catheters (about 90%) were patent when compared to the other group (45%). In a study 11 that followed hemodialysis patients for three months, it was shown that VectorFlow was a safe and effective catheter in these patients with no acute complications.…”

Section: Discussionmentioning

confidence: 95%

“…Previous studies reported efficacy of the Palindrome catheter 4,9 . The VectorFlow catheter for use in hemodialysis patients was cleared by the FDA (Food and Drug Administration) in 2014 10 . Although designs of the tips in the VectorFlow and Palindrome catheters are symmetrical, in the Vector-Flow, low flow rate in side the holes by helical flowdeflecting interfaces with less shear-induced platelet activation 11 with separate arterial and venous apertures.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of the efficacy of two types of hemodialysis catheters: the VectorFlow vs. Palindrome catheters

Ali

Sobhiyeh

2019

Biomed. Res. Ther.

View full text Add to dashboard Cite

Introduction: Permanent vascular access via catheters is a critical factor for patients who need long-term hemodialysis. Differences in the design and mechanical factors can affect efficacy and survival of the permanent catheters. Modifications in the designs of the catheters can decrease the likelihood of damaging blood vessels as well as thrombosis formation and malfunction of the catheters. Objective: To compare survival of VectorFlow, complete symmetry of distal tip and offsetting of its side holes, with those of Palindrome, a complete symmetrical catheter. Methods: In this study, 146 CKD (chronic kidney disease) patients who required chronic hemodialysis were divided into VectrFlow (76 subjects) and Palindrome (70 subjects) catheter groups. The patients were followed for six months and the survival rate in each group was determined. Results: Mean (+/-SD) survival time in the VectorFlow catheter group (6.55+/-3.88 months, 2 to 24 months) was longer than in the Palindrome catheter group (5.22+/-2.88 months, one to 13 months). After six months, the VectorFlow catheter group (40 cases, 54.8%) had a higher number of patients, having a functioning catheter in place than the Palindrome group (26 cases, 382%); P= 0.04. Conclusion: The VectorFlow hemodialysis catheter had a better survival rate after 6 months when compared to the Palindrome catheter. We recommend using this catheter in CKD patients, who require a long-term permanent catheter.

show abstract

Section: Discussionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

Comparison of the efficacy of two types of hemodialysis catheters: the VectorFlow vs. Palindrome catheters

Ali

Sobhiyeh

2019

Biomed. Res. Ther.

View full text Add to dashboard Cite

show abstract

“…A randomized comparison of split‐tip vs. step‐tip HD catheters showed similar blood flows and better survival of split‐tip catheters . A symmetric‐tip catheter in another study showed similar blood flow, but better survival than the split‐tip catheter at 120 days . Left sided IJ dialysis catheters generally have shorter survival than right sided catheters .…”

Section: Discussionmentioning

confidence: 98%

“…10 A symmetric-tip catheter in another study showed similar blood flow, but better survival than the split-tip catheter at 120 days. 11 Left sided IJ dialysis catheters generally have shorter survival than right sided catheters. 6 A 2-month follow-up study of a symmetric-tip catheter showed similar blood flow but lower catheter dysfunction rate, lower recirculation with reversed blood lines and higher short-term catheter survival rate vs. a step-tip catheter.…”

Section: Discussionmentioning

confidence: 99%

Maintenance of blood flow rate on dialysis with self‐centering CentrosFLO catheter: A multicenter prospective study

Agarwal

Ash

2016

Hemodialysis International

View full text Add to dashboard Cite

Introduction Chronic central venous catheters (CVC) for dialysis lose patency and deliver lower blood flow over time, often due to fibrous sheathing that covers the lumen tips. The CentrosFLO central venous catheter has a shape that directs the arterial and venous tips away from the walls of the vena cava and right atrium, making sheathing of the tips less likely. Methods A prospective, multicenter, single arm, non-controlled, observational study was conducted at eight sites in the United States. All consenting dialysis patients receiving CentrosFLO catheters through the right or left internal jugular veins were accepted in the study, as long as the catheter was expected to be used for 45 days and was not an over-the-wire replacement for a previous CVC. Data were automatically collected on initial and average dialysis blood flow rate and initial arterial and venous pressures, for up to 26 weeks of dialysis therapy. Findings 75 patients were enrolled. KaplanMeier analysis indicated that 87% of patients maintained blood flow rate over 300 mL/min throughout 26 weeks of follow-up. There was no decline in average dialysis blood flow rate and no significant change in hydraulic resistance of the arterial or venous lumens of the catheters during the study. Discussion The CentrosFLO catheter demonstrates long term patency with good flow rates on dialysis, which, by comparison with previous studies, shows a clinically significant improvement in blood flow rate vs. other catheters. Stable hydraulic resistance of the catheter lumens showed no evidence of tip encroachment by fibrous sheaths.

show abstract

“…Other symmetric-tip CVCs have been introduced into the market with distal lumens that are angled and on opposing sides of the catheter so that blood exiting the venous port is deflected away from blood entering the arterial port of the catheter. This latter design may reduce platelet activation during the high-flow conditions of dialysis (27,29) and potentially result in longer catheter patency from significantly lower rates of thrombosis (30).…”

Section: Lumen and Tip Design Of Long-term Cvcsmentioning

confidence: 99%

Clinical and Regulatory Considerations for Central Venous Catheters for Hemodialysis

Silverstein

Trerotola

Clark

et al. 2018

CJASN

View full text Add to dashboard Cite

Central venous catheters remain a vital option for access for patients receiving maintenance hemodialysis. There are many important and evolving clinical and regulatory considerations for all stakeholders for these devices. Innovation and transparent and comprehensive regulatory review of these devices is essential to stimulate innovation to help promote better outcomes for patients receiving maintenance hemodialysis. A workgroup that included representatives from academia, industry, and the US Food and Drug Administration was convened to identify the major design considerations and clinical and regulatory challenges of central venous catheters for hemodialysis. Our intent is to foster improved understanding of these devices and provide the foundation for strategies to foster innovation of these devices.

show abstract

Initial Clinical Experience: Symmetric-Tip Dialysis Catheter with Helical Flow Characteristics Improves Patient Outcomes

Cited by 13 publications

References 16 publications

Comparison of the efficacy of two types of hemodialysis catheters: the VectorFlow vs. Palindrome catheters

Comparison of the efficacy of two types of hemodialysis catheters: the VectorFlow vs. Palindrome catheters

Maintenance of blood flow rate on dialysis with self‐centering CentrosFLO catheter: A multicenter prospective study

Clinical and Regulatory Considerations for Central Venous Catheters for Hemodialysis

Contact Info

Product

Resources

About