Abstract:Introduction: Permanent vascular access via catheters is a critical factor for patients who need long-term hemodialysis. Differences in the design and mechanical factors can affect efficacy and survival of the permanent catheters. Modifications in the designs of the catheters can decrease the likelihood of damaging blood vessels as well as thrombosis formation and malfunction of the catheters.
Objective: To compare survival of VectorFlow, complete symmetry of distal tip and offsetting of its side holes, … Show more
“…There is contradictory literature regarding the uptake of nanoparticles as a function of their zeta potential which may result from the use of different cell models and/or conditions. [83][84][85][86][87][88] It should also be noted that the ChemLinked-HAuNS and the corresponding monomers had lower cytotoxicities than citrate stabilized HAuNS, whose cell viability was lower than 75% at a concentration as low as OD = 0.5, as reported previously by us using the same 2H11 murine endothelial cell line. 89 The added surface negative charge may indeed cause higher uptake by this cell line under our conditions of evaluation.…”
Section: Cytotoxicity Evaluation Of Linked-haunssupporting
We report a versatile methodology to covalently link hollow gold nanoshells (HAuNS) through modular design of multi-tasking ligands and bio-adaptable chemistry. The biocompatible ligand composition includes strategically placed two polyethylene...
“…There is contradictory literature regarding the uptake of nanoparticles as a function of their zeta potential which may result from the use of different cell models and/or conditions. [83][84][85][86][87][88] It should also be noted that the ChemLinked-HAuNS and the corresponding monomers had lower cytotoxicities than citrate stabilized HAuNS, whose cell viability was lower than 75% at a concentration as low as OD = 0.5, as reported previously by us using the same 2H11 murine endothelial cell line. 89 The added surface negative charge may indeed cause higher uptake by this cell line under our conditions of evaluation.…”
Section: Cytotoxicity Evaluation Of Linked-haunssupporting
We report a versatile methodology to covalently link hollow gold nanoshells (HAuNS) through modular design of multi-tasking ligands and bio-adaptable chemistry. The biocompatible ligand composition includes strategically placed two polyethylene...
“…2c), confirming the effective uptake of IR820@ZIF-8, 41 potentially owing to the positively charged nature of NPs. 42 The normal macrophages also demonstrated a time-dependent uptake of NPs. Nonetheless, the internalization of IR820@ZIF-8 in RAW264.7 cells was significantly lower than activated foam cells at each of the time points (Fig.…”
Section: Cellular Uptake and Cytotoxicity Of Zif-8mentioning
Atherosclerosis (AS) is a condition associated with dysfunctional lipid metabolism and an inflammatory immune microenvironment that remains the leading cause of severe cardiovascular events. Drugs exhibiting both anti-inflammatory and lipid-scavenging...
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