Inhibitory effect of Plant Essential Oils on Malassezia pachydermatis

Lee, Jeong‐Hyun; Lee, Jae-Sug

doi:10.3839/jabc.2010.033

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…Essential oils and volatile compounds are plant second ary metabolites that have a wide range of applications in the environment, foods, and human products (8,13,15,21,28). A number of studies have reported acaricidal effects of natural products and their constituents (15,23).…”

Section: Resultsmentioning

confidence: 99%

Food Protective Effects of Periploca sepium Oil and Its Active Component against Stored Food Mites

Jeong

Cho

Lee

2012

Journal of Food Protection

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The aim of this study was to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae. Based on its 50% lethal dose (LD(50) ) value, P. sepium oil (8.45 μg/cm(2)) was highly active against T. putrescentiae. The active constituent of P. sepium was isolated by chromatographic techniques and identified as 2-hydroxy-4-methoxybenzaldehyde. In the comparison with synthetic acaricides, the acaricidal activity of 2-hydroxy-4-methoxybenzaldehyde (0.94 μg/cm(2)) against T. putrescentiae was 12.2- and 31.2-fold greater than those of benzyl benzoate (11.45 μg/cm(2)) and N,N-diethyl-m-toluamide (29.33 μg/cm(2)), respectively. To establish structure-activity relationships, the acaricidal activities of 2-hydroxy-4-methoxybenzaldehyde and its derivatives against T. putrescentiae were determined by using an impregnated fabric disk bioassay. On the basis of LD(50) values, 4-methoxybenzaldehyde (0.48 μg/cm(2)) was the most effective against T. putrescentiae, followed by 3-methoxybenzaldehyde (0.82 μg/cm(2)), 2-hydroxy-5-methoxybenzaldehyde (0.92 μg/cm(2)), 2-methoxybenzaldehyde (0.95 μg/cm(2)), 2-hydroxybenzaldehyde (0.97 μg/cm(2)), and 2-hydroxy-3-methoxybenzaldehyde (2.35 μg/cm(2)). These results indicate that the introduction of a hydroxyl and/or methoxy group into the benzaldehyde skeleton increased the acaricidal activity. Therefore, 2-hydroxy-4-methoxybenzaldehyde and its derivatives could potentially be used as potent mite control agents.

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Section: Resultsmentioning

confidence: 99%

Food Protective Effects of Periploca sepium Oil and Its Active Component against Stored Food Mites

Jeong

Cho

Lee

2012

Journal of Food Protection

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Atividade antifúngica do óleo essencial de Origanum vulgare frente a Malassezia pachydermatis

Santin

Giordani

Madrid

et al. 2014

Arq. Bras. Med. Vet. Zootec.

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 RESUMOObjetivou-se com este estudo avaliar a atividade antifúngica in vitro do óleo essencial de Origanum vulgare frente a isolados clínicos de Malassezia pachydermatis. As folhas secas de O. vulgare foram adquiridas de distribuidor comercial com certificado de qualidade e origem e encaminhadas para extração do óleo essencial e cromatografia. Para realização do teste in vitro, foi utilizada a técnica de microdiluição em caldo (CLSI M27A3) com modificações para fitofármacos e M. pachydermatis. O óleo essencial de orégano foi testado nas concentrações de 28 a 0,87mg/mL diluído em caldo Sabouraud com 1% de tween 80. Todos os isolados foram testados em duplicata. Na análise cromatográfica do óleo essencial, foram identificados 12 compostos, sendo timol, -terpineno e 4-terpineol os compostos majoritários. A CIM e a CFM dos 42 isolados de M. pachydermatis variaram de ≤0,87 a 7mg/mL, com valores de CIM 50 e CIM 90 de 1,18 e 3,28mg/mL, respectivamente. Com este estudo foi possível concluir que M. pachydermatis é sensível ao óleo essencial de orégano mesmo em concentrações baixas. Dessa maneira, o óleo essencial de orégano apresenta-se como promissor na bioprospecção de novos fármacos para o tratamento das otites e dermatites na clínica de pequenos animais.Palavras-chave: cão, extratos vegetais, leveduras, orégano, suscetibilidade ABSTRACT The aim of this study was to evaluate the in vitro antifungal activity of essential oil of

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Inhibitory effect of Plant Essential Oils on Malassezia pachydermatis

Cited by 2 publications

References 8 publications

Food Protective Effects of Periploca sepium Oil and Its Active Component against Stored Food Mites

Food Protective Effects of Periploca sepium Oil and Its Active Component against Stored Food Mites

Atividade antifúngica do óleo essencial de Origanum vulgare frente a Malassezia pachydermatis

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