Inhibition of mineral loss at the enamel/sealant interface of fissures sealed with fluoride- and non-fluoride containing dental materials<i>in vitro</i>

Kantovitz, Kamila Rosamilia; Pascon, Fernanda Miori; Correr, Gisele Maria; Borges, Ana Flávia Sanches; Uchôa, Marinês Nobre Dos Santos; Puppin-Rontani, Regina Maria

doi:10.1080/00016350600856208

Cited by 19 publications

(5 citation statements)

References 27 publications

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“…An in vitro study conducted by Kantovitz et al 13 aimed to test the enamel mineral loss inhibition ability at the enamel/sealant interface by fluoride-containing (both GIC- and resin-based) and nonfluoride-containing sealants. The results demonstrated that resin sealant did not prevent enamel mineral loss, contrary to GIC, which showed the highest capacity for fluoride release.…”

Section: Discussionmentioning

confidence: 99%

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Ability of Pit and Fissure Sealant-containing Amorphous Calcium Phosphate to inhibit Enamel Demineralization

Zawaideh¹,

Owais²,

Kawaja³

2016

International Journal of Clinical Pediatric Dentistry

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Aim: To evaluate the effect of amorphous calcium phosphate (ACP)-containing pit and fissure sealant on inhibition of enamel demineralization in vitro.Materials and methods: Enamel specimens (n = 75) were prepared using freshly extracted noncarious human third molars. Box-shaped cavities (8 × 2 × 2 mm) on the buccal or lingual surfaces were prepared and restored with resin-based sealant (Concise™), ACP-containing sealant (Aegis®) or fluoride-containing sealant (Conseal-F™). The samples were acid challenged in a demineralizing solution of 50 mmol/l lactic acid at pH 5.0 for 4 days. The change in enamel microhardness (ASuH) was calculated. Data were analyzed using one-way analysis of variance (ANOVA) and Tukey’s post hoc test.Results: The mean SuH0 (±SD) (in Vicker’s unit) prior to the acid challenge was: Concise™ (318.83 ± 33.86), Aegis® (331.03 ± 21.52), Conseal-F™ (310.12 ± 34.31). Following the acid challenge, the values dropped in all groups and ASuH (±SD) values were 269.17 ± 47.49, 151.39 ± 23.96 and 175.79 ± 32.39 respectively.Conclusion: The ACP-containing pit and fissure sealant has the potential to inhibit enamel demineralization.How to cite this article: Zawaideh FI, Owais AI, Kawaja W. Ability of pit and fissure sealant-containing amorphous calcium phosphate to inhibit enamel demineralization. Int J Clin Pediatr Dent 2016;9(1):10-14.

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Section: Discussionmentioning

confidence: 99%

“…They concluded that the presence of fluoride in a material’s composition per se does not indicate its capability to prevent the development of enamel caries-like lesions. 13 …”

Section: Discussionmentioning

confidence: 99%

Ability of Pit and Fissure Sealant-containing Amorphous Calcium Phosphate to inhibit Enamel Demineralization

Zawaideh¹,

Owais²,

Kawaja³

2016

International Journal of Clinical Pediatric Dentistry

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“…The introduction of fluoride-releasing sealants has widen the perspectives in the prevention of pit and fissure caries 21 . Fluoride-releasing materials can provide benefits in areas near to the sealant margins where the acid challenge may result in enamel demineralization 10 . In addition, the anticariogenic effect of fluoride-releasing fissure sealants depends on the amount of released fluoride, but obviously even more on the longevity of this release 5 .…”

Section: Introductionmentioning

confidence: 99%

“…In addition to traditional fluoride-releasing resin sealants 13 , other fluoride-releasing materials have been used as fissure sealants, such as conventional glass ionomer cements (GICs) 10 and resin-modified GICs (RMGICs) 13 . These materials should provide constant fluoride release for a prolonged period of time and act as a reservoir of fluoride ion in order to promote fluorapatite formation in enamel 9 .…”

Section: Introductionmentioning

confidence: 99%

Influence of environmental conditions on properties of ionomeric and resin sealant materials

et al. 2009

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Objectives:The aim of this study was to determine the effect of environmental conditions on the degradation of ionomeric and resin sealant materials.Material and Methods:FluroShield, Vitremer, and Ketac Molar disc-shaped specimens (n=18/material) were prepared, polished, subjected to initial hardness and roughness readings. Six discs of each material were randomly assigned to one of three different storage solutions: 0.3% citric acid (CA), demineralization solution (DE), and remineralization solution (RE). The specimens were individually immersed in 3 mL of the test solutions, which were daily changed. After 15 days of storage, new surface roughness and hardness readings were done. Fluoride release in the solutions was measured within 15 days. Data were analyzed by ANOVA and Tukey's and Contrast tests (α=0.05).Results:The storage in CA increased the roughness of Vitremer and Ketac Molar. A significant reduction in hardness was observed for all materials after storage in all solutions. For all materials, the greatest amounts of fluoride release occurred during the 1st day. FluroShield presented the same patterns of fluoride release in all solutions. Ketac Molar and Vitremer released the highest amounts of fluoride in the CA solution.Conclusions:Ionomeric materials are more susceptible to degradation than resin-based materials under acidic conditions. Acidic conditions lead to a higher fluoride release from ionomeric materials.

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“…Furthermore, these materials together with compomers are known to release fluoride 19 , 25 . Vitremer RMGIC has been reported to release higher amounts of fluoride than conventional GICs 11 , 14 . Indeed, the release of fluoride has been suggested to be the cause of toxicity of GICs 10 .…”

Section: Discussionmentioning

confidence: 99%

Toxicity Testing of Restorative Dental Materials Using Brine Shrimp Larvae (Artemia salina)

2008

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This study investigated the effect of extracts of different composites, glass ionomer cement (GIC)s and compomers on the viability of brine shrimp larvae. Ethanolic extracts of four dental composites (Z-100; Solitaire 2; Filtek P60 and Synergy), a conventional GIC (Ketac-Fil), a resin-modified glass ionomer cement (Vitremer), two compomers (F2000; Dyract AP), and a flowable compomer (Dyract Flow) were prepared from each material. Following evaporation of the ethanol, the extracts were resuspended in distilled water, which was then used to test the effects on the viability of brine shrimp larvae. For the composites, the extract of Synergy was the least toxic (88% viability) followed by the extracts of Solitaire 2, Z100 and P60 (75%, 67.5% and 50% viability, respectively). One-way ANOVA revealed highly significant differences between the resin composite materials (p<0.001). Follow-up comparison between the composite groups by Tukey's pairwise multiple-comparison test (α =0.05) showed that the extract of Synergy was significantly less toxic than the extracts of all the other materials except that of Solitaire 2. The compomers showed 100% lethality, while the percentage of viable larvae for the extracts of Ketac-Fil, and Vitremer were 32.3%, and 37.0%, respectively. One-way ANOVA revealed highly significant differences between the groups of materials (p<0.001). Follow-up comparison between the groups by Tukey's test (α = 0.05) showed that the toxic effect of the extracts of the compomers were significantly greater than that of Ketac-Fil, and Vitremer. The differences in the toxic effects of Vitremer and Ketac-Fil were not statistically significant. In conclusion, the toxicity of composite materials varied according to their chemical composition. Compomers were the most lethal materials to brine shrimp larvae followed by GICs and then composites.

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Inhibition of mineral loss at the enamel/sealant interface of fissures sealed with fluoride- and non-fluoride containing dental materialsin vitro

Cited by 19 publications

References 27 publications

Ability of Pit and Fissure Sealant-containing Amorphous Calcium Phosphate to inhibit Enamel Demineralization

Ability of Pit and Fissure Sealant-containing Amorphous Calcium Phosphate to inhibit Enamel Demineralization

Influence of environmental conditions on properties of ionomeric and resin sealant materials

Toxicity Testing of Restorative Dental Materials Using Brine Shrimp Larvae (Artemia salina)

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