Inhibition of gastric acid secretion by a standardized aqueous extract of Cecropia glaziovii Sneth and underlying mechanism

Souccar, Caden; Cysneiros, Roberta Monterazzo; Tanae, Mirtes Midori; Torres, Luce Maria Brandão; Lima‐Landman, Maria Teresa R.; Lapa, Antônio José

doi:10.1016/j.phymed.2008.02.006

Cited by 40 publications

(31 citation statements)

References 35 publications

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“…Several biological effects were described in the literature for C. glaziovii such as antihypertensive (LimaLandmann et al, 2007;Ninahuaman et al, 2007), anxiolytic and antidepressant (Rocha et al, 2002;, bronchodilator (Delarcina et al, 2007), antiacid secretion and antiulcer (Souccar et al, 2008).…”

Section: Pharmaceutical Biologymentioning

confidence: 99%

Hepatoprotective effects and HSV-1 activity of the hydroethanolic extract ofCecropia glaziovii(embaúba-vermelha) against acyclovir-resistant strain

Petronilho¹,

Costa²,

Kappel³

et al. 2012

Pharmaceutical Biology

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Section: Pharmaceutical Biologymentioning

confidence: 99%

Hepatoprotective effects and HSV-1 activity of the hydroethanolic extract ofCecropia glaziovii(embaúba-vermelha) against acyclovir-resistant strain

Petronilho¹,

Costa²,

Kappel³

et al. 2012

Pharmaceutical Biology

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“…66 The Cecropia glazioui Sneth (Cecropiaceae) plant extract, a popular Latin American folk medicine, was found to reduce stomach acidity by inhibiting gastric proton pumps in animal studies. 67 Such treatments could affect other, co-administered prodrugs which require a low stomach pH for activation.…”

Section: Interactions Affecting Drug Absorptionmentioning

confidence: 99%

The safe usage of herbal medicines: counterindications, cross-reactivity and toxicity

Cock¹

2014

Phcog Commn.

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Background: Plants have been used therapeutically for thousands of years and continue to be the main treatment modality for a large percentage of the world's population. Furthermore, herbal medicine usage is increasing in Western countries as complementary (and sometimes alternative) treatments in conjunction with allopathic medicine. At the same time, the usage of allopathic medicines is being increasingly incorporated into the medicinal systems of developing countries, often resulting in the concurrent usage of both systems. Importance of the Study: Despite the widespread usage in developing countries and the trend of increasing medicinal plant usage in Western countries, herbal medicines remain understudied and there are misunderstandings amongst users and practitioners about the safe usage of these medications, particularly when used in conjunction with other medicines. Herbal medicines are generally not held to the same rigorous standards as allopathic medicines. There is usually a lack of industry regulation and manufacturing standards and guidelines, resulting in inferior (or unsafe) medicines being sold to consumers. Similarly, there is a lack of understanding amongst many medical practitioners of both traditional and allopathic medicine systems of how drugs from the two systems can be safely used together. Aim: The aim of this review is to summarise the current knowledge about herbal medicines and how they can be used safely, with the aim of not only highlighting some of the unsafe uses, but also to stimulate further research. I have also aimed to highlight the need for greater regulation and standardisation of herbal medicines.

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“…A number of spices, herbs and plants methanolic or aqueous extracts possess an antisecrertoy activity. For instance, Cissus quadrangularis , Maytenus ilicifolia, phytosphingosine, Cecropia glaziovii Sneth (Cecropiaceae), alkaloid extract and 2-phenylquinoline obtained from the bark of Galipea longiflora (Rutaceae) and Landolphia owariensis induce significant inhibition of acidity, pepsin content and ulcer index (49)(50)(51)(52)(53)(54), respectively. This potent antisecretory action of spices and plant extracts is likely related to their flavonoid content.…”

Section: Herbs and Gastric Secretionmentioning

confidence: 99%

Spices as Alternative Agents for Gastric Ulcer Prevention and Treatment

Mofleh¹

2011

Peptic Ulcer Disease

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Inhibition of gastric acid secretion by a standardized aqueous extract of Cecropia glaziovii Sneth and underlying mechanism

Cited by 40 publications

References 35 publications

Hepatoprotective effects and HSV-1 activity of the hydroethanolic extract ofCecropia glaziovii(embaúba-vermelha) against acyclovir-resistant strain

Hepatoprotective effects and HSV-1 activity of the hydroethanolic extract ofCecropia glaziovii(embaúba-vermelha) against acyclovir-resistant strain

The safe usage of herbal medicines: counterindications, cross-reactivity and toxicity

Spices as Alternative Agents for Gastric Ulcer Prevention and Treatment

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