Hepatoprotective effects and HSV-1 activity of the hydroethanolic extract ofCecropia glaziovii(embaúba-vermelha) against acyclovir-resistant strain

LC/QTOF profile and preliminary stability studies of an enriched flavonoid fraction of Cecropia pachystachya Trécul leaves with potential antidepressant‐like activity

“…In accordance with our study, Gazal et al () demonstrated that chronic treatment with the aqueous extract of C. pachystachya reversed the increase in TBARS levels in the hippocampus of rats subjected to chronic mild stress, without changing the CAT and SOD activities. Moreover, the hydroethanolic extract of another Cecropia species, C. glaziovii Sneth, inhibited lipid peroxidation on the liver in post‐injury treatment and enhanced the activity of hepatic enzymes (SOD/CAT) (Petronilho et al, ). Thus, our findings suggest that the antidepressant‐like effects of a single dose of EFF‐ Cp on oxidative stress are mediated by the flavonoids, which are known by its antioxidant properties (Grosso et al, ).…”

Antioxidant and Antimicrobial capacity of Cecropia mutisiana Mildbr. (Cecropiaceae) leave extracts

“…The highest IC 50 observed were for high polarity ethanol extract, suggesting presence of phenolic and flavonoid compounds, phytochemically characterized for Cecropia mutisiana including chlorogenic acid, orientin, isoorientin, isovitexin reported by other authors (Nicasio-Torres et al, 2009;Aragão et al, 2010;Petronilho et al, 2012;Cruz et al, 2013). Aragao et al 2010 ORAC methodology allows a more thorough approximation of the antioxidant type, its nature and possible mechanism of action for the species in question.…”

“…Presence of phenols was observed, as well as alkaloid type compounds, saponins, sesquiterpene lactones, lactones, and coumarins. Studies in other species have demonstrated these compounds, mainly chlorogenic acid in Cecropia glaziovii, Cecropia obtusifolia, Cecropia pachystachya, and Cecropia peltata (Andrade-Cetto and Wiedenfeld, 2001;Lacaille et al, 2001;Herrera-Arellano et al, 2004;Andrade-Cetto et al, 2007;Rocha et al, 2007a;Nicasio-Torres et al, 2009;Andrade-Cetto and Vázquez, 2010;Aragão et al, 2010;Arend et al, 2011;Mora Izquierdo et al, 2011;Nicasio-Torres et al, 2011;Petronilho et al, 2012;Beringhs et al, 2013;Cruz et al, 2013). In addition, for Cecropia glaziovii caffeic acid (Arend et al, 2011;Beringhs et al, 2013); protocathechuic acid in Cecropia glaziovii (Lacaille et al, 2001); alkaloids in Cecropia pachystachya, Cecropia glaziovii, and Cecropia peltata (King and Haddock, 1959;Consolini and Migliori, 2005;Ninahuaman et al, 2007).…”

“…Currently no studies have reported antioxidant capacity for Cecropia mutisiana, and are scarce for other species of this same genus (Aragão et al, 2010;Mora Izquierdo et al, 2011;Petronilho et al, 2012). Therefore, for this study a comparison with Rosmarinus officinalis, a plant broadly known for its antioxidant activities was proposed to establish as a biological referral.…”

“…In contrast, antioxidant capacity molecule or molecules for Cecropia mutisiana were different. For other Cecropia species chlorogenic acid (phenol compound) and/or flavonoids such as orientin, isoorientin, and isovetexin were described by Aragao et al (2010), Mora-Izquierdo et al (2011 and Petronilho et al (2012) as the molecules responsible for antioxidant capacity. In this regard, our data evidenced a greater antioxidant capacity through the ABTS methodology compared with DPPH test.…”