2009
DOI: 10.1590/s0100-879x2009000900003
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Inhibition of cyclooxygenase activity by standardized hydroalcoholic extracts of four Asteraceae species from the Argentine Puna

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Cited by 29 publications
(19 citation statements)
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References 15 publications
(15 reference statements)
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“…Similarly, R. urticifolius (green fruit) was up to 20‐fold more active than R. occidentalis 58 but was less active (fivefold) than R. coreanus 59. However, B. chilco was slightly superior to other related species ( B. incarum and B. boliviensis ),60 while L. conferta showed a similar radical‐scavenging activity to L. meyenii 28. In contrast, the activity of C. triplinerve was about 50 times lower than that of C. zeylanicum 22…”
Section: Resultsmentioning
confidence: 94%
“…Similarly, R. urticifolius (green fruit) was up to 20‐fold more active than R. occidentalis 58 but was less active (fivefold) than R. coreanus 59. However, B. chilco was slightly superior to other related species ( B. incarum and B. boliviensis ),60 while L. conferta showed a similar radical‐scavenging activity to L. meyenii 28. In contrast, the activity of C. triplinerve was about 50 times lower than that of C. zeylanicum 22…”
Section: Resultsmentioning
confidence: 94%
“…The assay to obtain the 100 % of LOX and COX activity was performed with DMSO as solvent control. The inhibitory assays were performed in presence of 100 μg/mL of the phenolic-enriched extracts or commercial antiinflammatory compounds: indomethacin (equipotent inhibitory effect on COX-1 and COX-2 [18], nimesulide (specific inhibitor for COX-2) [10,19], caffeic acid (specific inhibitor for LOX) [20] and naproxen (the best NSAIDs on LOX) [21].…”
Section: Inhibition Of Pro-inflammatory Enzymesmentioning
confidence: 99%
“…In a previous paper, we have demonstrated that, Baccharis incarum, Baccharis boliviensis, Chuquiraga atacamensis and Parastrephia lucida that grow in the Argentine Puna (3800 m.o.s.l.) and that are used to reduce oxidative stress and alleviate gout and arthritic pain are able to inhibit cyclooxigenase enzyme (Alberto et al, 2009) as well as Fabiana species shows capacity to inhibit other enzyme of inflammatory pathway. Our results justify the popular use of Fabiana species.…”
Section: Anti-inflammatory Activitymentioning
confidence: 99%