Inhibition of Cortical Laser-Evoked Potentials by Transcutaneous Electrical Nerve Stimulation

Krabbenbos, Imre P.; Brandsma, Dieta; Swol, Christiaan F. P. van; Boezeman, Eduard H.; Tromp, Selma C.; Nijhuis, Harold; Dongen, Eric P.A. van

doi:10.1111/j.1525-1403.2009.00204.x

Cited by 11 publications

(11 citation statements)

References 22 publications

(48 reference statements)

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“…The effect of stimulation at the level of the occipital nerve might change the central pain processing in a similar way as mentioned above. Even after switching of the occipital nerve stimulation device, a prolonged effect can be expected . In our data, ONS causes a delay in the latency of N2P2 resulting in a decreased pain experience, which is in accordance with the preexisting literature .…”

Section: Discussionsupporting

confidence: 92%

Laser-Evoked Potentials in Fibromyalgia: The Influence of Greater Occipital Nerve Stimulation on Cerebral Pain Processing

Plazier

Ost

Snijders

et al. 2015

Neuromodulation: Technology at the Neural Interface

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Section: Discussionsupporting

confidence: 92%

Laser-Evoked Potentials in Fibromyalgia: The Influence of Greater Occipital Nerve Stimulation on Cerebral Pain Processing

Plazier

Ost

Snijders

et al. 2015

Neuromodulation: Technology at the Neural Interface

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“…Natural vibratory and tactile stimulation can delay and decrease LEP . TENS of cutaneous afferents reduced pain perception and N2P2 amplitude . Latency reduction can also occur under distraction and drowsiness .…”

Section: Discussionmentioning

confidence: 99%

Innocuous Peripheral Nerve Stimulation Shifts Stimulus–Response Function of Painful Laser Stimulation in Man

Ristić

Ellrich

2014

Neuromodulation: Technology at the Neural Interface

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“…None of the volunteers were taking medications or reported a (neurological) disease that might affect pain perception. Our research group has experience with the application of laser stimuli and interpreting evoked brain potentials [11]. Verbal informed consent was obtained before entering the study and all participants were free to withdraw at any time.…”

Section: Subjectsmentioning

confidence: 99%

Stimulating Aδ and C-Fibers in the Lower Limb With a 980 nm Diode Laser

Krabbenbos

2013

J Neurol Res

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Background: Laser evoked potentials are increasingly used to investigate the integrity of the nociceptive system. Laser heat stimuli can activate Aδ fibers, activation of C-fibers remains difficult. This study attempts to stimulate Aδ and C fibers separately with a 'grid' to generate respectively late and ultra-late LEPs. A 'grid' is a thin aluminum plate used as a spatial filter to stimulate C-fibers. Furthermore, study subjects pressed a button upon detecting a laser stimulus which was used to measure reaction times (RT) following diode laser stimulation.Methods: Cutaneous heat stimuli were applied at the Th 12 and L 5 dermatome in seventeen volunteers. Conduction velocities (CV) were calculated by measuring latencies of P2 and reaction times (RT). Results: Stimulation condition Th 12no-grid showed a P2 late response at 330 ± 47 ms and L 5 no-grid at 413 ± 53 ms. Mean reaction time during Th 12 no-grid was 537 ± 146 ms, L 5 no-grid 784 ± 334 ms, Th 12 grid 710 ± 195 ms and L 5 grid 1,391 ± 336 ms. During stimulation block Th 12 grid and L 5 grid ultra-late LEPS could not reliably be generated. Median conduction velocities (CV) and their corresponding range were calculated. The median CV RT no grid was 5.8 m/s (range 1.2 -43.3). The median CV LEP no grid was 13.8 m/s (range 4.7 -45.4). The median CV RT grid was 1.9 m/s (range 0.8 -3.7). Ultra-late LEPs could not be generated, although subjects mentioned a long lasting burning pain during Th 12 grid and L 5 grid . Conclusions:This study questions the feasibility of the 'grid' to reliably generate C-fiber responses. Pressing a button upon laser stimulus detection seems preferable for identifying C-fiber stimulation in the lower limb, whereas for Aδ nociceptive pathways laser evoked potentials might be of use.

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Inhibition of Cortical Laser-Evoked Potentials by Transcutaneous Electrical Nerve Stimulation

Cited by 11 publications

References 22 publications

Laser-Evoked Potentials in Fibromyalgia: The Influence of Greater Occipital Nerve Stimulation on Cerebral Pain Processing

Laser-Evoked Potentials in Fibromyalgia: The Influence of Greater Occipital Nerve Stimulation on Cerebral Pain Processing

Innocuous Peripheral Nerve Stimulation Shifts Stimulus–Response Function of Painful Laser Stimulation in Man

Stimulating Aδ and C-Fibers in the Lower Limb With a 980 nm Diode Laser

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