Inhibition by salicylate of porcine lactate dehydrogenase isoenzyme 5

Abstract

45P is the factor. This is simply because the larger the numerical value of the denominator the smaller is the value of the fraction, especially when squared. There is no entirely satisfactory solution to this problem, other than the highly recommended procedure of never using single sets of observations, but it has been found that the mean of experimental and calculated values is a normalizing factor that considerably decreases the bias and provides a fairly satisfactory neutral weighting between large and small experimental variables. The form of each deviation term is thus: 4[(xcalc.-Xexp.)/(XcaIc. + Xexp.)]2 This work was carried out with the aid of a grant from the Science Research Council.