Inherited Diseases and Variations

Radiographic signs of renal disease in rabbits

“…Several kidney diseases have been described in rabbits. Renal agenesis and asymptomatic congenital renal cysts have been recorded (Lindsey and Fox 1994), and lesions associated with bacterial infections such as renal abscesses, staphylococcal nephritis, pyelonephritis and pyelitis have been described in laboratory rabbits by Hinton (1981), who reported that renal fibrosis was more prevalent in older rabbits and postulated that E cuniculi, a microsporidial parasite that is known to cause nephritis in rabbits, might be the cause. Histologically, focal inflammatory lesions may be present at all levels of the renal tubule, usually with minimal involvement of the glomeruli.…”

Biology and Diseases of Rabbits

“…Some cases of hydrocephalus in rabbits have been presumed to be related to a single autosomal recessive gene (hy/hy); however, occurrence with other abnormalities suggests that inheritance may be more complicated (Lindsey and Fox, 1994). Some cases of hydrocephalus in rabbits have been presumed to be related to a single autosomal recessive gene (hy/hy); however, occurrence with other abnormalities suggests that inheritance may be more complicated (Lindsey and Fox, 1994).…”

Studies on the European hare. 45. Dental and cranial anomalies in Austrian and Polish brown hare Lepus europaeus populations

“…In rabbits Oryctolagus cuniculus it occurrs both in wild specimens and in various races reaching a prevalence of up to 10% (Nachtsheim 1936, Geiger 1976). According to Nachtsheim (1936), agenesis of 12 is caised by an (incompletely) dominant gene (Lindsey and Fox 1974). In rabbits agenesis has not been noticed in deciduous I 2 which are changed into permanent peg teeth approximately within the third and fourth week after birth (Nachtsheim 1936).…”

“…As to our knovledge this is the first case of an additional peg tooth reported for Lepus europaeus. It occurs occasionally in rabbits between the two regular permanent I 2 resulting from a single recessive gene (Nachtsheim 1935, Lindsey andFox 1974). Nacltsheim (1936) considered it to be caused by a duplication of the tooth germ of the permanent I 2 (for a general overview of causes of polyodonty in mammals see Volsan 1984).…”

“…However, it is not yet clear to what extent biochemical-genetic diversity is indicative for the endogenic component of variation in morphological characters at the population level (Schnell andSelander 1981, Palmer andStrobeck 1986). Therefore, in addition to biochemical-genetic studies, the geographical analysis of genetically based abnormalities of the dentition and skull bones (Nachtsheim 1936, Torgersen 1951, Griineberg 1965, Lindsey and Fox 1974, Wiesner and Wilier 1974, Meyer 1975, Wolsan 1984 can be of population genetic value (Vigal and Machordom 1987 for Spanish mountain goats). The fact that a reduction or agenesis of the third upper molar obviously occurs more frequently in brown hares from New Zealand than in European populations -a phenomenon probably indicating a genetic bottleneck in hares from New Zealand (Flux 1980) -is a good hint for the utility of surveying morphological anomalies in connection with genetic studies.…”