Ingesta de yodo durante el embarazo: efectos en la función tiroidea materna y neonatal

Rodríguez, Marta Suárez; Azcona, Cristina; Aguilar, Valentín Alzina de

doi:10.1016/j.endonu.2013.01.010

Cited by 5 publications

(2 citation statements)

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“…13,51,54 Tipicamente a hipotiroxinemia não se acompanha por hipotiroidismo, já que a T3 circulante está normal ou aumentada, prevenindo um aumento da TSH acima do limite da normalidade. 55 Contudo, pode desenvolver-se hipotiroidismo, sobretudo nas mulheres predispostas para doença tiroideia e em regiões com défice grave de iodo. 13 A formação de bócio gestacional pode ser explicada por fatores como o défice de iodo, o tabagismo e as gestações sucessivas.…”

Section: Aporte De Iodo E Função Tiroideia Na Gravidezunclassified

Aporte de iodo e função tiroideia na gravidez

Oliveira

Carvalho

Belo

2018

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INTRODUÇÃO O iodo é um micronutriente essencial que, não sendo produzido pelo organismo, deve ser obtido através de fontes exógenas, sobretudo a partir da alimentação. 1-2 Este nutriente é o elemento-chave para a biossíntese de hormonas tiroideias, sendo por isso indispensável para um crescimento e um desenvolvimento normais. 3-9 A produção das hormonas tiroideias requer um aporte adequado de iodo, já que este representa, respetivamente, 59 e 65% dos pesos moleculares das hormonas T3 e T4. 8-11 Por outro lado, o iodo parece exercer ação antioxidante tecidular, diminuindo as lesões causadas pelos radicais livres de oxigénio. 12 As necessidades deste micronutriente variam ao longo da vida, sendo superiores durante a gravidez e a ama

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Section: Aporte De Iodo E Função Tiroideia Na Gravidezunclassified

Aporte de iodo e função tiroideia na gravidez

Oliveira

Carvalho

Belo

2018

RPMGF

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“…Specifically, 3 g/day of iodized salt (one small teaspoon) covers the daily needs of this mineral [16,17]. However, the consumption of iodized salt is not enough to compensate the need for oligoelements in pregnant women, who need to take multivitamins with iodine to obtain adequate ioduria levels [18]. It is also known that the concentration of iodine in cow's milk has increased in recent years, indicating that cow's milk is a relevant source of iodine in our diet [19] that may be of clinical interest during gestation.…”

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confidence: 99%

Reference Values of Thyroid Hormones During the First Trimester of Pregnancy in Valencian Community (Spain) and Their Relationship with Iodine Intake

2020

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Thyroid hormones require special monitoring during the first trimester of gestation. Local reference values should be applied if available, especially in iodine-deficient areas, as generalized iodine supplementation is controversial. The aim of the present study was to establish thyroid stimulating hormone (TSH) and free thyroxine (FT4) reference values in the first trimester of gestation in the Valencian community (Spain) and relate them to iodine intake. A total of 261 healthy pregnant women participated in the study. The calculated reference values were 0.128–4.455 mIU/L for TSH and 0.9–1.592 ng/dL for FT4. The upper TSH reference value for pregnant women in the first trimester in our environment was similar to the latest American Thyroid Association (ATA) recommendation (4 mIU/L). The mean TSH value was significantly lower in smokers, and there were no significant differences when analyzing the influence of iodine supplementation, although the low duration of supplement intake needs to be taken into consideration. Ioduria levels (median 57 µg/L) confirmed iodine deficiency. We found statistically significant differences in ioduria levels among patients who consumed iodized salt and iodine supplements and those who did not. It is essential to focus on recommending adequate consumption of iodized salt and iodine supplements prior to gestation and at least during the first trimester to avoid possible maternal thyroid dysfunction and perinatal complications.

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