Infrared-spectral characteristics of some acetylated, anomeric glycosides

2006

Heteroatom Chemistry

Several N-lactosylated aryl thioureas and benzothiazolyl thioureas have been prepared by the condensation of hepta-O-acetyl-β-D-lactosyl isothiocyanate with aryl amines and 2-aminobenzothiazole/substituted benzothiazoles. Hepta-O-acetyl-β-D-lactosyl isothiocyanate was prepared by the interaction of hepta-O-acetyl-α-D-lactosyl bromide and lead thiocyanate. The structures of these new N-lactosides have been established on the basis of IR, NMR, and mass spectral studies.

Section: Resultsmentioning

confidence: 98%

Synthesis of N‐lactosylated thiourea and benzothiazolyl thiourea

Tale

2006

Heteroatom Chemistry

“…The IR spectrum [11,12] of the product shows characteristics absorption of the lactose unit in the ranges of 900-910 and 1000-1100 cm −1 . The mass spectra [19] of the acetolactose unit show the peak at m/z 619, 331, 229, 169, 127, and 109.…”

Section: Resultsmentioning

confidence: 99%

“…On the basis of elemental analysis and IR [10][11][12][13], NMR [11][12][13][14][15][16], and mass spectral studies [17][18][19] (experimental), the product with mp 125-127 • C was assigned the structure 4-phenyl-5-phenylimino-3-S-(hepta-O-acetyl lactosyl)-1,2,4-thiadiazoline (3a).…”

Section: Resultsmentioning

confidence: 99%

Syntheses and antimicrobial activities of 4‐aryl‐5‐phenylimino‐3‐S‐(hepta‐O‐acetyl lactosyl)‐1,2,4‐thiadiazolines

Mangte

2007

Heteroatom Chemistry

“…The yields of 3, 5 vary within 72 -92%. The structures of 3, 5 were elucidated using IR [26,27], 1 H NMR [26 -28], and mass spectroscopy [29 -30] and elemental analysis.…”

Section: Chemistrymentioning

confidence: 99%

Synthesis, characterization and in vitro antimicrobial evaluation of new glycosyl imidothiocarbamates

Dandale

2011

Pharm Chem J

A series of new glycosyl imidothiocabamates were synthesized and charaterized and their antimicrobial properties were evaluated. These compounds were synthesized by the condensation of per-O-acetyl lactosyl isocyanate with N-aryl-S-benzyl isothiourea and per-O-benzoyl glucosyl aryl isothiourea and characterised using the IR, 1 H NMR, and mass spectroscopy and elemental analysis. The synthesized compounds were screened for their in vitro antimicrobial activity against bacteria (S. aureus, E. coli, P. vulgaris, P. aeruginosa) and fungi (A. niger, Penicillium). Some of these compounds exhibited moderate to good activity, whereas some were inactive.