Infrahepatic caudal/inferior vena cava interruption with azygos/hemiazygos continuation. Vascular anomaly in swine

Jeromel, Miran; Pavčnik, Dušan

doi:10.2478/v10019-010-0029-5

Cited by 5 publications

(4 citation statements)

References 16 publications

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“…In this study, we used adult sheep to test the novel device for following reasons: (1) the size of their heart approximates that of human heart; (2) their coagulation and fibrinolytic systems are closer to that of humans; and (3) they tend to have a stable body size and weight during a long‐term follow‐up when compared with swine . We punctured and created the ASDs at the fossa ovalis areas because we could have a stable ASD size here compared with the septum secundum …”

Section: Discussionmentioning

confidence: 99%

A novel totally biodegradable device for effective atrial septal defect closure: A 2‐year study in sheep

Ouyang

Wang

et al. 2018

J Interven Cardiology

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Section: Discussionmentioning

confidence: 99%

A novel totally biodegradable device for effective atrial septal defect closure: A 2‐year study in sheep

Ouyang

Wang

et al. 2018

J Interven Cardiology

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“…The size of their heart size approximates the size of the human heart and allows large closure devices to be tested. Adult sheep have a stable body size and when compared to swine that continue to grow and put on weight 6,11. They allow for long-term follow-up.…”

Section: Discussionmentioning

confidence: 99%

“…Adult sheep have a stable body size and when compared to swine that continue to grow and put on weight. 6 , 11 They allow for long-term follow-up. In addition, the sheep coagulation and fibrinolytic systems are closer to that of humans compared to those in canine or swine.…”

Section: Discussionmentioning

confidence: 99%

Double BioDisk: a new bioprosthetic device for transcatheter closure of atrial septal defects - a feasibility study in adult sheep

Pavčnik¹,

Tekulve²,

Uchida³

et al. 2012

Radiology and Oncology

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BackgroundTo evaluate the long-term effectiveness and safety of a new Double BioDisk (DBD) device for closure of atrial septal defect (ASD).Materials and methods.ASD was created with transeptal needle (TS) followed by balloon dilatation in 12 sheep weighing 40.1 to 64 kg (mean 55.2 ± 7.1). The ASD diameters were measured after creation and two weeks later before DBD implantation. The DBDs consists of two nitinol rings 18 to 28 mm in diameter connected with small cannulas and covered with a porcine small intestinal submucosa (SIS). They were implanted via a 10 Fr sheath. DBD effectiveness was evaluated by angiocardiography and by intra-cardiac echogram (ICE) with Doppler studies. Two animals were acute, two were followed for 6 weeks, three for 3 months, three for 6 months and two for 12 months.ResultsTS punctures were successful in 10 sheep. In two sheep ASD was created by existing PFO dilation. The ASD size ranged from 13–15 mm (mean 14.1± 0.73 mm) after initial balloon dilation and from 9–13 mm (mean 10.06 ± 1.37 mm) after two weeks. In all animals none of the successfully implanted DBDs spontaneously embolized on release or on follow up. ICE demonstrated no shunting around the DBDs during follows ups. Macroscopic and histologic evaluation of the 6, 12, 24 and 52 weeks animals showed that DBDs were well incorporated in the atrial septum with complete shunt closure. The SIS showed progressive remodeling with the host cells, including endothelization of the DBD devices.ConclusionsASD closure with the Double BioDisk is safe and effective in adult sheep.

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“…The animals underwent standard general anesthesia with intubation and artificial ventilation as described previously. 4,5 Hemostasis was achieved as described previously 6. After exposure of the right femoral artery, a 7 F sheath was introduced to obtain blood for EBC formation.…”

Section: Methodsmentioning

confidence: 99%

Iodine based radiopacity of experimental blood clots for testing of mechanical thrombectomy devices

Luo¹,

Chung²,

Choi³

et al. 2013

Radiology and Oncology

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BackgroundBarium sulfate powder used for radiopacity of experimental blood clots (EBCs) for testing mechanical thrombectomy devices (MTD) has negative effects on EBCs mechanical properties. In vitro and in vivo exploration was performed to determine if the iodine based contrast medium will have less negative effects on the EBCs than barium.Materials and methodsFresh blood from 2 swine was used to create fibrinogen enhanced and thrombin initiated EBC in tubes. Iodine radiopacity was achieved by mixing the blood with 65% Iohexol or by soaking the EBCs for 2 or 24 hours in Iohexol. The EBCs opacified with barium served as controls. In vitro study: The EBCs were subjected to four tests, manual elongation, catheter injection, radiopacity and contrast wash out tests. In vivo study: The common carotid arteries of 2 swine were embolized by either barium EBC or EBC soaked for 24 hours in Iohexol. The duration of radiopacity of the different EBCs was compared.ResultsThe EBCs opacified with Iohexol initially had higher radiopacity than the barium opacified EBCs. However, their opacity rapidly decreased with saline soaking and, particularly, after they were embolized in live animals. The mechanical properties of Iohexol opacified EBCs were inferior to barium opacified EBCs. The Iohexol mixed EBCs were less firm and elastic and half of them fragmented during catheter injection. The Iohexol soaked EBCs exhibited decreased tensile strength and elasticity compared to the barium EBCs.ConclusionsCompared to barium, iodine based contrast medium does not offer any advantage for opacifying EBCs.

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Infrahepatic caudal/inferior vena cava interruption with azygos/hemiazygos continuation. Vascular anomaly in swine

Cited by 5 publications

References 16 publications

A novel totally biodegradable device for effective atrial septal defect closure: A 2‐year study in sheep

A novel totally biodegradable device for effective atrial septal defect closure: A 2‐year study in sheep

Double BioDisk: a new bioprosthetic device for transcatheter closure of atrial septal defects - a feasibility study in adult sheep

Iodine based radiopacity of experimental blood clots for testing of mechanical thrombectomy devices

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