Information-seeking behavior of women in their path to an innovative alternate treatment for symptomatic uterine fibroids

Ankem, Kalyani

doi:10.3163/1536-5050.95.2.164

Cited by 44 publications

(15 citation statements)

References 30 publications

(40 reference statements)

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“…terine leiomyomas are the most common pelvic tumors in the female genital tract and tend to increase in frequency with age, affecting up to 65% of women by the time of menopause (1). Most leiomyomas are asymptomatic, but nearly half of all patients with uterine leiomyomas have clinically important symptoms, with the most frequent symptoms being menorrhagia, pelvic pain, a feeling of pelvic fullness, and infertility (2). For women who do not desire further pregnancies, the established therapy for symptomatic leiomyomas is laparotomy with hysterectomy or myomectomy, which may involve serious morbidity caused by destruction of the completeness of the pelvic floor, interference of blood supply to the ovary, and acceleration of ovarian recession (3,4).…”

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confidence: 99%

Uterine Leiomyomas: Safety and Efficacy of US-guided Suprapubic Transvaginal Radiofrequency Ablation at 1-year Follow-up

Wu¹,

Guo²,

Cao³

et al. 2016

Radiology

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Purpose To assess the safety and efficacy of ultrasonography (US)-guided suprapubic transvaginal (ST) radiofrequency ablation (RFA) in the treatment of symptomatic uterine leiomyomas at 1-year follow-up. Materials and Methods The institutional review board approved this prospective study, and all patients provided informed consent. ST RFA was performed as an outpatient procedure 3 days after menstruation in 51 women (age range, 32-52 years; mean age, 42.2 years) with 62 leiomyomas. The leiomyomas were assessed with conventional and contrast material-enhanced US before and after ST RFA for leiomyoma size, location, and blood flow. All patients were evaluated for postoperative complications, including abdominal pain, injury to surrounding tissues and organs, vaginal bleeding, increased vaginal discharge, fever, dyspnea, and menorrhagia, after ST RFA and at follow-up visits. The leiomyoma volumes, improvement in leiomyoma-related symptoms, effect on quality of life (QOL), and patient satisfaction were assessed and compared before and after ST RFA and at follow-up visits by using statistical analyses. Results Sixty-two leiomyomas were successfully treated with ST RFA until 90% of the leiomyoma was echogenic. At 1-month follow-up, 46 (74%) leiomyomas had no contrast enhancement, five (8%) had peripheral enhancement, eight (13%) had focal enhancement, and three (5%) had scattered enhancement at contrast-enhanced US. At 6-month follow-up, the number of leiomyomas that had no enhancement, peripheral enhancement, focal enhancement, or scattered enhancement was 43 (69%), seven (11%), nine (15%), and three (5%), respectively. The leiomyoma volumes were significantly (P < .05) reduced at 1-, 3-, 6-, and 12-month follow-up (from 33.0 cm(3) ± 25.1 [standard deviation] before treatment to 6.8 cm(3) ± 7.7 at 12-month follow-up). The mean percentage volume reduction at 1-, 3-, 6-, and 12-month follow-up was 28%, 57%, 63%, and 78%, respectively. The scores for symptoms and QOL were all significantly improved (P < .05) at follow-up, going from 45 ± 14 and 65 ± 41, respectively, before treatment to 0 and 100, respectively, at 12-month follow-up. No complications were reported during the periprocedural period or throughout follow-up. Most patients (41 of 45) were satisfied. Conclusion ST RFA may be an effective and safe alternative in the treatment of uterine leiomyomas. (©) RSNA, 2015 Online supplemental material is available for this article.

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confidence: 99%

Uterine Leiomyomas: Safety and Efficacy of US-guided Suprapubic Transvaginal Radiofrequency Ablation at 1-year Follow-up

Wu¹,

Guo²,

Cao³

et al. 2016

Radiology

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“…These variables include gender, age, ethnicity or race, socioeconomic status, psychosocial variables, literacy skills, health literacy, information-seeking behaviors, learning styles, and others. 4,5,12,[26][27][28][29][30][31][32] In order to navigate the health care system and make complicated health decisions, patients and health consumers also need basic literacy and health literacy skills. They must be able to find, understand, and make active use of relevant information, and these activities involve higher level cognitive skills.…”

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confidence: 99%

Development and Evaluation of a Cancer Information Web Portal: The Impact of Design and Presentation on User Engagement

Schilling

McDaniel

2010

Journal of Consumer Health On the Internet

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Although cancer is one of the most prevalent chronic illnesses in the United States, many consumers do not have access to reliable, state-of-the-art cancer information on the Web. The Cancer Information portal translates evidence-based disease prevention and management information for text-based and multimedia delivery for diverse and low literacy citizens. Open-ended ''key informant'' interviews with consumers provided feedback on content presentation, and the portal's look, feel, and navigation. Evaluation assessed the portal's (1) readability, (2) required expertise, (3) user satisfaction, and (4) user comfort. Recommendations include improvements in key design areas to increase user efficacy and strengthen the portal's identity.

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“…It mostly occurs in women between of 35 and 50 years of age and the estimated prevalence in the United States is 20-40% (2). The most frequent clinical symptoms are menorrhagia, lower abdominal pain, a sensation of pelvic fullness and infertility (3,4). Available treatments are medication, surgery (including hysterectomy and myomectomy) and less invasive therapies.…”

Section: Introductionmentioning

confidence: 99%

Contrast‑enhanced ultrasound is better than magnetic resonance imaging in evaluating the short‑term results of microwave ablation treatment of uterine fibroids

Zhang

Fan

et al. 2017

Exp Ther Med

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Abstract. Contrast-enhanced ultrasound (CEUS) and magnetic resonance imaging (MRI) were compared in evaluating the short-term effects of microwave ablation (MWA) on uterine fibroids. A total of 60 patients with uterine fibroids treated by MWA were enrolled in the experimental group during their two-year follow-up period according to the inclusion criteria. Conventional two-dimensional US, MRI and CEUS were performed to determine the volume reduction and the fibroid residue by displaying the size, echo and signal intensity of fibroids prior to and after MWA treatment. As the control group, 60 consecutive patients were recruited on their follow-up visit at least two years after MWA treatment of uterine fibroids. Significant differences were observed in the wash-in rate (WiR) of the fibroid tissue, start time difference, rise time ratio (RTR) and WiR ratio between the experimental and control groups (P<0.05). However, the WiR of fibroid vessel, total area under the curve of fibroid vessel and tissue, and rise time difference (RTD) between fibroid vessel and tissue did not display any significant differences between the two groups. Fibroids were either reduced in volume or cured by MWA therapy in patients with uterine fibroids. The reductions in volume of hypointense, isointense and hyperintense fibroids were 62.42±18.13, 53.27±10.05 and 47.43±9.56%, respectively, on T1-weighted imaging (T1WI). On T2WI, the corresponding reductions were 67.32±32.63, 59.36±19.36 and 42.63±10.37%, respectively. The higher the signal intensity on T1WI and T2WI, the lower the reduction in volume. It is indicative that different blood supply to fibroids results in different ablation. CEUS was proved to be more effective than MRI in evaluating the effects of MWA on uterine fibroids during the first postoperative year.

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Information-seeking behavior of women in their path to an innovative alternate treatment for symptomatic uterine fibroids

Abstract: Health sciences librarians may inform women about their health and treatment options by guiding women to easily readable, authoritative, and reliable information sources, including Web information sites.

Cited by 44 publications

References 30 publications

Uterine Leiomyomas: Safety and Efficacy of US-guided Suprapubic Transvaginal Radiofrequency Ablation at 1-year Follow-up

Uterine Leiomyomas: Safety and Efficacy of US-guided Suprapubic Transvaginal Radiofrequency Ablation at 1-year Follow-up

Development and Evaluation of a Cancer Information Web Portal: The Impact of Design and Presentation on User Engagement

Contrast‑enhanced ultrasound is better than magnetic resonance imaging in evaluating the short‑term results of microwave ablation treatment of uterine fibroids

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