Influenza Vaccination and Vitamin K Antagonist Treatment

Abstract

clinicaltrials.gov Identifier: NCT00222638.

The effect of COVID-19 vaccination on anticoagulation stability in adolescents and young adults using vitamin K antagonists

“…The increase of INRs out of range was not associated with an increase in complications after COVID-19 vaccination. The limited number of complications after COVID-19 vaccination is in line with the literature on post-vaccination complications in both adult and paediatric VKA users [ [30] , [31] , [32] , [33] , [34] , [35] , [36] ]. However, Dutch anticoagulation clinics were encouraged to monitor the anticoagulation status shortly after COVID-19 vaccination, so any necessary dose adjustments could rapidly be made.…”

“…Stability of anticoagulation after vaccination has mainly been described in the adult and elderly VKA users. In most studies, no effect on the INR after vaccination was observed [ [30] , [31] , [32] , [33] , [34] ]. Only two studies have looked at the percentage of INRs out of range after COVID-19 vaccination [ 6 , 35 ].…”