Influences of niobium pentoxide on roughness, hydrophilicity, surface energy and protein absorption, and cellular responses to PEEK based composites for orthopedic applications

Abstract

PNCs prepared by pressing–sintering exhibited improved surface properties and excellent cellular responses.

Progress in Niobium Oxide-Containing Coatings for Biomedical Applications: A Critical Review

“…The highest rate of the in vivo osseointegration of tested implants is also registered for Nb. 86 , 87 To fabricate bulk synthetic implants, it is encouraged to alloy the Nb with other biocompatible materials, such as Ti, rather than using it in its pure form. When alloyed with Ti, Nb can stabilize the β phase, which contributes to decreasing the elastic modulus of Ti, thereby diminishing the risk of the “stress shielding”.…”

“…It is tightly adherent to the Nb and can fully cover its surface. 86 , 95 − 99 Nb 2 O 5 illustrates high resistance against both corrosion and wear, excellent thermodynamic, thermal, and chemical stabilities, high reflective index, low density, outstanding mechanical strength, and fracture toughness, nontoxicity, hypoallergenic, great biological characteristics, enabling cellular attachment, growth, spreading, proliferation, metabolic activity, collagen synthesis, seriously influencing endothelial cell responses, alkaline phosphatase activity (ALP), and supporting HAp formation in the various physiological media due to the small lattice mismatch (1.1%) between the oxide and mineral HAp phase. 73 , 100 − 110 Due to the above properties, Nb 2 O 5 coatings show significant potential for applications in a variety of industrial applications, such as electrochromic devices, optical windows, solar cells, sensing devices, catalysts, supercapacitors, and biomedical.…”

Nb2O5‐Based Photocatalysts

“…[ 71 ] Besides, the NbCl 5 and Nb‐fluoro complex were used in the synthesis of H‐Nb 2 O 5 and TT‐Nb 2 O 5 particles, respectively. [ 72 ] In the hydrolysis process, structure‐directing agents were introduced, such as the lauryl amine hydrochloride and F127. [ 73 ] The smaller particles of Nb 2 O 5 were observed with the increase of pH.…”

Bioinspired Modifications of PEEK Implants for Bone Tissue Engineering

“…Other coating materials such as tantalum, tantalum pentoxide, and niobium pentoxide can not only elevate the surface energy, surface roughness, hydrophilicity, protein absorption, and mechanical properties of PEEK implants, they can also induce positive cellular responses and osteointegration (Lu et al, 2015;Mei et al, 2019;Ge et al, 2020). Silicon-based compounds Reproduced with permission from Dong et al (2020).…”