Influence of Visceral Obesity for Postoperative Pulmonary Complications After Pancreaticoduodenectomy

Abstract

Visceral obesity was the independent risk factor for the incidence of PPCs after pancreaticoduodenectomy. Preoperative VFA measurement using CT scan is a useful tool for the prediction of the development of PPCs compared to BMI calculation.

Computed tomographic measurements predict component separation in ventral hernia repair

“…Although we have not yet applied these cutoff points to an external data set for validation, we plan to do that in the near future to verify the conclusions. Our findings in this ventral hernia study population are in line with prior findings published in the colorectal and urology literature, which found that wound and total complications are increased with increasing AWT [5,7,8]. Patients with large ventral hernias (classified as hernia area >100 cm 2 ) are at increased risk of seroma formation and worse long-term quality of life outcomes according to recently published data [12].…”

Randomized clinical trial of isolated Roux-en-Y versus conventional reconstruction after pancreaticoduodenectomy

“…In addition, four of the five patients with a grade C pancreatic fistula were men. Although body mass index was not associated with pancreatic fistula in a previous report 37 , fatty pancreas has been proposed as a risk factor for pancreatic fistula 38 -41 , and there are sex differences in fat infiltration of the pancreas. Future studies will have to take all these factors into account.…”

Low skeletal muscle radiation attenuation and visceral adiposity are associated with overall survival and surgical site infections in patients with pancreatic cancer

“…Although a low skeletal muscle area has been associated with poor outcome in various cancer types, including pancreatic cancer, the amount of (visceral) adipose tissue seems to have more impact on outcome in patients with pancreatic cancer. Several studies found a strong association between increased VAT and post‐operative pancreatic fistula in patients with pancreatic cancer, while other studies found associations with increased major post‐operative complications and pulmonary complications . Increased fat content in muscle tissue (myosteatosis) also seems to impact clinical outcome in pancreatic cancer.…”

“…Several studies found a strong association between increased VAT and post-operative pancreatic fistula in patients with pancreatic cancer, 8,10,11 while other studies found associations with increased major post-operative complications 12 and pulmonary complications. 13 Increased fat content in muscle tissue (myosteatosis) also seems to impact clinical outcome in pancreatic cancer. In fact, there are indications that increased muscle fat content rather than low muscle mass is associated with shorter survival in patients with unresectable pancreatic cancer.…”