Randomized clinical trial of isolated Roux-en-Y versus conventional reconstruction after pancreaticoduodenectomy

Abstract

NCT00915863 (http://www.clinicaltrials.gov/) and UMIN000001967 (http://www.umin.ac.jp/).

Isolated Roux‐en‐Y pancreaticojejunostomy versus conventional pancreaticojejunostomy after pancreaticoduodenectomy: a systematic review and meta‐analysis

“…The search strategy generated 217 relevant clinical studies, among which eight full text articles were identified for further investigation. Of these, two studies were excluded: one study only compared isolated Roux reconstruction with pancreaticogastrostomy, while the other study included general Roux reconstruction in the analysis.…”

“…Of these, two studies were excluded: one study only compared isolated Roux reconstruction with pancreaticogastrostomy, while the other study included general Roux reconstruction in the analysis. Finally, six studies were included, of which two were prospective randomized comparative studies , one prospective nonrandomized study and three retrospective comparative studies . The study selection process is shown in Figure .…”

“…The anastomotic techniques and definitions of POPF used are shown in Table . Four studies included patients undergoing both PD and pylorus‐preserving pancreaticoduodenectomies, while the other two included patients undergoing only PD. Because of variations in the definitions of POPF, included studies were analyzed separately to determine potential different treatment effects in the groups created for the present study.…”

Delayed gastric emptying following pancreatoduodenectomy with alimentary reconstruction according to Roux-en-Y or Billroth-II

“…A limitation of this study was the different understanding of the surgical reconstruction methods. Two studies compared conventional single loop reconstruction with ReY reconstruction [29, 31], while only one study intentionally compared ReY and BII, again favoring BII reconstruction [19]. However, differences regarding the local setting (e.g.…”

Total bilirubin amount in drainage fluid can be an early predictor for severe biliary fistula after hepatobiliary surgery

“…Despite the advances in the surgical and postoperative management techniques, the risk of development of biliary fistula remains a problem after complex hepatobiliary surgery (1)(2)(3)(4)(5). An undrained biliary fistula may be further complicated by abdominal abscess formation and sepsis, necessitating long-term drainage or even surgical intervention (6).…”