Influence of the spray adjuvant on the toxicity effects of a glyphosate formulation

Coalova, Isis; Molina, Marı́a del Carmen; Chaufan, Gabriela

doi:10.1016/j.tiv.2014.06.014

Cited by 44 publications

(26 citation statements)

References 44 publications

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“…The most important thing is the unexpected side effects on non-target species of glyphosate formulations; the toxic effects of glyphosate formulations were evident in hepatic (HepG2), embryonic (HEK293), and placental (JEG3) cell lines, 18) and cell apoptosis induced by glyphosate formulations in HepG2 cells has been demonstrated. 15) It is very important to exploit a new glyphosate adjuvant. It is fortunate that we have developed a new adjuvant A-178 ® based on coconut shell extracts.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have shown that adjuvants by themselves or in commercial formulations play a role in the toxicity attributed to herbicides. 15,32,33) Developing new adjuvants to decrease the toxicity of glyphosate-based herbicides is critical.…”

Section: Discussionmentioning

confidence: 99%

“…An adjuvant is a reagent that can increase the efficacy of other reagents. 15) In the particular case of agrochemicals, an adjuvant is usually broadly defined as any substance separately added to a pesticide product that will increase the performance of the pes-ticide product. People often use an adjuvant that is a non-herbicidal additive to enhance the effect of the herbicide.…”

Section: Introductionmentioning

confidence: 99%

“…Adjuvants can be divided into two general types based on use states: formulation adjuvants and spray adjuvants. The first type of adjuvant is the part of the formulation; the second type is mixed with the pesticide in the spray tank 15) before application on the field. The most common type of spray adjuvant is a surfactant that can reduce the surface tension of a spray droplet and the waxy surface of a leaf that causes more leaf surface area to be covered with droplets.…”

Section: Introductionmentioning

confidence: 99%

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A natural adjuvant shows the ability to improve the effectiveness of glyphosate application

Hao

Zhang

et al. 2019

J. Pestic. Sci.

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Glyphosate is a common herbicide used worldwide, but its adjuvant has not been studied much. A new adjuvant A-178 ® , based on the coconut shell extracts, has been developed for glyphosate (glyphosate isopropylamine salt: GP). The potency of the new adjuvant was compared with traditional adjuvant polyethoxylated tallow amine (POEA). Field study has shown that A-178 ® can improve the herbicidal effect of GP formulation, and, as compared with 41% GP mixed with 7% POEA (GPP), 41% GP mixed with 7% A-178 ® (recommended dose, GPA) is more effective for weed control. GPA improved herbicidal activity against GP alone by 79.27% and against GPP by 27.38% at 500 g a.i./ha. A-178 ® decreased the surface tension, increased the spreading area of GP, and improved the uptake of GP in cockspur (Echinochloa crus-galli L.). Our results indicated that the new adjuvant shows better ability to improve glyphosate efficacy than does POEA.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A natural adjuvant shows the ability to improve the effectiveness of glyphosate application

Hao

Zhang

et al. 2019

J. Pestic. Sci.

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“…In vitro bioassays are thus particularly well suited for large-scale screening of countless contaminant and mixture scenarios (Escher and Leusch, 2012;Ilboudo et al, 2014). Despite these strengths and obvious capacity for exploring the effect of chemical mixtures, there are few studies applying in vitro bioassays to characterise pesticide-additives interactions (e.g., Coalova et al, 2014;Fine et al, 2016;Zahn et al, 2018). The objective of this study was to compare the toxicity of laboratory-grade active ingredients and additives commonly found in household pesticides to the toxicity of the commercially available products, using two well established in vitro bioassaysinhibition of luminescence in bacteria (cytotoxicity) and inhibition of photosynthesis and non-specific toxicity in green microalgae.…”

Section: Introductionmentioning

confidence: 99%

In vitro bioassays reveal that additives are significant contributors to the toxicity of commercial household pesticides

et al. 2018

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Pesticides commonly used around households can contain additives of unknown concentrations and toxicity. Given the likelihood of these chemicals washing into urban waterways, it is important to understand the effects that these additives may have on aquatic organisms. The aim of this study was to compare the toxicity of commercially available household pesticides to that of the active ingredient(s) alone. The toxicity of five household pesticides (three herbicides and two insecticides) was investigated using a bacterial cytotoxicity bioassay and an algal photosynthesis bioassay. The commercial products were up to an order of magnitude more toxic than the active ingredient(s) alone. In addition, two commercial products with the same listed active ingredients in the same ratio had a 600× difference in potency. These results clearly demonstrate that additives in commercial formulations are significant contributors to the toxicity of household pesticides. The toxicity of pesticides in aquatic systems is therefore likely underestimated by conventional chemical monitoring and risk assessment when only the active ingredients are considered. Regulators and customers should require more clarity from pesticide manufacturers about the nature and concentrations of not only the active ingredients, but also additives used in commercial formulations. In addition, monitoring programmes and chemical risk assessments schemes should develop a structured approach to assessing the toxic effects of commercial formulations, including additives, rather than simply those of the listed active ingredients.

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Monsanto's Roundup verdicts portend liability for some pesticide health damages

Centner

2020

Agronomy Journal

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Three California juries have found that Monsanto should be liable for millions of dollars in non-economic losses to pesticide users and punitive damages, although the verdicts are on appeal. The plaintiffs in the lawsuits claimed Monsanto was negligent in failing to provide training on how to use Roundup and for not providing adequate warnings about the product's dangers. The punitive damage awards resulted from jurors finding that the defendant had engaged in malice, oppression, or fraud. In June 2020, Monsanto's owner Bayer reached an agreement to resolve approximately 125,000 Roundup product liability claims for US$10.1 billion. The verdicts and the proffered settlement suggest that pesticide products that unduly impair human health are not acceptable under American liability principles. Manufacturers need to design products that are reasonably safe and convey sufficient warning information to minimize damages to users and property. The placement of damage costs on product manufacturers is intended to encourage the development of safer pesticide products and the development of alternative non-chemical pest-control measures.

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Influence of the spray adjuvant on the toxicity effects of a glyphosate formulation

Cited by 44 publications

References 44 publications

A natural adjuvant shows the ability to improve the effectiveness of glyphosate application

A natural adjuvant shows the ability to improve the effectiveness of glyphosate application

In vitro bioassays reveal that additives are significant contributors to the toxicity of commercial household pesticides

Monsanto's Roundup verdicts portend liability for some pesticide health damages

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