Influence of the solvent system on the composition of phenolic substances and antioxidant capacity of extracts of grape (<i>V</i><i>itis vinifera</i> L.) marc

Agustin-Salazar, Sarai; Medina-Juárez, Luis Ángel; Soto‐Valdez, Herlinda; Manzanares‐López, F.; Gámez-Meza, Nohemí

doi:10.1111/ajgw.12063

Cited by 31 publications

(20 citation statements)

References 24 publications

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“…Although maceration and water infusion are conventional extraction processes, they are still used today [35,36]. These methodologies have adopted the use of solvents such as ethanol, methanol, acetone and not just water for the extraction of bioactive compounds [14,37,38]. These conventional extraction methods are characterized by the use of large amounts of solvent, lower extraction yields, and long extraction times compared to other methods.…”

Section: Conventional Methodsmentioning

confidence: 99%

Conventional and Emerging Extraction Processes of Flavonoids

et al. 2020

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Flavonoids are a group of plant constituents called phenolic compounds and correspond to the nonenergy part of the human diet. Flavonoids are found in vegetables, seeds, fruits, and beverages such as wine and beer. Over 7000 flavonoids have been identified and they have been considered substances with a beneficial action on human health, particularly of multiple positive effects because of their antioxidant and free radical scavenging action. Although several studies indicate that some flavonoids have provident actions, they occur only at high doses, confirming in most investigations the existence of anti-inflammatory effects, antiviral or anti-allergic, and their protective role against cardiovascular disease, cancer, and various pathologies. Flavonoids are generally removed by chemical methods using solvents and traditional processes, which besides being expensive, involve long periods of time and affect the bioactivity of such compounds. Recently, efforts to develop biotechnological strategies to reduce or eliminate the use of toxic solvents have been reported, reducing processing time and maintaining the bioactivity of the compounds. In this paper, we review, analyze, and discuss methodologies for biotechnological recovery/extraction of flavonoids from agro-industrial residues, describing the advances and challenges in the topic.

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Section: Conventional Methodsmentioning

confidence: 99%

Conventional and Emerging Extraction Processes of Flavonoids

et al. 2020

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“…Thus, the comparison of the suitability of the distinct methods assayed so far shows that hydroalcoholic solutions provides quite high yield of total extracts, although they are not highly selective for the distinct classes of phenolics present in the residues [ 52 , 175 , 176 , 177 ]. Another solvent widely employed in the extraction of winery waste phenolics is methanol (MeOH), which obtains high concentrations of these target analytes.…”

Section: Current Extractive Techniques For Bioactive Phytochemicalmentioning

confidence: 99%

“…In this regard, ethanol (EtOH) has been studied as a more environmentally friendly solvent, recognized as safe according to the European Food Safety Authority (EFSA) and FAO/WHO Expert Committee on Food Additives [ 178 , 179 ]. Concerning the comparison between distinct solvents, recently, the effect of solvent systems (MeOH and EtOH) on the efficiency of the extraction of total phenolic compounds, total flavonoids, and individual phenolics, as well as on the antioxidant capacity of the extracts obtained from grape pomace, and its constituents (peduncle, skin and seed) has been further investigated [ 175 ]. This analysis described the close relation between the solvent used and the specific residue considered in order to get the highest yield of different compounds.…”

Section: Current Extractive Techniques For Bioactive Phytochemicalmentioning

confidence: 99%

Natural Bioactive Compounds from Winery By-Products as Health Promoters: A Review

Teixeira

Baenas

Domínguez‐Perles

et al. 2014

IJMS

463

364

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The relevance of food composition for human health has increased consumers’ interest in the consumption of fruits and vegetables, as well as foods enriched in bioactive compounds and nutraceuticals. This fact has led to a growing attention of suppliers on reuse of agro-industrial wastes rich in healthy plant ingredients. On this matter, grape has been pointed out as a rich source of bioactive compounds. Currently, up to 210 million tons of grapes (Vitis vinifera L.) are produced annually, being the 15% of the produced grapes addressed to the wine-making industry. This socio-economic activity generates a large amount of solid waste (up to 30%, w/w of the material used). Winery wastes include biodegradable solids namely stems, skins, and seeds. Bioactive compounds from winery by-products have disclosed interesting health promoting activities both in vitro and in vivo. This is a comprehensive review on the phytochemicals present in winery by-products, extraction techniques, industrial uses, and biological activities demonstrated by their bioactive compounds concerning potential for human health.

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“…The concentration of primary phenolic compounds in GSE, gallic acid, catechin, and epicatechin was determined by high‐performance liquid chromatography (HPLC, LC‐20 AD Schimadzu, Japan) . Chromatographic separation was carried out with an RP‐18 column (150 mm × 3 mm, 5 μm, Phenomenex, Gemini 5u C18, USA) by isocratic elution.…”

Section: Methodsmentioning

confidence: 99%

Characterization of cyclic olefin copolymer‐coated chitosan bilayer films containing nanocellulose and grape seed extract

Söğüt

Seydim

2018

Packag Technol Sci

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This study evaluated the effect of applying cyclic olefin copolymer (COC) on the physico‐mechanical properties of chitosan (CH) film. Grape seed extract (GSE) (15%, w/w) was added to the CH film solutions to develop an active bilayer, while also adding nanocellulose (NC) (0% to 2%, w/w) to obtain better mechanical properties for CH. Characterization was carried out by contact angle measurements, scanning electron microscopy (SEM), optical analysis, and tensile and water permeability tests. SEM images showed that there was a functional adhesion layer between the CH and the COC, while a detachment occurred for bilayer films with GSE. The formation of a COC layer on the CH surface with the addition of NC improved the water vapor permeability, while the addition of GSE had an adverse effect on the water vapor permeability. The addition of NC into the CH films reduced their water uptake and solubility. The CH film surface showed lower contact angle values, whereas higher contact angle values were observed for CH film surfaces with GSE and NC. The inclusion of NC resulted in an increased elastic modulus and a decrease in TS and ε (%) values. All film samples showed antimicrobial activity against Escherichia coli and Listeria monocytogenes. Moreover, film samples with added GSE showed antioxidant properties with 2,2‐Diphenyl‐1‐picrylhydrazyl scavenging activity ranging from 14.33 ± 0.24 to 20.45 ± 0.07%. The bilayer films will have a potential use in transferring functional compounds as an active packaging material layer along with conventional polymers.

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Influence of the solvent system on the composition of phenolic substances and antioxidant capacity of extracts of grape (Vitis vinifera L.) marc

Cited by 31 publications

References 24 publications

Conventional and Emerging Extraction Processes of Flavonoids

Conventional and Emerging Extraction Processes of Flavonoids

Natural Bioactive Compounds from Winery By-Products as Health Promoters: A Review

Characterization of cyclic olefin copolymer‐coated chitosan bilayer films containing nanocellulose and grape seed extract

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