Influence of the Season on the Metabolic Profile in Chios Sheep

Dzadzovski, Igor; Celeska, Irena; Ulchar, Igor; Janevsкi, Aleksandar; Kirovski, Danijela

doi:10.14432/j.macvetrev.2015.06.048

Cited by 7 publications

(5 citation statements)

References 28 publications

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“…In this research, serum BHBA values at 4 months' pregnancy were higher than at other periods in both breeds ( Table 2). BHBA is an indirect indicator of negative energy balance and the difference in BHBA concentrations between pregnant and non-pregnant ewes may be due to the decreased alimentary energy resources in pregnant sheep (DZADZOVSKI et al, 2015). Circulating BHBA in Chios were significantly lower than in Mehraban ewes at all studied time periods (Table 2; P<0.05).…”

Section: Discussionmentioning

confidence: 93%

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Comparison of circulating metabolic and hepatic indices between fat-tailed and semi-fat-tailed ewes in different pre and post-partum periods

Chalmeh¹,

Pourjafar²,

Badiei³

et al. 2019

Vet. arhiv

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SEBdAni: Comparison of circulating metabolic and hepatic indices between fattailed and semi-fat-tailed ewes in different pre and post-partum periods. Vet. arhiv 89, 43-53, 2019. ABSTrACT Tail fat is present in some breeds of sheep and they use this fat according to their energy requirements. We hypothesized that this fat deposition may interfere with the metabolism of ewes during pregnancy and lactogenesis. Hence, the present study was carried out to clarify the probable effect of tail fat on metabolic and hepatic biomarkers during different pre-and post-partum periods of fat-tailed in comparison with semifat-tailed ewes. Adult Mehraban (n = 10) and Chios (n = 10) ewes were selected and blood sampling was performed from all ewes at 2 and 4 months after mating, and 1, 2 and 3 months after parturition. Serum concentrations of glucose, total protein, albumin, globulin, aspartate aminotransferase, alanine transaminase, gamma glutamyl transferase, beta-hydroxy acid, non-esterified fatty acids, triglyceride, cholesterol, high, low and very low density lipoproteins, total, direct and indirect bilirubin were assayed in all specimens. Glucose in Chios ewes was significantly higher than in Mehraban at all the times studied. The circulating levels of aspartate aminotransferase, alanine transaminase, gamma glutamyl transferase, triglyceride, cholesterol, high, low and very low density lipoproteins, beta-hydroxy acid and non-esterified fatty acids were significantly higher in Mehraban ewes than in the Chios breed at different pre-and post parturient periods. The results of the current research revealed that metabolic and hepatic biomarkers alter during the pregnancy and lactation periods in sheep, which reflects the energy demands and metabolic alterations during these periods. Furthermore, it may be stated that the presence of tail fat in Mehraban ewes may alter the metabolic and hepatic functions in this breed. Tail fat may interfere with lipid metabolism and hepatic function during peri-parturient periods and it may be suggested that semi-fat-tailed breeds, such as Chios, may have more intensive metabolic pathways due to lower body fat storages.

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Section: Discussionmentioning

confidence: 93%

“…Other indicators of liver dysfunction are serum proteins levels, especially albumin, which decrease during hepatic insufficiency (DZADZOVSKI et al, 2015). Particularly, the serum protein fraction pattern could provide information about dehydration, plasma volume expansion and hepatic function (PICCIONE et al, 2012).…”

Section: Discussionmentioning

confidence: 99%

Comparison of circulating metabolic and hepatic indices between fat-tailed and semi-fat-tailed ewes in different pre and post-partum periods

Chalmeh¹,

Pourjafar²,

Badiei³

et al. 2019

Vet. arhiv

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“…Alkaline phosphatase (ALP) is an intrahepatic enzyme found mainly in the biliary ducts and placenta (Al-Hadithy, Badawi and Mahmood 2013) and its serum concentrations are considered valuable parameters for the diagnosis of ketosis in sheep (Sargison et al 1994). In an assay with Chios sheep that manifested clinical signs of pregnancy toxaemia, the ALP concentration reached 196.55 U/L (Dzadzovski et al 2015). Studying white-faced Western-breed ewes at late gestation, Zywicki et al (2018) reported a minimum serum ALP concentration of 36 U/L, whereas Yokus et al (2006) observed an average value of 59 U/L in Sakiz-Awassi crossbreed sheep during early pregnancy.…”

Section: Discussionmentioning

confidence: 99%

Serum biochemical reference ranges for pregnant sheep

et al. 2021

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Late pregnancy is accompanied by dramatic changes in the metabolism of sheep, in which the nutrient requirements increase and the metabolic capacity of ewes is under severe stress due to the rapid foetal growth and development of the mammary gland. The blood metabolic profile can be used to monitor these alterations, which can lead to metabolic disorders such as pregnancy toxaemia. However, data available on serum parameters in sheep do not consider physiological state. Therefore, the present study aimed to determine the biochemical reference ranges for pregnant ewes, including serum energy, protein and enzyme-related metabolites. Data from a variety of metabolites were obtained from experiments performed in several institutions and commercial farms using Santa Inês, Dorper, Lacaune, Morada Nova, Bergamacia and Suffolk ewes reared under different conditions (grazing, feedlot, semi-feedlot, collective and/or individual pens, and metabolic cages) from 2006 to 2017. All animals were healthy and without feed restriction. Data from ewes with any clinical manifestations were removed. The metabolic energy profile included data of glucose, cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein and very-low-density lipoprotein levels; the metabolic protein profile included the metabolites total protein, uric acid, urea, albumin, and creatinine; and the metabolic enzymatic profile included the enzymes aspartate aminotransferase, gamma-glutamyl transferase and alkaline phosphatase. The reference ranges were estimated using the software RefVal 4.11. Dixon’s test was used to identify and remove outliers. The confidence intervals and percentiles were estimated using the nonparametric method of bootstrap when data were not normally distributed. A 95% confidence level was used. The serum biochemical reference ranges for pregnant sheep determined in our study were strongly divergent from those established by one of the most cited books on the topic, especially considering the high serum urea and cholesterol concentrations and low levels of blood glucose observed. Therefore, it is essential to consider physiological status when evaluating the blood metabolic profile of pregnant ewes in order to maintain an adequate nutritional management and to prevent health disorders that may lead to productive and reproductive losses.

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“…Pregnant sheep exposed to low environmental temperatures have increased energy demands due to the undesirable environmental conditions [35], and moreover, they have reduced feed intake [35], which can further contribute to development of the disorder. Low environmental temperatures can also result in hypoglycaemia, which is a prime feature of pregnancy toxaemia [36]. Potentially, the increased wind speed and the low temperatures can also have indirect effects; for example, they can impede easy access of farmers to their animals, reducing the care provided to them, or they can result in freezing of water within pipes, thus stopping the availability of water to the animals, which in turn would lead to reduced feed intake, precipitating a metabolic imbalance and finally the development of the disorder [37].…”

Section: Potential Associations Of Climatic Changes With Small Ruminant Healthmentioning

confidence: 99%

Long-Term Climatic Changes in Small Ruminant Farms in Greece and Potential Associations with Animal Health

et al. 2022

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The objectives of this work were (a) to present the changes in climatic parameters from 1989 to 2019, in 444 locations throughout Greece, where small ruminant farms have been based and (b) to present associations of the changes in the climatic parameters with clinical data related to small ruminant health. Climatic variables (1989–2019) were obtained for 444 locations with small ruminant farms throughout Greece. During this period, significant increases were noted in temperature-related parameters (annually 0.05 °C for average temperature and 0.14 °C for temperature range) and precipitation (annually 0.03 mm). There were significant differences in climatic conditions between locations of farms in accord with the management system applied therein, as well as in accord with the breed of animals on the farms (e.g., higher average temperature in locations with Greek breeds, higher temperature range in locations with imported breeds). There were significant associations of temperature-related parameters with the annual frequency of cases of neonatal hypothermia seen at a veterinary teaching hospital, as well as with the average proportion of Haemonchus contortus larvae in faecal samples and the frequency of cases of H. contortus resistance reported by a veterinary parasitology laboratory.

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Influence of the Season on the Metabolic Profile in Chios Sheep

Cited by 7 publications

References 28 publications

Comparison of circulating metabolic and hepatic indices between fat-tailed and semi-fat-tailed ewes in different pre and post-partum periods

Comparison of circulating metabolic and hepatic indices between fat-tailed and semi-fat-tailed ewes in different pre and post-partum periods

Serum biochemical reference ranges for pregnant sheep

Long-Term Climatic Changes in Small Ruminant Farms in Greece and Potential Associations with Animal Health

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