2015
DOI: 10.5433/1679-0359.2015v36n4p2679
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Abstract: The measurement of serum parameters during general anesthesia procedures are subject to variations due to differences in protocol, splenic storage, and by the instituted fluid therapy. The aim of this study was to assess the hematocrit changes promoted by controlled fluid therapy and general anesthesia. Six mongrel female dogs underwent an anesthetic protocol with acepromazine (0.03 mg kg -1 ) and tramadol (5 mg kg -1 ) for premedication, induction with propofol (3 mg kg -1 ), and maintained with isoflurane an… Show more

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Cited by 2 publications
(4 citation statements)
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“…Pre-surgical evaluation (T1); after preanesthetic medication (MPA); trans-surgical/immediately after hemostasis for the second ovary (T2); after 4 (T3), 24 (T4) and 72 hours from surgical procedures (T5). due to the anaesthetic protocol and fl uid therapy, since the values found were very similar to those presented in a study that evaluated only the changes induced by the protocols (GUEDES et al, 2015). This demonstrates that the bleeding that occurred in both groups did not signifi cantly change the Ht, and consequently, did not cause signifi cant physiological changes.…”
Section: Discussionsupporting
confidence: 65%
See 1 more Smart Citation
“…Pre-surgical evaluation (T1); after preanesthetic medication (MPA); trans-surgical/immediately after hemostasis for the second ovary (T2); after 4 (T3), 24 (T4) and 72 hours from surgical procedures (T5). due to the anaesthetic protocol and fl uid therapy, since the values found were very similar to those presented in a study that evaluated only the changes induced by the protocols (GUEDES et al, 2015). This demonstrates that the bleeding that occurred in both groups did not signifi cantly change the Ht, and consequently, did not cause signifi cant physiological changes.…”
Section: Discussionsupporting
confidence: 65%
“…In Group I (GI, 10,62±4,8kg) the haemostasis method was electrosurgery with laparoscopic bipolar forceps (electrosurgical unit Emai BP150, 150W, forceps 42cm/5mm, EDLO S/A, Rio Grande do Sul, Brazil), and in Group II (GII, 11,2±4,5kg) the method was a laparoscopic clip applier with titanium clips (33cm/10mm, Karl Storz Endoskope, BadenWürttemberg, Germany). The patients were submitted to the anaesthetic and fl uid therapy protocols as described by Guedes et al (2015).…”
Section: Methodsmentioning
confidence: 99%
“…Após a indução anestésica, observou-se redução significativa do hematócrito em ambos os grupos, com redução de 26±11% e 24±7% para G5 e G10, respectivamente, sem diferença numérica. Essa redução inicial do hematócrito já era esperada, pois sabe-se que fármacos vasodilatadores, como os fenotiazínicos e o propofol, podem diminuir significativamente os parâmetros hematológicos como hematócrito (Hauptman et al, 2000;Guedes et al, 2015), hemácias, hemoglobina e leucócitos (Costa et al, 2013;Picioli et al, 2013, provavelmente pelo sequestro de células em sítios não esplênicos (Costa et al, 2013 Tempos: (T1) imediatamente antes da pré-medicação, (T2) 30 minutos após pré-medica o a s a n o anest s ca ao nal o roce ento c r r co a s as atro o to e oras a c r r a. etras a sc las s o t l a as ara ostrar oss e s eren as na linha (entre tratamentos), e letras n sc las ara ostrar oss e s eren as s n cat as na col na entre te os . etras erentes re resenta eren a significativa.…”
Section: Resultsunclassified
“…Por outro lado, em G5 o retorno aos valores basais foi observado a partir de oito horas pós-operatório (T7), quando a média do hematócrito elevou-se para 37,02 ± 5,95%. Apesar de Guedes et al (2015) utilizarem fluidoterapia a 10mL/kg/h por 120 minutos, o retorno aos valores basais de hematócrito foi observado mais precocemente quando comparado ao presente estudo, após quatro horas da cirurgia. Contudo, Guedes et al (2015) não compararam nas mesmas condições clínicas a fluidoterapia a 5mL/kg/h, como no presente estudo, utilizando acepromazina como pré-medicação, a qual pode ter influenciado também no prolongamento da redução do hematócrito.…”
Section: Resultsunclassified