Influence of polymerization temperature on the molecular recognition of imprinted polymers

Ionic Liquids as Porogens in the Synthesis of Molecularly Imprinted Polymers

“…Typically, the MIPs prepared at lower temperature displayed much smoother surfaces. This was anticipated, as it is known that polymerisation temperature has a direct influence on the polymer particle size and porosity (Lu et al, 2004;Kotrotsiou et al, 2009;Li et al, 2007;Rajaram & Hudson, 1996). Interestingly, no fixed correlation between polymer surface area and porosity has been reported for polymers formed in CHCl 3 , with character dependent upon the nature of the template, functional monomer and cross linker used (Li et al, 2007;Kotrotsiou et al, 2009).…”

“…(1) Polymerisation temperature (0 ºC and 60 ºC) as it is has been reported that MIP preparation at low temperature, photoinitiated by UV light, allows for better 'freezing' of the interaction between the template and T-FM pre-polymerisation cluster, leading to an enhanced imprinted framework and improved MIP selectivity (Lu et al 2004). The increased polymerisation rates in RTILs are advantageous here (Andrejewska et al 2009), with some polymerisations failing to proceed in VOCs at 0-5 ºC (Booker 2005).…”

Preparation of Quercetin Molecularly Imprinted Polymers

“…It could be found that Q Qu and D showed the same variation trend, i.e., Q Qu and D increased with the increase of T until T = 45 • C, and then they decreased, while Q IRa presented a monotonously increasing trend. Usually lower temperature would stabilize the template-functional monomers complexes, which would improve the quality and quantity of MIPs recognition sites [20], and further increased the adsorption performance of MIPs. However, if T was too low, the degree of polymerization and cross-linking was low accordingly [21]; thus, Q Qu and Q IRa were low.…”

Chiral separation of 1,1′‐bi‐2‐naphthol and its analogue on molecular imprinting monolithic columns by HPLC

“…With a decrease of sample loading, the enantioseparation factor gradually increases, while the highest resolution is obtained when sample loading is 2.0 lg, which is larger than the value when sample loading is 1.0 lg. The small rise in resolution is due to the sharpening of the peaks as the amount of analyte is increased, which is quickly overcome by the reduction in peak separation at higher sample loading, as the numbers of highaffinity binding sites are limited on surface of MIP [24]. As can been seen from the chromatograms, the peak of (S)-( -)-1,19-bi-2-naphthol is broadening, tailing, and asymmetric as the sample loading is lowered.…”