Influence of phytate level on broiler performance and the efficacy of 2 microbial phytases from 0 to 21 days of age

Santos, Tiago T. dos; Walk, C. L.; Srinongkote, Saksit

doi:10.3382/japr.2013-00842

Cited by 14 publications

(15 citation statements)

References 13 publications

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“…Ca deficiency is not common in commercial chicken production, but there can be problems of malabsorption. For instance, high dietary phytate and fiber in the diet can interfere with Ca absorption ( Selle et al., 2009 , Wilkinson et al., 2011 , dos Santos et al., 2014 , Sadeghi et al., 2015 ). Dietary Ca may also cause malabsorption of trace minerals through precipitation.…”

Section: Introductionmentioning

confidence: 99%

Interactive effect of dietary calcium and phytase on broilers challenged with subclinical necrotic enteritis: 3. Serum calcium and phosphorus, and bone mineralization

et al. 2020

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Calcium is chelated by phytic acid and forms phytate-mineral complexes reducing Ca availability and the ability of phytase to hydrolyze phytate. An increased Ca concentration in the gut favors the activity of Clostridium perfringens ( C. perfringens ). Therefore, it was hypothesized that high dietary calcium with high dietary phytase would decrease serum Ca and P and bone mineralization during necrotic enteritis occurrence. A total of 768 one-day-old Ross 308 male chicks were randomly allocated to 8 treatments with 6 replicate pens, each housing 16 birds. A 2 × 2 × 2 factorial arrangement of treatments was applied: dietary Ca (0.6 or 1.0%), phytase (500 or 1,500 FTU/kg), and challenge (no or yes). Half of the birds (384) were challenged with Eimeria spp. on day 9 and C. perfringens strain EHE-NE18 on day 14 and 15. Blood was collected from 2 birds per pen to determine Ca, P, and parathyroid hormone in the serum. The middle toe, tibia, and femur were excised from 2 birds per pen on day 16 and 29 for determination of ash, breaking strength ( BS ), and mineral concentration. The challenge decreased ( P < 0.05) serum Ca + in birds regardless of dietary Ca level (day 16). There was a challenge × Ca interaction ( P < 0.05) for tibial BS (day 16), with challenge being more severe in birds fed high Ca than low Ca diets. A challenge × phytase interaction ( P < 0.05) was present for femur ash (day 16), with high phytase only increasing ash in challenged birds. The challenge decreased ( P < 0.05) the BS of femur and tibia at each time point. Birds fed high dietary Ca had lower tibial Mg ( P < 0.001), Fe ( P < 0.001), Na ( P < 0.001), and Zn ( P < 0.05) concentrations (day 29). Altogether, high dietary Ca and phytase improved bone mineralization showing that attention to Ca and P nutrition and phytase matrix values is warranted when high levels of phytase are used.

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Section: Introductionmentioning

confidence: 99%

Interactive effect of dietary calcium and phytase on broilers challenged with subclinical necrotic enteritis: 3. Serum calcium and phosphorus, and bone mineralization

et al. 2020

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“…There has been a spate of research about the effect of exogenous phytase in chicken nutrition in recent times, resulting in the heightened application in the poultry industry because of its proven beneficial impacts on the utilization of feed ingredients containing phytic acid ( Angel et al., 2002 ; Wu et al., 2004 ; dos Santos et al., 2014 ; Li et al., 2017 ; Walk and Olukosi, 2019 ). Phytic acid is naturally present in most chicken diets at concentrations of approximately 1%.…”

Section: Introductionmentioning

confidence: 99%

Interactive effect of dietary calcium and phytase on broilers challenged with subclinical necrotic enteritis: part 2. Gut permeability, phytate ester concentrations, jejunal gene expression, and intestinal morphology

et al. 2020

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Calcium has the capacity to interact with phytate-P to form Ca-phytate complexes and decrease the ability of exogenous phytase to degrade phytic acid. This study investigated the hypothesis that high dietary Ca would impair gut permeability, phytate esters (inositol x-phosphate, IPx: IP3, IP4, IP5, and IP6) degradation, jejunal gene expression, and intestinal morphology. Ross 308 day-old male broilers (n = 768) were distributed into 48-floor pens each housing 16 birds in a factorial arrangement. Factors were NE challenge—no or yes; phytase level of 500 or 1,500 FTU/kg, and Ca level 0.6 or 1.0% starter, 0.5 or 0.9% grower, 0.4 or 0.8% finisher with available P in each phase. Challenged birds were gavaged with 3 field strains of Eimeria on day 9 and 10 8 CFU per mL of Clostridium perfringens Strain EHE-NE18 on day 14 and day 15. A phytase × Ca interaction was observed in the ileum for IP3 ( P < 0.01), IP4 ( P < 0.05), and IP6 ( P < 0.01). The IP3 and IP4 concentrations were similar for both doses of phytase in the presence of low Ca, but with high Ca, both increased significantly but to a greater extent when the high dose of phytase was used. While IP6 concentrations were low and similar between both doses of phytase at low Ca levels, increasing dietary Ca levels increased IP6 concentrations regardless of phytase dose, but the effect was greater in the low phytase diet. A phytase × Ca interaction was detected for vitamin D receptor (VDR) ( P < 0.05) expression where bird fed low phytase and low Ca recorded the highest expression of VDR, all other treatments being equivalent. The challenge decreased crypt depth to villus height ratio ( P < 0.001). Challenge birds had higher fluorescein isothiocyanate dextran ( P < 0.05) in blood compared with unchallenged birds. Thus, high Ca and high phytase, while not the best for IP6 destruction, did not lead to huge reductions in indicators of gut health.

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“…a common approach is to use phytases to replace 0.10-0.15% AvP, despite the evidence that modern phytases can potentially offer more complete phytate destruction and much higher P-release than the former counterparts (Van der Klis & Star, 2013;Walk et al, 2013;dos Santos et al, 2014;Zeller et al, 2015). Higher doses of phytase can potentially offer, 1) direct savings in the feed cost through replacing more of an expensive inorganic phosphate, and 2) improved technical performance associated with more complete eRBCA-2019-1217 phytate destruction (dos Santos et al, 2014;Gehring et al, 2013;Walk et al, 2014). In addition to the tangible commercial benefits, the use of higher doses of phytases helps reduce reliance on non-renewable inorganic phosphate reserves (Cordell 2016) and a further reduction in manure P (Kies et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Effect of Graded Levels of an Enhanced E.coli Phytase with Step-Wise Reduction of Supplemental Inorganic Phosphate on Growth Performance of Broilers Fed Corn-Soy Diet

Poernama¹,

Wibowo²,

Gomes

et al. 2020

Braz. J. Poult. Sci.

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This study evaluated the potential of incremental doses of an enhanced Escherichia coli-derived phytase to support step-wise reduction of supplemental inorganic phosphate in an all-vegetable broiler diet. Corn-soybean meal-based diets containing 0.40/0.80%, 0.35/0.70%, and 0.30/0.60% avP and Ca, respectively from 0-10, 10-25, and 26-42 days posthatch served as experimental control (PC). Three test diets were formulated with 500, 1000, and 1500 FTU/kg of phytase assigned respectively an avP matrix of 0.15, 0.19, and 0.23% and a fixed Ca matrix of 0.15%. An additional diet (PC++) containing extra avP and Ca (+0.05% avP/+0.1% Ca) to that of PC was included to test if avP and Ca were not limiting in PC. Each diet was offered to 16 replicates of straight-run broilers kept in floor pens (30 birds per pen). PC++ had lower (p<0.05; 10 and 25 d) or similar (42 d) BW and toe ash compared with PC confirming the avP and Ca set in PC were sufficient to support optimal growth and bone mineralization. Compared to the PC, diets containing 1000 and 1500 FTU phytase had higher BW (p<0.05) at 10 and 25 d. For the overall period of 0-42 d, FI, BW and FCR did not differ across treatments. Percentage-, but not the absolute-, toe ash at phytase treated groups was significantly (p<0.05) low compared with the PC. The experiment demonstrated that 1500 FTU/kg of enhance E. coli phytase supports optimal BW and FCR of broilers fed corn-soy diet largely void of supplemental inorganic phosphate.

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Influence of phytate level on broiler performance and the efficacy of 2 microbial phytases from 0 to 21 days of age

Cited by 14 publications

References 13 publications

Interactive effect of dietary calcium and phytase on broilers challenged with subclinical necrotic enteritis: 3. Serum calcium and phosphorus, and bone mineralization

Interactive effect of dietary calcium and phytase on broilers challenged with subclinical necrotic enteritis: 3. Serum calcium and phosphorus, and bone mineralization

Interactive effect of dietary calcium and phytase on broilers challenged with subclinical necrotic enteritis: part 2. Gut permeability, phytate ester concentrations, jejunal gene expression, and intestinal morphology

Effect of Graded Levels of an Enhanced E.coli Phytase with Step-Wise Reduction of Supplemental Inorganic Phosphate on Growth Performance of Broilers Fed Corn-Soy Diet

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