Influence of particle size of mesoporous silica composite nanoparticles coated with pH/temperature responsive copolymer on ibuprofen release behaviors

Jin, Xiaoqi; Xiong, Mingwen; Zhu, Linlin; Zhang, Liyuan; Wu, Zhong

doi:10.1080/01932691.2020.1843479

Cited by 3 publications

(3 citation statements)

References 47 publications

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“…Comparably, for HSMs(DC)-0.15-NH2, a 5, the weight loss was enhanced, and a weight loss of approximate HSMs(DC)-0.15-NH2 was recorded within the range of 200-800 °C. Th As can be seen, it was observed that the weight loss of all samples before reaching 200 • C was attributed to the adsorbed water molecules and the residual solvent [46]. Furthermore, Figure 5 shows that the weight loss of approximately 2.92 wt% for HSMs(DC)-0.15 was recorded within the range of 200-800 • C, which generally corresponded to the dehydration of the silanol groups in the pore channels and residue of organic components.…”

Section: Structural and Textural Featuresmentioning

confidence: 83%

“…Figure 5 reveals the TGA profiles of HSMs(DC)-0.15, HSMs(DC)-0.15-APTES, HSMs(DC)-0.15-NTPEA, and HSMs(DC)-0.15-NH 2 .As can be seen, it was observed that the weight loss of all samples before reaching 200 • C was attributed to the adsorbed water molecules and the residual solvent[46]. Furthermore, Figure5shows that the weight loss of approximately 2.92 wt% for HSMs(DC)-0.15 was recorded within the range of 200-800 • C, which generally corresponded to the dehydration of the silanol groups in the pore channels and residue of organic components.…”

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confidence: 95%

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Synthesis of Hierarchically Ordered Porous Silica Materials for CO2 Capture: The Role of Pore Structure and Functionalized Amine

Jin

Zhang

et al. 2022

Inorganics

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Hierarchically ordered porous silica materials (HSMs) with a micro/mesoporous structure were successfully prepared with the sol-gel method using dextran, dextran/CTAB, and CTAB as templates. The obtained hierarchically structured silica was successfully modified with amine groups through post-grafting and one-pot methods. Their architectural features and texture parameters were characterized by XRD, N2 adsorption–desorption isotherms, SEM, TEM, FTIR, and TGA techniques. The results demonstrated that the pore structure depended on the reaction temperature and the amount of CTAB added in the synthesis procedure. A series of porous silica with hierarchical pore structures possessed abundant micropores, ordered mesopores, and a tunable surface area and pore volume. After modification, the ordered structure of the hierarchical porous silica almost disappeared due to the presence of amine groups in the pore channel. Furthermore, to explore the effect of pore structures and amine groups on CO2 adsorption performance, before and after amine modification of HSMs, adsorbents were evaluated regarding the capacity of collecting CO2 for comparison. According to these results, the varying microporous content, pore size distribution, and density of the amine groups were important factors determining the capacity of CO2 capture.

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Section: Structural and Textural Featuresmentioning

confidence: 83%

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confidence: 95%

Synthesis of Hierarchically Ordered Porous Silica Materials for CO2 Capture: The Role of Pore Structure and Functionalized Amine

Jin

Zhang

et al. 2022

Inorganics

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“…In recent years, nanocarrier materials have received extensive research because they have small particles [13], low toxicity, high biocompatibility [14], and high chemical stability [15]. Among these nanocarriers, the mesoporous silica nanoparticles (MSNs) show a series of significant advantages, such as excellent biocompatibility [15], easy synthesis [16], large surface area [17], excellent chemical stability [18], unique mesoporous structure [19], easy functionalization [20], and chemical inertness [21], attracting widespread attention.…”

Section: Introductionmentioning

confidence: 99%

Redox-responsive mesoporous silica nanoparticles for chemo- photodynamic combination cancer therapy

Zhu

Zhang

Song

et al. 2022

Mater. Res. Express

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Traditional chemotherapy remains the primary cancer treatment, but it shows low enrichment and non-specificity. Hence, we have designed a multifunctional nanocarrier based on glutathione (GSH)-responsive mesoporous silica nanoparticles (MSNs). Firstly, disulfide bonds were linked on the surface of mesoporous silica. Then, doxorubicin (DOX) and chlorin e6 (Ce6) were co-loaded into the pores. Finally, carboxymethyl chitosan (CMCS) coated the nanoparticles to obtain the DOX/Ce6@MSN-SS-CMCS (DOX/Ce6@MSC) nanocarrier. The synthesized DOX/Ce6@MSC showed good monodispersity, dimensional stability, and consistent spectral characteristics. DOX/Ce6@MSC could effectively enter cancer cells and successfully deliver drugs. Under 660 nm laser irradiation, DOX/Ce6@MSC exhibited an effective photodynamic therapy effect that resists MCF-7 cells by triggering reactive oxygen species production. Thereby, it could efficiently inhibit cell proliferation and induce cell death. Anticancer analysis of tumor-bearing mice demonstrates that the DOX/Ce6@MSC combination treatment induced cell apoptosis effectively and showed an excellent antitumor effect in vivo. Therefore, DOX/Ce6@MSC nano-drug delivery system could be an effective strategy in cancer treatment.

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Preparation and evaluation of controllable drug delivery system: a pH and temperature responsive nanosphere based on chitosan copolymer/mesoporous silica

Wang,

Jiang,

Shang

et al. 2023

J Polym Res

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Influence of particle size of mesoporous silica composite nanoparticles coated with pH/temperature responsive copolymer on ibuprofen release behaviors

Cited by 3 publications

References 47 publications

Synthesis of Hierarchically Ordered Porous Silica Materials for CO2 Capture: The Role of Pore Structure and Functionalized Amine

Synthesis of Hierarchically Ordered Porous Silica Materials for CO2 Capture: The Role of Pore Structure and Functionalized Amine

Redox-responsive mesoporous silica nanoparticles for chemo- photodynamic combination cancer therapy

Preparation and evaluation of controllable drug delivery system: a pH and temperature responsive nanosphere based on chitosan copolymer/mesoporous silica

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