Influence of organic selenium supplementation on the accumulation of toxic and essential trace elements involved in the antioxidant system of chicken

Pappas, Athanasıos C.; Zoidis, Evangelos; Georgiou, Constantınos A.; Demiris, Nıkos; Surai, Peter F.; Fegeros, K.

doi:10.1080/19440049.2010.549152

Cited by 55 publications

(23 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a previous study In T1 treatment, broilers were fed a diet with 0.3 mg/kg added Se, as Se-yeast, without added Cd; in T2, broilers were fed a diet with 0.3 mg/kg Se and 10 mg/kg Cd; in T3, broilers were fed a diet with 0.3 mg/kg Se and 100 mg/kg of Cd; and in T4 treatment broilers were fed a diet with 3 mg/kg Se and 100 mg/kg Cd. (Pappas et al, 2011), it was shown that Se-yeast added at several concentrations, from 0.15 up to 3 mg/kg, could reduce the tissue deposition of the low Cd levels (no added Cd, only that present in the diet). It is possible that the discrepancy of the results reported in the present work and the previous study by Pappas et al (2011) is related to the ratio of Se/Cd.…”

Section: Discussionmentioning

confidence: 99%

“…(Pappas et al, 2011), it was shown that Se-yeast added at several concentrations, from 0.15 up to 3 mg/kg, could reduce the tissue deposition of the low Cd levels (no added Cd, only that present in the diet). It is possible that the discrepancy of the results reported in the present work and the previous study by Pappas et al (2011) is related to the ratio of Se/Cd. It is possible that 3 mg/kg of added Se could not ameliorate all the toxic effects of 100 mg/kg of added Cd.…”

Section: Discussionmentioning

confidence: 99%

“…Se and Cd determination Se and Cd were determined in feed and tissue samples using inductively coupled plasma mass spectrometry, ICP-MS (Perkin Elmer, Elan 9000, Perkin Elmer Life and Analytical Sciences Inc., Waltham, MA, USA; Pappas et al, 2011). The instrumental parameters of the equipment used were: nebulizer flow 0.775 l/min, vacuum pressure 1.5 3 10 25 Torr, lens voltage 950 W, analogue stage voltage 1900 V, pulse stage voltage 950 V, sweeps/reading 20, readings/replicate 1, number of replicates 3, time per sample 83 s. Feed samples were collected before feeding and milled before analysis through a 1 mm sieve (Cyclotec, 1093 sample mill, Tecator, Hö ganä s, Sweden).…”

Section: Animals Diets and Experimental Designmentioning

confidence: 99%

See 2 more Smart Citations

The role of organic selenium in cadmium toxicity: effects on broiler performance and health status

Al-Waeli

Zoidis

Pappas

et al. 2013

Animal

View full text Add to dashboard Cite

This work was part of a project designed to assess whether organic selenium (Se) can protect against the toxic effects of cadmium (Cd). A total of 300 1-day-old, as hatched, broilers were randomly distributed in four dietary treatments with five replicate pens per treatment. In T1 treatment, broilers were fed a diet with 0.3 mg/kg added Se, as Se-yeast, without added Cd; in T2, broilers were fed a diet with 0.3 mg/kg Se and 10 mg/kg Cd; in T3, broilers were fed a diet with 0.3 mg/kg Se and 100 mg/kg of Cd; and in T4 treatment broilers were fed a diet with 3 mg/kg Se and 100 mg/kg Cd. The Cd was added to diets T2, T3 and T4 as CdCl 2 . On the 4th and 6th week, two broilers per replicate pen were killed in order to obtain whole blood, liver, kidney and breast samples. Body mass, feed conversion ratio and mortality were assessed and haematological analyses were performed. Se and Cd levels in tissues were analysed by inductively coupled plasma mass spectrometry. Broilers supplemented with 0.3 mg/kg Se can tolerate low levels of Cd added to the diets, as there were no significant negative effects on the examined performance parameters, whereas addition of excess Cd led to an impairment of broilers' performance. Mortality of broilers did not differ between the four dietary treatments at any interval point or the whole period. The examined haematological parameters such as haematocrit, total blood protein concentration, and leukocytes types ranged within physiological values, revealing no negative health effects after simultaneous Cd and Se addition. The present study indicated that Se can help against the negative effects of Cd, but cannot counteract all of its negative effects.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Animals Diets and Experimental Designmentioning

confidence: 99%

See 1 more Smart Citation

The role of organic selenium in cadmium toxicity: effects on broiler performance and health status

Al-Waeli

Zoidis

Pappas

et al. 2013

Animal

View full text Add to dashboard Cite

show abstract

“…Deficiency or supplementation of an element may alter their balance and trigger antagonistic or synergistic effects. The alteration of trace element balance may concomitantly affect the antioxidant defense system as several trace elements, such as Se, Cu, Fe and Zn, are integral part of various antioxidant enzymes (Pappas et al, 2011). Future studies should take into account Se speciation.…”

Section: Discussionmentioning

confidence: 99%

Meta-analysis of selenium accumulation and expression of antioxidant enzymes in chicken tissues

Zoidis

Demiris

Kominakis

et al. 2014

Animal

View full text Add to dashboard Cite

A meta-analysis integrating results of 40 selenium (Se) supplementation experiments that originated from 35 different controlled randomized trials was carried out in an attempt to identify significant factors that affect tissue Se accumulation in chicken. Examined factors included: Se source (12 different sources examined), type of chicken (laying hens or broilers), age of birds at the beginning of supplementation, duration of supplementation, year during which the study was conducted, sex of birds, number of chickens per treatment, method of analysis, tissue type, concentration of Se determined and Se added to feed. A correlation analysis was also carried out between tissue Se concentration and glutathione peroxidase activity. Data analysis showed that the factors significantly affecting tissue Se concentration include type of chicken ( P = 0.006), type of tissue ( P < 0.001) and the analytical method used ( P = 0.014). Although Se source was not found to affect tissue Se concentration (overall P > 0.05), certain inorganic (sodium selenite), calcium selenite, sodium selenate and organic sources (B-Traxim Se), Se-yeast, Se-malt, Se-enriched cabbage and Se-enriched garlic as well as background Se level from feed ingredients were found to significantly affect tissue Se concentration. The Se accumulation rate (estimated as linear regression coefficient of Se concentrations to Se added to feed) discriminated between the various tissues with highest values estimated in the leg muscle and lowest in blood plasma. Correlation analysis has also shown that tissue Se concentration (pooled data) was correlated to Se added to feed (r = 0.529, P < 0.01, log values) and to glutathione peroxidase activity (r = 0.332, P = 0.0478), with the latter not being correlated with Se added to feed. Although significant factors affecting Se concentration were reported in the present study, they do not necessarily indicate the in vivo function of the antioxidant system or the level of accumulated Se as other factors, not examined in the present study, may interact at the level of trace element absorption, distribution and retention.

show abstract

“…The sensitivity for the T 3 assay was 0.1 ng/ml, whereas that for T 4 1.8 ng/ml. Intra-and inter assay coefficients of variation were 2.9 Finally, Se concentration was determined in plasma using inductively coupled plasma mass spectrometry, ICP-MS (Perkin Elmer, Elan 9000, Perkin Elmer Life and Analytical Sciences Inc, Waltham, MA, USA) as described previously (Pappas et al, 2011).…”

Section: Methodsmentioning

confidence: 99%

Effects of concomitant selenium and vitamin E administration on thyroid hormone metabolism in broilers

Pappas

Kotsampasi

Kalamaras

et al. 2018

J Hellenic Vet Med Soc

View full text Add to dashboard Cite

show abstract

Influence of organic selenium supplementation on the accumulation of toxic and essential trace elements involved in the antioxidant system of chicken

Cited by 55 publications

References 50 publications

The role of organic selenium in cadmium toxicity: effects on broiler performance and health status

The role of organic selenium in cadmium toxicity: effects on broiler performance and health status

Meta-analysis of selenium accumulation and expression of antioxidant enzymes in chicken tissues

Effects of concomitant selenium and vitamin E administration on thyroid hormone metabolism in broilers

Contact Info

Product

Resources

About