Influence of mineral metabolism parameters on pulse pressure in healthy subjects

Muray, S; Mp, Marco; Craver, Lourdes; M, Rue; Valdivielso, José M.; Fernández, E

doi:10.5414/cnp66411

Cited by 9 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is in line with other studies indicating that 25-(OH)D levels in Mediterranean countries, 12,55,[59][60][61][62][63][64] and in Greece specifically, 28,64 are often surprisingly low, with reported levels as low as 9.4 ng/mL in males and 8.5 ng/mL in females in autumn. 65 Our results are also in agreement with published reports suggesting that insolation in a certain region may not be the sole, or even an accurate, predictor of the VitD status. 28,59,66,67 Along the same lines, an unexpected inverse north-south gradient for VitD levels in Europe is often reported, 41,59 with 25-(OH)D levels positively correlated with latitude, and is primarily attributed to dietary habits (higher consumption of VitD-rich foods in the north), supplementation (Greece presented the lowest mean supplement intake, 2% in men and 6.7% in women), 68 and differences in the population's skin pigmentation.…”

Section: Discussionsupporting

confidence: 83%

Vitamin D levels in a large Mediterranean cohort: reconsidering normal cut-off values

Katrinaki

Kampa

Margioris

et al. 2016

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 83%

Vitamin D levels in a large Mediterranean cohort: reconsidering normal cut-off values

Katrinaki

Kampa

Margioris

et al. 2016

View full text Add to dashboard Cite

“…A similar tendency was found for PP in their follow-up study of Caucasian men with the BsmI genotype. No such association was found in women ( 35 ) . These studies suggest that the combined effect of BsmI vitamin D receptor gene polymorphisms and circulating 25(OH)D on BP may be altered by oestrogen ( 8 , 35 ) .…”

Section: Discussionmentioning

confidence: 80%

“…No such association was found in women ( 35 ) . These studies suggest that the combined effect of BsmI vitamin D receptor gene polymorphisms and circulating 25(OH)D on BP may be altered by oestrogen ( 8 , 35 ) . In addition, Argiles et al ( 16 ) observed a positive association between systolic and diastolic BP and seasonal variations of circulating 25(OH)D among haemodialysis patients (mean age: 56 years).…”

Section: Discussionmentioning

confidence: 80%

Circulating 25-hydroxyvitamin D levels in relation to blood pressure parameters and hypertension in the Shanghai Women's and Men's Health Studies

et al. 2012

View full text Add to dashboard Cite

Little is known about the association of circulating 25-hydroxyvitamin D (25[OH]D) and blood pressure (BP) parameters, and hypertension in non-Western populations that have not yet been exposed to foods fortified with vitamins and seldom use vitamin D supplements. A cross-sectional analysis of plasma 25(OH)D levels in association with BP measures was performed for 1460 participants (405 men and 1055 women, aged 40–75 years) of two large cohort studies in Shanghai. Multivariable linear and logistic regressions were conducted. Overall, the prevalence of vitamin D deficiency was 55.8% using NHANES/USA criteria and 29.9% using WHO criteria. The median plasma 25(OH)D level was 38.0 nmol/L for men and 33.6 nmol/L for women (P<0.01) among subjects who were not on antihypertensive drugs. Among men, BP parameters (systolic BP, diastolic BP, and MAP) were significantly and inversely associated with higher quintiles of 25(OH)D compared with the lowest quintile (Ptrend <0.05 for all). Vitamin D non-deficient status (WHO criteria) was inversely associated with hypertension (ORadj =0.29, 95% CI: 0.10–0.82). An inverse association was also found between hypertension and the highest quintile of 25(OH)D (ORadj =0.16, 95% CI: 0.04–0.65 for ≥50.6 nmol/L; Ptrend =0.02). Among women, no significant associations were found for BP parameters and hypertension. The present study shows that vitamin D deficiency is common among adults in urban China. Circulating 25(OH)D levels were inversely related to levels of individual BP parameters and hypertension among middle-aged and elderly men but not in women. More research is needed to investigate the potential gender differential associations.

show abstract

“…This state of calciferol insufficiency is replicated in Spain, with results which we show in table 1 [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38] . The interlaboratory variation in the different methodologies used makes a rigorous comparison difficult, but the table illustrates clearly that, in spite of a theoretical climatological ease of vitamin D synthesis in Spain, the levels are similar to, or even lower than those reported for central Europe or Scandinavia, as has been described in earlier works 39 .…”

Section: State Of Vitamin D Insufficiency In Spainmentioning

confidence: 86%

“…Most of Spain is above the 35ºN parallel where the possibility of synthesising vitamin D in winter and spring is low, and because most Spanish people have darker skin which makes the synthesis of vitamin D more difficult 39 . We observed that in Spain, as in the rest of the world, insufficiency, or even true deficiency in vitamin D is already found in children or young people, and persists in adults, postmenopausal women (osteoporotic or not), and in older people who live in their own homes, and that it is even higher if they live in residential homes, with a seasonal variation which barley reaches normal levels after summer-autumn [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39] . Although this high prevalence of low levels of vitamin D occurs due to inadequate exposure to sunlight, in older Spanish people lower levels have been described in the summer months due to the high temperatures which occur in the cities of southern Spain such as Murcia or Cordoba at this time of year, which are commonly between 30 and 40° C. The older people avoid being in the sun and prefer to remain indoors where the temperature is more comfortable.…”

Section: State Of Vitamin D Insufficiency In Spainmentioning

confidence: 99%

Deficiencia de vitamina D en España: ¿realidad o mito?

Valverde

Gómez

2014

Rev Osteoporos Metab Miner

View full text Add to dashboard Cite

Vitamin D 3 (colecalciferol) is formed from its precursor 7-dehydrocholesterol in the skin by ultraviolet irradiation. In the liver the vitamin D 3 is hydroxylated to form 25-hydroxyvitamin D 3 , which is metabolised to its active metabolite 1,25-dihydroxyvitamin D 3 preferentially in the kidney. Vitamin D 3 may also be provided in the diet, which is a significant source of supply only in the case of insufficient exposure to sunlight. Blue fish naturally contains large quantities of vitamin D 3 , while other foods contain significant quantities of vitamin D only after being fortified. For fortification, in many countries vitamin D 2 is used (ergocalciferol) obtained from vegetable sources 1 . The presence of the enzyme CYP27B1, which drives the synthesis of dihydroxyvitamin D from its principal substrate, 25-hydroxyvitamin D, and the vitamin D receptor (VDR), distributed almost universally in the cells and tissues of the organism, confers on vitamin D (although it would be increasingly more correct to say the endocrine system of vitamin D) a broad role in health. This is not only in the regulation of calcium and bone metabolism but also in relation to the cardiovascular system, innate or acquired immunomodulation, the regulation of cell growth, etc., such that around 3% of the human genome is regulated by the hormone 1,25(OH) 2 vitamin D 3 1-3 . It is therefore not surprising that basic scientific and clinical interest in vitamin D 4 , as well as interest in the non-specialist press and in the general population 5 , has increased almost exponentially in the last decade. 25-hydroxyvitamin D, marker for the status of vitamin D in the bodyFor some years there has been universal consensus that the measurement of the levels of the metabolite 25-hydroxyvitamin D in the blood is the marker for the status of vitamin D in the body, including the endogenous synthesis due to exposure to sunlight, dietary consumption in foods, supplemented or not, and pharmacological treatments 1,2

show abstract

Influence of mineral metabolism parameters on pulse pressure in healthy subjects

Cited by 9 publications

References 0 publications

Vitamin D levels in a large Mediterranean cohort: reconsidering normal cut-off values

Vitamin D levels in a large Mediterranean cohort: reconsidering normal cut-off values

Circulating 25-hydroxyvitamin D levels in relation to blood pressure parameters and hypertension in the Shanghai Women's and Men's Health Studies

Deficiencia de vitamina D en España: ¿realidad o mito?

Contact Info

Product

Resources

About