Influence of leisure activity on the incidence of Alzheimer’s Disease

Abstract

The data suggest that engagement in leisure activities may reduce the risk of incident dementia, possibly by providing a reserve that delays the onset of clinical manifestations of the disease.

The impact of cognitive training and mental stimulation on cognitive and everyday functioning of healthy older adults: A systematic review and meta-analysis

“…A c c e p t e d M a n u s c r i p t 4 Epidemiological evidence suggests that higher levels of engagement in mental stimulation are associated with lower rates of cognitive decline (Scarmeas et al, 2001;Wilson et al, 2002a;Wilson et al, 2002b;Wilson et al, 2007), with less decline specifically noted in working memory and processing speed (Wilson et al, 2002b). However most of the evidence to date is correlational and only a limited number of RCTs have examined the efficacy of mental stimulation on cognition.…”

Healthy Brain Aging: Role of Exercise and Physical Activity

“…Participation in physical activity may thus lower the risk of cognitive decline and dementia by improving cognitive reserve. 13,15,16,18,50,89,90 Higher cognitive reserve may help the subject engage in regular physical activity to cope with the first cognitive symptoms of AD. This effect may delay the onset of the clinical manifestations of the disease, which may become apparent only later.…”

Cognitive reserve: Implications for diagnosis and prevention of Alzheimer’s disease

“…Nevertheless, many other cohorts have reported that physical activities provide protection for future cognitive decline [8,32,[52][53][54][55][56]. In addition, high levels of physical activity were associated with reduced risk of dementia in at least four prospective studies [21,[57][58][59]. Decreased risk for cognitive decline has been reported not only for strenuous [32] but also moderate physical activities [55,57].…”