Influence of Fluoride Availability of Dentifrices on Eroded Enamel Remineralization in situ

Abstract

Remineralization of eroded enamel by dentifrices containing similar sources/concentrations of fluoride was investigated in situ. Fifty-three subjects completed a double-blind crossover study with 3 randomly assigned dentifrice treatments: placebo (0 ppm F, PD); reference (1,450 ppm NaF, RD) and test (1,450 ppm NaF + 5% KNO₃, TD). Fluoride availability for each dentifrice was analyzed in vitro by standard tests (1-min fluoride release rate and enamel fluoride uptake). The subjects wore palatal appliances holding bovine enamel specimens previously eroded in vitro. Surface microhardness was determined before and after the in vitro erosive challenge, after in situ remineralization and after a second in vitro erosive challenge. ANOVA and pairwise comparisons were performed (α = 0.05). TD was superior to RD in the fluoride release tests, but similar to RD in the enamel fluoride uptake test. The mean percent surface microhardness recovery was 21.9 (standard deviation 8.0) for PD, 28.6 (8.0) for RD and 36.0 (8.0) for TD. The mean percent relative erosion resistance change was –58.8 (12.7) for PD, –31.3 (12.7) for RD and –27.3 (12.6) for TD. Both fluoride-containing dentifrices provided superior remineralization (p < 0.001) and erosion resistance (p < 0.001) compared to PD. The percent surface microhardness recovery demonstrated by the TD was significantly greater than for the RD (p < 0.001). There was no significant difference (p = 0.073) between TD and RD in relative resistance to further erosive challenge. The results suggest that fluoride availability may be different in dentifrices with similar sources/concentrations of fluoride, providing different levels of remineralization of eroded enamel.

Effects of enamel abrasion, salivary pellicle, and measurement angle on the optical assessment of dental erosion

“…Furthermore, fluoride was often added into the remineralization solution at higher concentrations than those found in human saliva (0.022 ppm) 49 because its profound effect on the enamel remineralization is well-established in the field. 34,61,62 It could be possible that the application of the more efficient remineralizing agents such as higher concentrations of fluoride and metal compounds (Sn 2þ , Ti 2þ ) 63 would result in the detection of erosion inhibition by reflection analysis.…”

AmF/NaF/SnCl2 solution reduces in situ enamel erosion – profilometry and cross-sectional nanoindentation analysis

“…In order to protect the slabs from the abrasive influence of the tongue or buccal mucosa, each slab was fixed approximately 0.5 mm below the surface of the appliance. 21 Within each side of the mandibular appliance, the positions of the specimens were randomly determined. The specimens were maintained in 100% humidity until the in situ experiment was conducted.…”

Hipersensibilidade dentinária cervical: Uma Revisão da Literatura

“…Estas lesões são denominadas lesões cervicais 4,5 . Para a perda de estrutura dentária alguns dos tratamentos apresentados não são eficazes, porém há terapias efetivas como: aplicação de oxalato de potássio, de cloreto de estrôncio, de vernizes fluorados, de fluoreto de sódio, de laser, de dentifrícios dessensibilizantes, de sistemas adesivos e de procedimentos restauradores 6,7 . Portanto, a identificação e a remoção dos fatores etiológicos são essenciais ao sucesso do tratamento da HSDC, quando associadas à obliteração dos túbulos dentinários, tendo-se como resultado a efetiva redução do movimento do fluído dentro desses e a diminuição da dor 2,8 .…”