Influence of experimental hypothermia on exocrine pancreatic secretion in anaesthetized rabbits

Pancreatic Secretion by the Anaesthetized Rabbit in Response to Secretin, Cholecystokinin, and Carbachol

“…Early studies in anaesthetized animals showed it to possess a true spontaneous secretion (5), which could be augmented by vagal stimulation or intravenous acetylcholine (6). Between 1965 and the present, a number of studies have been published on anaesthetized rabbit, in which some aspects of pancreatic electrolyte secretion have been measured (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22). In these studies, very considerable variations in the volume and composition of spontaneous and secretin-stimulated pancreatic juice are recorded, while in only four has the effect of CCK on fluid secretion been briefly mentioned (9,13, 16,18).…”