Influence of embryo transfer depth on in vitro fertilization and embryo transfer outcomes

Pope, Christian S.; Cook, Elizabeth; Arny, M.; Novak, Amy; Grow, Daniel R.

doi:10.1016/j.fertnstert.2003.05.030

Cited by 139 publications

(116 citation statements)

References 31 publications

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“…So a deep fundal transfer as well as the quantity of serum fluid used for ET increased the risk of EP [24]. A greater transfer distance from the fundus led to a significantly increased PR as well as lower ectopic rates [25].…”

Section: Resultsmentioning

confidence: 99%

Previous tubal ectopic pregnancy raises the incidence of repeated ectopic pregnancies in In Vitro fertilization-embryo transfer patients

Weigert

Gruber

Pernicka

et al. 2008

J Assist Reprod Genet

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Purpose To investigate the incidence of Tubal Ectopic Pregnancies (TEP) in IVF-ET patients with respect to the status of the fallopian tubes after a previous TEP. Material and methods This retrospective study compares patients undergoing 481 IVF-ET cycles after conservatively or surgically treated TEP(s) with a Control Group (idiopathic or male factor for IVF-ET indication). Medical reports of surgery and/or hysterosalpingograms prior to the IVF cycles classified the status of the fallopian tubes. Results 12 TEPs (8.95%/Pregnancies (PR)) occurred in the Study Group. In the Control Group one TEP (0.75%/PR; p<0.001) was found. Smoking increased the probability of TEPs (p=0.0028) and of pathological pregnancies (abortion, biochemical and ectopic PR; (p=0.0411)). For statistic evolution logistic regression (PROC GENMOD) and a repeated measure model were applied. Conclusion Women with a previous TEP should be informed about the significantly increased risk for a further TEP in IVF-ET treatment, especially if they are smoking.

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Section: Resultsmentioning

confidence: 99%

Previous tubal ectopic pregnancy raises the incidence of repeated ectopic pregnancies in In Vitro fertilization-embryo transfer patients

Weigert

Gruber

Pernicka

et al. 2008

J Assist Reprod Genet

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“…Several studies have recently analyzed variables affecting successful ET such as US-guided ET, mock transfer, type of catheter, loading the catheter, blood or mucus effects, retained embryos, uterine contractions, and facility of the procedure. Studies which evaluated the effect of US-guided ET indicated that US-guided ET appears to improve IVF success and is significantly associated with increased PRs [5][6][7][8]. However, during US-guided ET the ultrasonographic visualization of newer ET catheters and air bubbles, an identifier of the position of the embryos, is one of the most important developments regarding ET technique.…”

Section: Discussionmentioning

confidence: 99%

“…A targeted successful ET prevents endometrial injury and the induction of uterine contractions; it protects embryos and places embryos in an optimal position within the uterine cavity, thus maximizing embryo implantation. Ultrasound (US)-guided ET can overcome adverse effects including endometrial injury and the induction of uterine contractions during ET and it can determine ET depth and the location of air bubbles [5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Can the Movement of the Air Bubbles After Embryo Transfer Predict the Success of IVF Treatment?

Özcan¹

2016

Ann Clin Anal Med

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“…Physiologic uterine contractility strongly suggested that bubble placement and location may change 30 minutes following embryo transfer [4]. If indeed uterine contractility changes the movement of embryos or disperses the marker bubble, the common belief that accurate placement of embryos is crucial for IVF success rates is challenged [5]. Individual talent and performance of ET by various providers may considerably vary, affect pregnancy rates [6], and alter air bubble ejection technique.…”

Section: Introductionmentioning

confidence: 99%

Air bubble migration is a random event post embryo transfer

Confino

Zhang

Rísquez

2007

J Assist Reprod Genet

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Introduction: Air bubble location following embryo transfer (ET) is the presumable placement spot of embryos. The purpose of this study was to document endometrial air bubble position and migration following embryo transfer.Design: Multicenter prospective case study. Materials and Methods: Eighty-eight embryo transfers were performed under abdominal ultrasound guidance in two countries by two authors. (EC, FR) A single or double air bubble was loaded with the embryos using a soft, coaxial, end opened catheters. The embryos were slowly injected 10-20 mm from the fundus. Air bubble position was recorded immediately, 30 minutes later and when the patient stood up.Results: Bubble marker location analysis revealed a random distribution without visible gravity effect when the patients stood up. The bubble markers demonstrated splitting, moving in all directions and dispersion.Conclusion: Air bubbles move and split frequently post ET with the patient in the horizontal position, suggestive of active uterine contractions. Bubble migration analysis supports a rather random movement of the bubbles and possibly the embryos. Standing up changed somewhat bubble configuration and distribution in the uterine cavity. Gravity related bubble motion was uncommon, suggesting that horizontal rest post ET may not be necessary. This report challenges the common belief that a very accurate ultrasound guided E. Confino ( ) ·

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Influence of embryo transfer depth on in vitro fertilization and embryo transfer outcomes

Cited by 139 publications

References 31 publications

Previous tubal ectopic pregnancy raises the incidence of repeated ectopic pregnancies in In Vitro fertilization-embryo transfer patients

Previous tubal ectopic pregnancy raises the incidence of repeated ectopic pregnancies in In Vitro fertilization-embryo transfer patients

Can the Movement of the Air Bubbles After Embryo Transfer Predict the Success of IVF Treatment?

Air bubble migration is a random event post embryo transfer

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