Influence of disease activity on functional capacity in patients with rheumatoid arthritis

Jovanović, Jelena; Stojanović, Miodrag; Jovanović, Vladimir; Dimić, Aleksandar; Bozilov, S.; Stamenković, Bojana; Milenković, Saša

doi:10.2298/vsp1501021j

Cited by 6 publications

(5 citation statements)

References 11 publications

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“…A study assessing functional disability in women with RA found that all the participants needed assistive devices to carry out normal daily tasks, most frequently for eating, gripping, and hygiene (Nordenskiold and Grimby, 1997). Our unadjusted regression results agree with studies that find CRP concentration to be related to functional impairment in individuals with RA (Jovanovic et al, 2015; Lisitsyna et al, 2013). One study found that CRP concentrations were significantly related to severe pain perception in RA patients, which likely impacts their ability to perform tasks (Lisitsyna et al, 2013).…”

Section: Discussionsupporting

confidence: 91%

“…One study found that CRP concentrations were significantly related to severe pain perception in RA patients, which likely impacts their ability to perform tasks (Lisitsyna et al, 2013). Jovanovic et al reported that the presence of elevated CRP concentrations increased the odds of having the most severe functional status impairment assessed using the HAQ (Jovanovic et al, 2015). However, since inflammation is associated with adiposity, including BMI in our adjusted model likely influenced the significance of the CRP concentration coefficient (Choi et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

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Diet quality of individuals with rheumatoid arthritis using the Healthy Eating Index (HEI)-2010

et al. 2017

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Diet quality of individuals with rheumatoid arthritis using the Healthy Eating Index (HEI)-2010

et al. 2017

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“…Female sex was associated with worse disability in this study, which is consistent with the prior studies 6,11 . Not unexpectedly, patients with RF/CCP-positive status as a marker of severe disease experienced increasing FD over the RA duration, a finding consistent with previous observations in some studies [14][15] , but not in others 8 .…”

Section: Discussionsupporting

confidence: 89%

Trends in Prevalence of Functional Disability in Rheumatoid Arthritis Compared With the General Population

Myasoedova

Davis

Achenbach

et al. 2019

Mayo Clinic Proceedings

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The objective of the study was to assess trends in functional disability (FD) in rheumatoid arthritis (RA) versus non-RA subjects. This retrospective population-based study included patients with RA (n=586) and non-RA subjects (n=531). Activities of Daily Living (ADL) were obtained from self-report questionnaires. The prevalence of FD was higher in RA (26%) versus non-RA subjects (11%) at RA incidence/index date (p<0.001), with persistent excess over the follow-up and calendar time. RA patients had ≥15%-higher prevalence of FD than the non-RA subjects in most age-groups. Patients with RA have higher prevalence of FD across RA duration, age and calendar time than non-RA subjects.

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“…Finding women to have increased HAQ-DI and DAS28 scores was not presented in other studies and warrants further investigation. As HAQ-DI and pain are measures of functional status as well as disease activity, a strong correlation between measures of disease activity exhibited significant correlation with one another (not shown) supports previous evidence of a relationship between high CRP scores and decreased functional status (Berube et al, 2017; Jovanovic et al, 2015) and patient report of pain (Lisitsyna et al, 2013).…”

Section: Discussionsupporting

confidence: 83%

Diet quality and disease activity in rheumatoid arthritis

et al. 2021

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Objective:This study examined associations between diet quality and disease activity in adults with rheumatoid arthritis (RA). Perceived stress was also compared to diet and disease activity. Methods: In a cross-sectional design, 50 adults with RA were recruited. The Arizona Food Frequency Questionnaire was used to measure dietary intake (four weeks) and diet quality scores were calculated with the Healthy Eating Index – 2015. Perceived stress was measured with the Perceived Stress Scale. Disease activity was measured with the Health Assessment Questionnaire-Disability Index and Pain Scale, erythrocyte sedimentation rate (ESR), high-sensitivity C-reactive protein, and Disease Activity Score Including 28 Joints-ESR. Results: Diet quality (56; SD ± 12) in participants was lower than the national mean (59). Age ( p = 0.015) and gender ( p = 0.003) were associated with higher diet quality. The belief that diet affects RA disease activity was reported by 44% of the participants, and these participants were significantly more likely to report dietary changes ( p < 0.0001). Higher educational level (at least some college) was associated with this belief ( B = −1.535, p = 0.023). Participants with lower diet quality also had significantly higher pain ( B = −0.396, p = 0.022) and ESR scores ( p = 0.019). Women were more likely to have higher HAQ-DI scores ( B = 0.570, p = 0.001). Perceived stress was significantly associated with HAQ-DI and pain scores ( B = 0.445, p = 0.001 and B = 0.289, p = 0.042, respectively). Medical cannabis was reportedly used by 8% of participants. Conclusion: In RA patients, lower diet quality may be associated with more pain and inflammation, and perceived stress may be associated with higher disability and disease activity.

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Influence of disease activity on functional capacity in patients with rheumatoid arthritis

Cited by 6 publications

References 11 publications

Diet quality of individuals with rheumatoid arthritis using the Healthy Eating Index (HEI)-2010

Diet quality of individuals with rheumatoid arthritis using the Healthy Eating Index (HEI)-2010

Trends in Prevalence of Functional Disability in Rheumatoid Arthritis Compared With the General Population

Diet quality and disease activity in rheumatoid arthritis

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