Influence of dietary arginine concentration on lymphoid organ growth in chickens

Kwak, Ho Young; Austic, R. E.; Dietert, R. R.

doi:10.1093/ps/78.11.1536

Cited by 91 publications

(75 citation statements)

References 29 publications

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“…However, both the relative weight of the lymphoid organs and the concentration of IgG in RO-DSW group were numerically higher than the values in the control birds. This result is similar to Kwak et al (1999) who reported that either enhanced or depressed immune responses are depended on the nutrients level, more specifically the level of specific minerals that are also required for optimal development of immune organs. The development of the thymus and bursa of Fabricius as the part of lymphoid tissue has been described (Payne, 1971;Rose, 1979).…”

Section: The Relative Weight Of the Lymphoid Organs And Serum Immunogsupporting

confidence: 90%

Effects of Drinking Reverse-osmosis Treated Deep Sea Water on Growth Performance and Immune Response in Broiler Chickens

Keohavong¹,

Lee²,

Lee³

et al. 2010

Journal of Animal Science and Technology

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This study was executed to investigate the effects of drinking deep sea water treated by reverse osmosis process (RO-DSW) on growth performance, nutrient utilizability, relative weight of lymphoid organs and the concentration of serum immunoglobulin G (IgG) in broiler chickens. A total of 200 one day old broiler chickens (Ross 308) were equally and randomly distributed into 10 ground floor pens (20 chicks per pen, 5 pens per treatment) bedded with rice-husks. The broilers were offered either fresh tap water (Control) or RO-DSW for 28 days (from d 6 to d 33) as the drinking water. The same basal phase 1 diet for first 2 weeks and phase 2 diet for last 2 weeks were offered ad libitum to the birds. The RO-DSW was prepared by diluting 1:20 ratio with deionized water before offering to chickens. The diet for control birds was supplemented with 0.21 % of food-grade salt to satisfy salt need of the birds. Broiler feeding study resulted that there were no differences in amount of water consumption, mortality and FCR between RO-DSW and control chickens. However, feed intake and body weight gain were increased (p<0.05) by RO-DSW drinking. There was no (p>0.05) difference in nutrients utilizability between RO-DSW and fresh water drinking. There were no (p>0.05) differences in the immune response between the control and treatment group. The serum IgG levels were 3.01 vs 2.87 mg/ml and the relative weights of spleen, thymus and bursa of Fabricius were 0.23, 0.18 and 0.20 vs. 0.20, 0.17 and 0.14 for RO-DSW vs. control birds, respectively. The immune responses were tended to be improved by RO-DSW drinking. This study showed an improvement in weight gain and feed intake that could be induced by RO-DSW drinking, although it is difficult to explain the reasons of the improvement at this moment. This study implied that RO-DSW could be successfully used as drinking water to broiler chickens.

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Section: The Relative Weight Of the Lymphoid Organs And Serum Immunogsupporting

confidence: 90%

Effects of Drinking Reverse-osmosis Treated Deep Sea Water on Growth Performance and Immune Response in Broiler Chickens

Keohavong¹,

Lee²,

Lee³

et al. 2010

Journal of Animal Science and Technology

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“…In the present study, head kidney and spleen weights of Jian carp increased with increasing dietary arginine concentrations, suggesting beneficial effects of arginine on head kidney and spleen growth. Similarly, arginine supplementation has improved spleen weight in chickens [49] and mice [50]. Budiño et al [51] showed that turbot (P. maxima L) with low number of erythrocytes and leukocytes may be more susceptible to diseases.…”

Section: Discussionmentioning

confidence: 99%

Effect of dietary arginine on the immune response and gene expression in head kidney and spleen following infection of Jian carp with Aeromonas hydrophila

Chen

Liu

Jiang

et al. 2015

Fish & Shellfish Immunology

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“…Previous studies in broiler chickens demonstrated the effect of adequate or higher Arg levels described in National Research Council (NRC) on growth performance and immunity (Kwak et al 1999, Corzo et al 2003, Cengiz and Kuçukersan 2010. However, to the authors; knowledge, there are no previous studies performed to investigate the effect of diet formulated with decreased and progressively increased Arg on growth performance during three time periods, as well as on NO metabolism and large intestinal motility.…”

Section: Introductionmentioning

confidence: 99%

“…Arginine is an essential dibasic amino acid for adult chickens as well as growing animals (Lee et al 2002). It has beneficial effects on immune function of poultry (Kwak et al 1999, Lee et al 2002. Arginine is also involved in wound healing (Evoy et al 1998) and improves immunity against some avian parasites (Allen and Fetterer 2000).…”

Section: Introductionmentioning

confidence: 99%

“…Arginine is also involved in wound healing (Evoy et al 1998) and improves immunity against some avian parasites (Allen and Fetterer 2000). Studies show that immunity is supported by the addition of Arg to the diet due to the enhanced release of nitric oxide (NO) from macrophages (Sung et al 1991, Webel et al 1998, the weight of lymphoid organs (Kwak et al 1999), and the ratio of heterophils/lymphocytes (Su and Austic 1998;Lee et al 2002). However, the addition of too much Arg to the diet of broiler chicks is not associated with any significant changes in the weight of lymphoid organs or plasma antibody concentrations of those vaccinated against Newcastle disease virus (ND) (Kidd et al 2001).…”

Section: Introductionmentioning

confidence: 99%

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The effect of dietary L-arginine intake on the level of antibody titer, the relative organ weight and colon motility in broilers

Bülbül¹,

Özdemir²,

Bülbül³

et al. 2014

Polish Journal of Veterinary Sciences

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This study was carried out to determine the effect of L-arginine (L-Arg) levels in diet at the starter, grower and finisher phases on immune response, organ development, nitric oxide (NO) metabolism and colon motility in broilers. A total of 500 one-day-old Ross-308 broiler chickens of mixed sex were separated into one Arg-deficient group and four experimental groups. Each group was then divided into five subgroups of 20 birds each. Arginine deficient group for all phases was fed a basal diet which contained 10% less L-Arg than optimum Arg requirement recommended by the breeder. Experimental groups were fed a basal diet supplemented with L-Arg which was progressively 10% increased in groups. Thus, the diet contained 90, 100, 110, 120 and 130% of optimum Arg requirement for each phases in groups, respectively.The highest serum infectious bursal disease antibody titer (IBD) was observed in the experimental group which was fed the diet containing 110% L-Arg at grower phase (P<0.05), whereas Newcastle disease antibody titer did not differ between groups. The relative weight of spleen increased in groups which were fed the diet containing 120 and 130% L-Arg at starter phase as compared to Arg-deficient group (P<0.05). The group which was fed the diet containing 110% L-Arg showed highest relative weight of bursa Fabricii at grower (P<0.05) and finisher (P<0.01) phases. It was observed that serum nitric oxide (NO) concentration decreased in Arg-deficient group (P<0.05). The amplitude of spontaneous colon contractility did not differ between groups at the end of all three phases. However, the frequency of spontaneous colon contractility in the Arg deficient group was higher at starter (P<0.05), grower (P<0.01) and finisher (P<0.05) phases.These results suggest that the supplementation of L-Arg at higher level than optimum Arg requirement in broiler diet has minimal effect on parameters investigated in the study. However, L-Arg-deficiency may negatively affect immune response and the motility of gastrointestinal system due to disruption of NO metabolism at three phases.

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Influence of dietary arginine concentration on lymphoid organ growth in chickens

Cited by 91 publications

References 29 publications

Effects of Drinking Reverse-osmosis Treated Deep Sea Water on Growth Performance and Immune Response in Broiler Chickens

Effects of Drinking Reverse-osmosis Treated Deep Sea Water on Growth Performance and Immune Response in Broiler Chickens

Effect of dietary arginine on the immune response and gene expression in head kidney and spleen following infection of Jian carp with Aeromonas hydrophila

The effect of dietary L-arginine intake on the level of antibody titer, the relative organ weight and colon motility in broilers

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