Influence of coffee on the excretion of noradrenaline and adrenaline in urine

Abstract

In field studies, the excretion rate of urinary catecholamines is very often used as an indicator of strain. Interfering effects which are due to caffeine, for example, can only be quantified if the influence of coffee consumption on the excretion of catecholamines is known quantitatively. This was the aim of our study with five subjects, on five consecutive working days, and with a strict standardization of nutrition. The urine samples were specified with respect to the following parameters: sampling period, volume, urine status, density, creatinine, noradrenaline, and adrenaline. Adrenaline showed a significant correlation with coffee consumption, whereas noradrenaline did not. Moreover, it could be demonstrated that relating the concentration of catecholamines to the creatinine excretion is insufficient for work physiology studies, especially if the urine sampling periods are as short as 2h.

Elevated Catecholamine Levels in Urine in Traffic Noise Exposed Subjects

“…Bablsch at at than 4 hours. This was not only because creatinine-related catecholamina measurements are not reliable it short sampling periods are considered [12], but also because occasional extremely short sleep may be associated with other physiological and emotional stressors, which raises the problem of confounding. Ultimately, the actual number of women in all statistical analyses was N = 195.…”