Influence of acid-etching after grit-blasted on osseointegration of titanium dental implants: in vitro and in vivo studies

Abstract

Rough implant surfaces have shown improved osseointegration rates. In a majority of dental implants, the microrough surfaces are obtained by grit blasting and/or acid-etching. The aim of this contribution was to evaluate the effects of acid-etching, after the grit-blasted treatment in titanium dental implants, on surface wettability, surface energy, osteoblast responses and its osseointegration behavior. Four surfaces were studied: as-machined, acid-etched, micro-rough by grit-blasting and the combination grit-blasted surface with acid-etched. The surfaces with increasing roughness show more osteoblastic adhered cells. This effect was most pronounced on samples blasted and blasted with acid-etching. The roughness obtained by grit-blasting is the main factor in comparison with the acid etching treatment in the biological response. These results were confirmed in vivo tests and histological analysis. The results demonstrated that the combination of the grit-blasted and acid-etched accelerated lightly bone regeneration at the different periods of implantation in comparison with the grit-blasted implants.

The influence of direct laser metal sintering implants on the early stages of osseointegration in diabetic mini-pigs

“…Modification of implant surfaces can improve the biological behavior around implants and can accelerate the process of osseointegration. 28 The roughness and shape of the cavities …”

Research on Improving the Manufacturing of Titanium Medical Implants, by SLM

“…Given the international medical trends, the present pieces of research contributed to the possibility of direct manufacturing of Ra roughness implants between 3-4 µm. This roughness is considered by doctors to represent the ideal surface that directly influences the mechanical fixation of the new bone tissue to the implant [11] . By reducing the roughness of the manufactured SLM pieces there will be a leading to the optimization of the post-processing methods, and the correlation of the process parameters (associated with the scanning of the outline) with the amount of the laser's adjustment beam, it reduces the dimensional deviation from ±0,1 mm to ±0,05 mm.…”

“…In vivo tests prove the fact that the treat surfaces can generate a better and faster osseointegration, in comparison with the even surfaces. From a clinical point of view, several studies have reported that on a long term the failure rate is lower in the case of the rough implants because they ensure the adhesion, the osteoblast cells proliferation and differentiation at the metal-bone interface [7,8,9,10,11] .…”

Biological characterization of implant surfaces - in vitro study

“…Tissue and cellular responses to the composition of the implant surface, specifically to the physical and chemical characteristics, have determined the clinical success of the procedures performed [2][3][4] . The osseointegration of titanium may be influenced by various mechanisms, especially the surface properties represented by the chemical characteristics such as structural composition; mechanical, such a residual stress; and, physical, such as wettability.…”