2014
DOI: 10.1186/1475-2840-13-87
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Influence of a family history of type 2 diabetes, demographic and clinical data on carotid intima-media thickness in patients with type 1 diabetes: a cross-sectional study

Abstract: BackgroundIntima-media thickness (IMT) of the common carotid artery is a surrogate end point of cardiovascular disease (CVD). Identifying the factors associated with a higher IMT may contribute to the identification of subjects with higher CVD risk. Our objective was to compare the common carotid IMT of type 1 diabetes patients to healthy control subjects. The secondary objective was to determine factors associated with a higher carotid IMT.MethodsWe conducted a cross-sectional study between March 2009 and Oct… Show more

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Cited by 17 publications
(17 citation statements)
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References 59 publications
(68 reference statements)
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“…It was recently reported in patients with DM1 of long duration there was a 0.4% increase in IMT for each year of disease duration [37], as we were also able to demonstrate. Age and diabetes duration had an additive effect on the IMT of DM1 patients.…”
Section: Discussionsupporting
confidence: 86%
“…It was recently reported in patients with DM1 of long duration there was a 0.4% increase in IMT for each year of disease duration [37], as we were also able to demonstrate. Age and diabetes duration had an additive effect on the IMT of DM1 patients.…”
Section: Discussionsupporting
confidence: 86%
“…Clinical trials have shown that diastolic blood pressure in the highest quintile, even without the added risks of high cholesterol and smoking, still contributes significantly to the risk of atherosclerosis (35,36). Our data corroborate this knowledge, as hypertension correlated positively with CIMT and carotid plaques and was more frequently diagnosed in patients with carotid obstruction.…”
Section: Discussionsupporting
confidence: 81%
“…This finding contrasts with previous studies that have demonstrated that CIMT increases with the duration of type 1 DM (19,20,36). In these studies, the duration of the disease was shorter than that in our study, which might explain our findings.…”
Section: Discussioncontrasting
confidence: 56%
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