Inflammatory pseudotumour associated with chronic persistent Eikenella corrodens infection: a case report and brief review

Sh, Lee

doi:10.1136/jcp.56.11.868

Cited by 35 publications

(27 citation statements)

References 5 publications

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“…53 E. corrodens is a normal component of the microbiota of the oral cavity 54 and the mucosal surface of the gastrointestinal and genitourinary tracts 55 ; however, its potential to act as a pathogen has been well documented. 53,[56][57][58][59][60] Given its documented history of pathogenicity, further research on the potential role of Eikenella corrodens in CRC etiology is warranted. Fusobacterium has been associated with colorectal tumors and adenomas in several recent studies.…”

Section: Discussionmentioning

confidence: 99%

Gut microbiome compositional and functional differences between tumor and non-tumor adjacent tissues from cohorts from the US and Spain

Delgado²,

et al. 2015

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Colorectal cancer (CRC) is the third most common cancer in the world and the second leading cause of cancer deaths in the US and Spain. The molecular mechanisms involved in the etiology of CRC are not yet elucidated due in part to the complexity of the human gut microbiota. In this study, we compared the microbiome composition of 90 tumor and matching adjacent tissue (adjacent) from cohorts from the US and Spain by 16S rRNA amplicon sequencing in order to determine the impact of the geographic origin on the CRC microbiome. Data showed a significantly (P < 0.05) higher Phylogenetic Diversity ( Predicted metagenome functional content from 16S rRNA surveys showed that bacterial motility proteins and proteins involved in flagellar assembly were over represented in adjacent tissues of both cohorts, while pathways involved in fatty acid biosynthesis, the MAPK signaling pathway, and bacterial toxins were over represented in tumors. Our study suggests that microbiome compositional and functional dissimilarities by geographic location should be taken in consideration when approaching CRC therapeutic options.

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Section: Discussionmentioning

confidence: 99%

Gut microbiome compositional and functional differences between tumor and non-tumor adjacent tissues from cohorts from the US and Spain

Delgado²,

et al. 2015

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“…Although this tumor is benign, its pathogenesis and behavior are not well known and the prognosis is occasionally poor. 1 We report a case of IMT originating in the left kidney in a 9-year-old girl. 5.5 cm and weighed 200 g. On cut section, there was a well-demarcated whitish fibrotic mass in the upper pole, 5.5 cm in diameter (Fig.…”

Section: Introductionmentioning

confidence: 98%

Inflammatory Myofibroblastic Tumor of the Kidney in a Child: Report of a Case

Boo

Kim

et al. 2006

Surg Today

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Inflammatory myofibroblastic tumor (IMT), also known as inflammatory pseudotumor, is an uncommon benign tumor that has been reported in various locations throughout the body, but rarely in the kidney. To our knowledge, only 22 cases of renal IMT have been described in the literature. Renal IMT in children is difficult to differentiate from a malignancy such as Wilms' tumor. We report a case of a 9-year old girl with a left renal mass mimicking malignancy on preoperative diagnostic images, which was pathologically revealed to be an IMT. We review the literature and discuss the pathophysiology and clinical features of this unusual tumor.

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“…Infective, inflammatory, reparative, and immunological processes have all been postulated. There are rare reports of its occurrence secondary to chronic infection with such fastidious organisms like Eikennella corrodens [13]. In our case, no microorganism was recovered from blood or urine cultures.…”

Section: Discussionmentioning

confidence: 88%

Lower abdominal inflammatory myofibroblastic tumor -an unusual presentation- a case report and brief literature review

et al. 2006

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A 9-year-old girl presented with lethargy, malaise & chest pain. Her blood counts confirmed hypochromic microcytic anemia. She was prescribed iron supplements. Subsequently she was admitted to our hospital with fever and increasing chest and abdominal pain. She was treated with antibiotics, and a diagnosis of "early chest infection" was made. Over the following 2 weeks she failed to improve, and her anemia worsened. She was readmitted, and found to have a mass in her lower abdomen with pressure symptoms on her bowel and bladder. A white-cell scan showed increased uptake in right lower quadrant. An ultrasound and a CT scan confirmed a mass adjacent to her bladder. Needle biopsy showed it to be an unusual localization of an inflammatory myofibroblastic tumor (IMT) of cecum. A presentation with chest pain, fever, anemia and pressure symptoms was highly unusual of a lower abdominal IMT mass. She had a successful excision of the tumor, with resolution of her symptoms.

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Inflammatory pseudotumour associated with chronic persistent Eikenella corrodens infection: a case report and brief review

Cited by 35 publications

References 5 publications

Gut microbiome compositional and functional differences between tumor and non-tumor adjacent tissues from cohorts from the US and Spain

Gut microbiome compositional and functional differences between tumor and non-tumor adjacent tissues from cohorts from the US and Spain

Inflammatory Myofibroblastic Tumor of the Kidney in a Child: Report of a Case

Lower abdominal inflammatory myofibroblastic tumor -an unusual presentation- a case report and brief literature review

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